Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
T463880-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $375.90 |
Synonyms | Tephrosin | 76-80-2 | hydroxydeguelin | deguelinol I | (-)-TEPHROSIN | CHEBI:9442 | 9C081V83CC | (1R,14R)-14-hydroxy-17,18-dimethoxy-7,7-dimethyl-2,8,21-trioxapentacyclo[12.8.0.03,12.04,9.015,20]docosa-3(12),4(9),5,10,15,17,19-heptaen-13-one | 3H-Bis(1)benzopyrano(3,4-b: |
---|---|
Specifications & Purity | ≥95%(LC/MS-ELSD) |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | Description Natural product derived from plant source. |
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
IUPAC Name | (1R,14R)-14-hydroxy-17,18-dimethoxy-7,7-dimethyl-2,8,21-trioxapentacyclo[12.8.0.03,12.04,9.015,20]docosa-3(12),4(9),5,10,15,17,19-heptaen-13-one |
---|---|
INCHI | InChI=1S/C23H22O7/c1-22(2)8-7-12-15(30-22)6-5-13-20(12)29-19-11-28-16-10-18(27-4)17(26-3)9-14(16)23(19,25)21(13)24/h5-10,19,25H,11H2,1-4H3/t19-,23-/m1/s1 |
InChi Key | AQBZCCQCDWNNJQ-AUSIDOKSSA-N |
Canonical SMILES | CC1(C=CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4(C3=O)O)OC)OC)C |
Isomeric SMILES | CC1(C=CC2=C(O1)C=CC3=C2O[C@@H]4COC5=CC(=C(C=C5[C@@]4(C3=O)O)OC)OC)C |
PubChem CID | 114909 |
UN Number | 3077 |
Molecular Weight | 410.42 |
Enter Lot Number to search for COA:
Flash Point(°F) | Not applicable |
---|---|
Flash Point(°C) | Not applicable |
Pictogram(s) | GHS09 |
---|---|
Signal | Warning |
Hazard Statements | H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects |
Precautionary Statements | P273:Avoid release to the environment. P501:Dispose of contents/container to ... P391:Collect spillage. |
Class | 9 |
RIDADR | UN 3077 9 / PGIII |
1. Abiy Yenesew,Solomon Derese,Jacob O Midiwo,Matthias Heydenreich,Martin G Peter. (2003-10-17) Effect of rotenoids from the seeds of Millettia dura on larvae of Aedes aegypti.. Pest management science, 59 ((10)): (1159-1161). [PMID:14561074] |
2. Shugeng Cao,Jennifer K Schilling,James S Miller,Rabodo Andriantsiferana,Vincent E Rasamison,David G I Kingston. (2004-03-27) Cytotoxic compounds from Mundulea chapelieri from the Madagascar Rainforest.. Journal of natural products, 67 ((3)): (454-456). [PMID:15043430] |
3. Abiy Yenesew,John T Kiplagat,Solomon Derese,Jacob O Midiwo,Jacques M Kabaru,Matthias Heydenreich,Martin G Peter. (2006-02-18) Two unusual rotenoid derivatives, 7a-O-methyl-12a-hydroxydeguelol and spiro-13-homo-13-oxaelliptone, from the seeds of Derris trifoliata.. Phytochemistry, 67 ((10)): (988-991). [PMID:16483619] |
4. Hisashi Matsuda,Kazutoshi Yoshida,Katsutoshi Miyagawa,Yasunobu Asao,Saya Takayama,Souichi Nakashima,Fengming Xu,Masayuki Yoshikawa. (2006-12-13) Rotenoids and flavonoids with anti-invasion of HT1080, anti-proliferation of U937, and differentiation-inducing activity in HL-60 from Erycibe expansa.. Bioorganic & medicinal chemistry, 15 ((3)): (1539-1546). [PMID:17158054] |
5. Haoyu Ye,Lijuan Chen,Yanfang Li,Aihua Peng,Afu Fu,Hang Song,Minghai Tang,Houding Luo,Youfu Luo,Yongbin Xu,Jianyou Shi,Yuquan Wei. (2007-12-18) Preparative isolation and purification of three rotenoids and one isoflavone from the seeds of Millettia pachycarpa Benth by high-speed counter-current chromatography.. Journal of chromatography. A, 1178 ((1-2)): (101-107). [PMID:18082754] |
6. José Garcia,Sofia Barluenga,Kristin Beebe,Len Neckers,Nicolas Winssinger. (2010-06-24) Concise modular asymmetric synthesis of deguelin, tephrosin and investigation into their mode of action.. Chemistry (Weinheim an der Bergstrasse, Germany), 16 ((32)): (9767-9771). [PMID:20572190] |
7. Song Gao,Ya-ming Xu,Frederick A Valeriote,A A Leslie Gunatilaka. (2011-04-02) Pierreiones A-D, solid tumor selective pyranoisoflavones and other cytotoxic constituents from Antheroporum pierrei.. Journal of natural products, 74 ((4)): (852-856). [PMID:21452840] |
8. Yunjin Choi,Jeong-Hyung Lee. (2011-11-30) The combination of tephrosin with 2-deoxy-D-glucose enhances the cytotoxicity via accelerating ATP depletion and blunting autophagy in human cancer cells.. Cancer biology & therapy, 12 ((11)): (989-996). [PMID:22123175] |
9. Lu-Rong Xu,Shan Li,Jun Wu,Si Zhang. (2007-10-09) [Rotenoids from Derris trifoliata].. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 30 ((6)): (660-662). [PMID:17918433] |
10. Tsung-Hsien Chou,Ih-Sheng Chen,Tsong-Long Hwang,Tai-Chi Wang,Tzong-Huei Lee,Lin-Yang Cheng,Ya-Chih Chang,Jui-Ying Cho,Jih-Jung Chen. (2008-09-27) Phthalides from Pittosporum illicioides var. illicioides with inhibitory activity on superoxide generation and elastase release by neutrophils.. Journal of natural products, 71 ((10)): (1692-1695). [PMID:18817445] |
11. Nguyen Tien Dat,Jeong-Hyung Lee,Kyeong Lee,Young-Soo Hong,Young Ho Kim,Jung Joon Lee. (2008-10-10) Phenolic constituents of Amorpha fruticosa that inhibit NF-kappaB activation and related gene expression.. Journal of natural products, 71 ((10)): (1696-1700). [PMID:18841906] |
12. Sujin Choi,Yunjin Choi,Nguyen Tien Dat,Cheol Hwangbo,Jung Joon Lee,Jeong-Hyung Lee. (2010-01-09) Tephrosin induces internalization and degradation of EGFR and ErbB2 in HT-29 human colon cancer cells.. Cancer letters, 293 ((1)): (23-30). [PMID:20056314] |
13. Jing Li,Xiao-Lu Wang,Yu-Chun Fang,Chang-Yun Wang. (2010-11-10) Tephrosin-induced autophagic cell death in A549 non-small cell lung cancer cells.. Journal of Asian natural products research, 12 ((11)): (992-1000). [PMID:21061222] |
14. Xueling Qu,Yunpeng Diao,Zhen Zhang,Shouyu Wang,Yujie Jia. (2013-10-23) Evaluation of anti-bacterial and wound healing activity of the fruits of Amorpha fruticosa L.. African journal of traditional, complementary, and alternative medicines : AJTCAM, 10 ((3)): (458-468). [PMID:24146475] |