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TER14687 - >95%, high purity , CAS No.16931-84-3
a compound preventing normal translocation of PKCq in T cells
Basic Description Synonyms SCHEMBL2124625 | MDMDVFGTTVMMRV-UHFFFAOYSA-N | FT-0756384 | ter14687 | NSC26626 | NSC-26626 | J-010525 | 2-((Dimethylamino)methyl)-2,3-dihydro-1H-inden-1-one hydrochloride | BDBM50497530 | 2-[(dimethylamino)methyl]-2,3-dihydroinden-1-one;hydrochloride | P Specifications & Purity ≥95% Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description TER14687 blocks the association between protein kinase Cq-V1 and p59|fyn|in a yeast reporter assay. TER14687 also prevents normal translocation of PKCq in T cells. The compound has no effect on other PKC isozymes in Jurkat or normal T cells.
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name 2-[(dimethylamino)methyl]-2,3-dihydroinden-1-one;hydrochloride INCHI InChI=1S/C12H15NO.ClH/c1-13(2)8-10-7-9-5-3-4-6-11(9)12(10)14;/h3-6,10H,7-8H2,1-2H3;1H InChi Key MDMDVFGTTVMMRV-UHFFFAOYSA-N Canonical SMILES CN(C)CC1CC2=CC=CC=C2C1=O.Cl Isomeric SMILES CN(C)CC1CC2=CC=CC=C2C1=O.Cl PubChem CID 204802 Molecular Weight 225.71
Chemical and Physical Properties Solubility Soluble in H2O Boil Point(°C) 285.9° C at 760 mmHg (Predicted)
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