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Tetrabutylammonium fluoride solution - 1.0 M in THF, high purity , CAS No.429-41-4(THF)

1.0 M in THF

CAS#: 429-41-4(THF)
MDL number: MFCD00011747
PubChem CID: 2724141

Item Number

T106821

Grouped product items
SKU	Size	Availability	Price
T106821-25ml	25ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$24.90
T106821-100ml	100ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$57.90
T106821-500ml	500ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$164.90

View related series

Ammonium salt Deprotection Derivatization Nucleophilic fluorinating agent Protection

Basic Description

Synonyms	Tetrabutylammonium fluoride\|429-41-4\|tetrabutylazanium fluoride\|TBAF\|Tetrabutyl ammonium fluoride\|TETRA-N-BUTYLAMMONIUM FLUORIDE\|tetrabutylammoniumfluoride\|tetrabutylazanium;fluoride\|UNII-2618F0C37I\|1-Butanaminium, N,N,N-tributyl-, fluoride\|EINECS 207-057
Specifications & Purity	1.0 M in THF
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice
Product Description	Reactant for preparation of: • Triple monoamine reuptake inhibitors as a new generation of antidepressants • Alcohols via hydrolysis of alkyl silyl ethers neutral pH in mixed organic-aqueous buffered solutions • Oligoribonucleotides with phosphonate-modified linkages • Aryl alkyl alcohols via Nozaki-Hiyama allylation catalyzed by chiral bipyridyldiol ligands and chromium trichloride • Conjugated dienoic acid esters using Suzuki coupling reactions • Macrocyclic o-aminobenzamide Hsp90 inhibitorwith antitumor activity • Phospshoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors • Anti-diabetic polyacetylenic glucosides Tetrabutylammonium fluoride (TBAF) can be used as a reagent: • For the deprotection of silyl and N-sulfonyl groups. • In the fluorination reactions. • To synthesize 2-substituted indoles by cyclization reaction of various 2-ethynylanilines with terminal alkynes using Pd catalyst. It can also be used as an activator in the synthesis of arylated or alkenylated alkynes by the coupling reaction of aryl and alkenyl halides with terminal alkynes in the presence of Pd catalyst.

Names and Identifiers

INCHI	1S/C16H36N.FH/c1-5-9-13-17(14-10-6-2,15-11-7-3)16-12-8-4;/h5-16H2,1-4H3;1H/q+1;/p-1
InChi Key	FPGGTKZVZWFYPV-UHFFFAOYSA-M
Canonical SMILES	[F-].CCCC[N+](CCCC)(CCCC)CCCC
Isomeric SMILES	CCCC[N+](CCCC)(CCCC)CCCC.[F-]
PubChem CID	2724141
UN Number	2056
Packing Group	II

Certificates

Certificate of Analysis(COA)

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23 results found

Lot Number	Certificate Type	Date	Item
H2406656	Certificate of Analysis	Jul 19, 2024	T106821
H2406655	Certificate of Analysis	Jul 19, 2024	T106821
G2213546	Certificate of Analysis	Apr 07, 2024	T106821
G2213544	Certificate of Analysis	Apr 07, 2024	T106821
F2312781	Certificate of Analysis	May 30, 2023	T106821
L2327012	Certificate of Analysis	May 30, 2023	T106821
F2312780	Certificate of Analysis	May 30, 2023	T106821
F2312779	Certificate of Analysis	May 30, 2023	T106821
F2312778	Certificate of Analysis	May 30, 2023	T106821
C2330831	Certificate of Analysis	Mar 16, 2023	T106821
C2407299	Certificate of Analysis	Mar 16, 2023	T106821
C2330892	Certificate of Analysis	Mar 16, 2023	T106821
C2330836	Certificate of Analysis	Mar 16, 2023	T106821
C2330834	Certificate of Analysis	Mar 16, 2023	T106821
K2228760	Certificate of Analysis	Sep 07, 2022	T106821
K2228761	Certificate of Analysis	Sep 07, 2022	T106821
K2228762	Certificate of Analysis	Sep 07, 2022	T106821
K2228772	Certificate of Analysis	Sep 07, 2022	T106821
G2213194	Certificate of Analysis	Jun 13, 2022	T106821
G2213195	Certificate of Analysis	Jun 13, 2022	T106821
E2223221	Certificate of Analysis	Mar 11, 2022	T106821
E2223215	Certificate of Analysis	Mar 11, 2022	T106821
E2223211	Certificate of Analysis	Mar 11, 2022	T106821

Chemical and Physical Properties

Solubility	Miscible with terahydrofuran, acetonitrile, dimethyl sulfoxide and organic solvents.
Sensitivity	Air and moisture sensitive
Flash Point(°F)	1.4 °F
Flash Point(°C)	-17 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07, GHS02
Signal	Danger
Hazard Statements	H319:Causes serious eye irritation H335:May cause respiratory irritation H351:Suspected of causing cancer H302:Harmful if swallowed H225:Highly Flammable liquid and vapor H336:May cause drowsiness or dizziness
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use ... to extinguish. P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking. P405:Store locked up. P501:Dispose of contents/container to ... P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P264:Wash hands [and …] thoroughly after handling. P403+P235:Store in a well-ventilated place. Keep cool. P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower]. P201:Obtain special instructions before use. P308+P313:IF exposed or concerned: Get medical advice/attention. P271:Use only outdoors or in a well-ventilated area. P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P337+P313:IF eye irritation persists: Get medical advice/attention. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P202:Do not handle until all safety precautions have been read and understood. P330:Rinse mouth. P301+P312:IF SWALLOWED: call a POISON CENTER/doctor/... IF you feel unwell. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge.
Class	3

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