Temozolomide - ≥98% (HPLC), high purity , DNA inhibitor, CAS No.85622-93-1, DNA inhibitor

Item Number

T127425

• Synonyms: 4-methyl-5-oxo-2,3,4,6,8-pentazabicyclo[4.3.0]nona-2,7,9-triene-9-carboxamide | CCRG 81045 | NSC 362856 | TMZ | 3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide | 8-Carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one | TZM
• Specifications & Purity: Moligand™, ≥98%(HPLC)
• Biochemical and Physiological Mechanisms: enzyme. Research has also been conducted to determine whether MGMT inhibitors such as O-6-benzylguanine might help to increase the efficacy of temozolomide. Furthermore, temozolomide has been implicated in causing arrest at the G2/M cell cycle checkpoint,
• Storage Temp: Store at 2-8°C,Argon charged
• Shipped In: Wet ice
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: DNA inhibitor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Temozolomide is a DNA damage inducer.
An apoptosis inducer which causes arrest at the G2/M cell cycle checkpoint.