Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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T129278-1g | 1g | In stock | $103.90 | |
T129278-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $353.90 | |
T129278-25g | 25g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,590.90 | |
T129278-100g | 100g | In stock | $5,725.90 | |
T129278-500g | 500g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $25,762.90 |
Antifungal and antimycotic
Synonyms | SMR000469152 | TERBINAFINE HYDROCHLORIDE [JAN] | TERBINAFINE HYDROCHLORIDE [MART.] | C21H26ClN | Terbinafine hydrochloride (JP17/USP) | Terbinafinum (Latin) | Terbisil | trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthylmethylamine Hydrochloride | |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Terbinafine hydrochloride is a synthetic allylamine antifungal, which is highly active against dermatophytes, mold, other basic fungi, and some strains of yeast. Terbinafine hydrochloride is used to treat dermatophyte infections of the toenail/fingernail |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Terbinafine HCl inhibits ergosterol synthesis by inhibiting squalene epoxidase, used as an antifungal drug. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine;hydrochloride |
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INCHI | InChI=1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+; |
InChi Key | BWMISRWJRUSYEX-SZKNIZGXSA-N |
Canonical SMILES | CC(C)(C)C#CC=CCN(C)CC1=CC=CC2=CC=CC=C21.Cl |
Isomeric SMILES | CC(C)(C)C#C/C=C/CN(C)CC1=CC=CC2=CC=CC=C21.Cl |
WGK Germany | 3 |
RTECS | QJ8600100 |
Alternate CAS | 91161-71-6 |
NSC Number | 759113 |
MeSH Entry Terms | (E)-N-(6,6-dimethyl-2-heptenynyl)-N-methyl-1-naphthalenementhamin hydrochloride;DA 5505;Lamisil;SF 86 327;SF 86-327;SF 86327;SF-86-327;SF86327;TDT 067;TDT-067;TDT067;terbinafine;terbinafine hydrochloride;Terbinafine, (Z)-;terbinafine, (Z)-isomer |
Molecular Weight | 327.89 |
Reaxy-Rn | 5660449 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
L2402040 | Certificate of Analysis | Nov 29, 2024 | T129278 |
L2409649 | Certificate of Analysis | Nov 29, 2024 | T129278 |
L2409650 | Certificate of Analysis | Nov 29, 2024 | T129278 |
L2412042 | Certificate of Analysis | Nov 29, 2024 | T129278 |
L2412043 | Certificate of Analysis | Nov 29, 2024 | T129278 |
L2412044 | Certificate of Analysis | Nov 29, 2024 | T129278 |
L2412045 | Certificate of Analysis | Nov 29, 2024 | T129278 |
C2422067 | Certificate of Analysis | Apr 01, 2024 | T129278 |
E1705065 | Certificate of Analysis | Jan 12, 2023 | T129278 |
F2406070 | Certificate of Analysis | Dec 24, 2022 | T129278 |
L2212296 | Certificate of Analysis | Dec 24, 2022 | T129278 |
D1904107 | Certificate of Analysis | Dec 08, 2022 | T129278 |
H2310086 | Certificate of Analysis | Dec 08, 2022 | T129278 |
Solubility | DMSO 66 mg/mL Water <1 mg/mL Ethanol 66 mg/mL |
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Boil Point(°C) | 417.9° C at 760 mmHg |
Melt Point(°C) | 214℃ |
Pictogram(s) | GHS09, GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | QJ8600100 |
Reaxy-Rn | 5660449 |
Merck Index | 9156 |
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