Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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T129208-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $9.90 | |
T129208-250mg | 250mg | In stock | $17.90 | |
T129208-1g | 1g | In stock | $55.90 | |
T129208-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $164.90 | |
T129208-10g | 10g | In stock | $295.90 | |
T129208-25g | 25g | In stock | $665.90 | |
T129208-100g | 100g | In stock | $2,396.90 |
Synonyms | terbinafine | 91161-71-6 | Lamisil | Lamasil | (E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine | Lamisil Tablet | SF-86-327 | Lamisil AT | Terbinafina | SF 86-327 | (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine | terbinafin | Terbinaf |
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Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | Terbinafine is an allylamine antifungal agent which has fungicidal activity against a wide variety of dermatophytes, moulds and certain dimorphic fungi, and fungistatic activity against Candida albicans. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Action Type | INHIBITOR |
Mechanism of action | Squalene monooxygenase inhibitor |
Product Description | Terbinafine is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth. |
ALogP | 5.6 |
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IUPAC Name | (E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine |
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INCHI | InChI=1S/C21H25N/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19/h5-7,9-14H,16-17H2,1-4H3/b9-5+ |
InChi Key | DOMXUEMWDBAQBQ-WEVVVXLNSA-N |
Canonical SMILES | CC(C)(C)C#CC=CCN(C)CC1=CC=CC2=CC=CC=C21 |
Isomeric SMILES | CC(C)(C)C#C/C=C/CN(C)CC1=CC=CC2=CC=CC=C21 |
Alternate CAS | 91161-71-6 |
PubChem CID | 1549008 |
MeSH Entry Terms | (E)-N-(6,6-dimethyl-2-heptenynyl)-N-methyl-1-naphthalenementhamin hydrochloride;DA 5505;Lamisil;SF 86 327;SF 86-327;SF 86327;SF-86-327;SF86327;TDT 067;TDT-067;TDT067;terbinafine;terbinafine hydrochloride;Terbinafine, (Z)-;terbinafine, (Z)-isomer |
Molecular Weight | 291.43 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
G2404046 | Certificate of Analysis | Jul 16, 2024 | T129208 |
F1623055 | Certificate of Analysis | Oct 18, 2023 | T129208 |
H2131402 | Certificate of Analysis | Jun 12, 2023 | T129208 |
H2131394 | Certificate of Analysis | Jun 12, 2023 | T129208 |
H2131397 | Certificate of Analysis | Jun 12, 2023 | T129208 |
H2131398 | Certificate of Analysis | Jun 12, 2023 | T129208 |
G2105050 | Certificate of Analysis | Apr 17, 2023 | T129208 |
G2105049 | Certificate of Analysis | Apr 17, 2023 | T129208 |
K2317060 | Certificate of Analysis | Jul 23, 2022 | T129208 |
J2213890 | Certificate of Analysis | Jul 23, 2022 | T129208 |
J2213881 | Certificate of Analysis | Jul 23, 2022 | T129208 |
J2213879 | Certificate of Analysis | Jul 23, 2022 | T129208 |
J2213878 | Certificate of Analysis | Jul 23, 2022 | T129208 |
J2213877 | Certificate of Analysis | Jul 23, 2022 | T129208 |
J2213812 | Certificate of Analysis | Jul 23, 2022 | T129208 |
G2411048 | Certificate of Analysis | Jul 23, 2022 | T129208 |
C2415126 | Certificate of Analysis | Jul 23, 2022 | T129208 |
C2205116 | Certificate of Analysis | Mar 15, 2022 | T129208 |
Solubility | Soluble in DMSO (≥58 mg/mL) at 25 °C, water (<1 mg/mL) at 25 °C, and ethanol (≥58 mg/mL) at 25 °C. |
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Sensitivity | Heat sensitive |
Melt Point(°C) | 43 °C |
Pictogram(s) | GHS09 |
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Signal | Warning |
Hazard Statements | H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects |
Precautionary Statements | P273:Avoid release to the environment. P501:Dispose of contents/container to ... P391:Collect spillage. |
Merck Index | 9156 |
1. Yue Qun, Meng Jie, Qiu Yue, Yin Miaomiao, Zhang Liwen, Zhou Weiping, An Zhiqiang, Liu Zihe, Yuan Qipeng, Sun Wentao, Li Chun, Zhao Huimin, Molnár István, Xu Yuquan, Shi Shuobo. (2023) A polycistronic system for multiplexed and precalibrated expression of multigene pathways in fungi. Nature Communications, 14 (1): (1-10). [PMID:37460548] |
2. Meng Wang, Yanwen Zhou, Zhaohui Wang. (2023) Unearth the ultrapotent intrinsic fungicidal efficacy of the surface-piercing CuFeSe2-PVP nano-blade. CHEMICAL ENGINEERING JOURNAL, 464 (142603). [PMID:] |
3. Hui Lu, Wanqian Li, Malcolm Whiteway, Hongkang Wang, Shuo Zhu, Zhe Ji, Yanru Feng, Lan Yan, Ting Fang, Liping Li, Tingjunhong Ni, Xiaolong Zhang, Quanzhen Lv, Zichao Ding, Lijuan Qiu, Dazhi Zhang, Yuanying Jiang. (2022) A Small Molecule Inhibitor of Erg251 Makes Fluconazole Fungicidal by Inhibiting the Synthesis of the 14α-Methylsterols. mBio, 14 (1): [PMID:36475771] |
4. Guo Penghao, Chen Jianlong, Tan Yiwei, Xia Li, Zhang Weizheng, Li Xiaojie, Jiang Yujie, Li Ruiying, Chen Chunmei, Liao Kang, Peng Yaqin. (2022) Comparison of molecular and MALDI-TOF MS identification and antifungal susceptibility of clinical Fusarium isolates in Southern China. Frontiers in Microbiology, 13 [PMID:36386677] |
1. Yue Qun, Meng Jie, Qiu Yue, Yin Miaomiao, Zhang Liwen, Zhou Weiping, An Zhiqiang, Liu Zihe, Yuan Qipeng, Sun Wentao, Li Chun, Zhao Huimin, Molnár István, Xu Yuquan, Shi Shuobo. (2023) A polycistronic system for multiplexed and precalibrated expression of multigene pathways in fungi. Nature Communications, 14 (1): (1-10). [PMID:37460548] |
2. Meng Wang, Yanwen Zhou, Zhaohui Wang. (2023) Unearth the ultrapotent intrinsic fungicidal efficacy of the surface-piercing CuFeSe2-PVP nano-blade. CHEMICAL ENGINEERING JOURNAL, 464 (142603). [PMID:] |
3. Hui Lu, Wanqian Li, Malcolm Whiteway, Hongkang Wang, Shuo Zhu, Zhe Ji, Yanru Feng, Lan Yan, Ting Fang, Liping Li, Tingjunhong Ni, Xiaolong Zhang, Quanzhen Lv, Zichao Ding, Lijuan Qiu, Dazhi Zhang, Yuanying Jiang. (2022) A Small Molecule Inhibitor of Erg251 Makes Fluconazole Fungicidal by Inhibiting the Synthesis of the 14α-Methylsterols. mBio, 14 (1): [PMID:36475771] |
4. Guo Penghao, Chen Jianlong, Tan Yiwei, Xia Li, Zhang Weizheng, Li Xiaojie, Jiang Yujie, Li Ruiying, Chen Chunmei, Liao Kang, Peng Yaqin. (2022) Comparison of molecular and MALDI-TOF MS identification and antifungal susceptibility of clinical Fusarium isolates in Southern China. Frontiers in Microbiology, 13 [PMID:36386677] |