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Tetracycline hydrochloride - analytical standard, high purity , Bacterial 70S ribosome inhibitor, CAS No.64-75-5, Bacterial 70S ribosome inhibitor

analytical standard

CAS#: 64-75-5
Formula: C₂₂H₂₄N₂O₈·HCl
Molecular Weight: 480.9
Beilstein Registry Number: 3844873
EC Number: 200-593-8
MDL number: MFCD00078142
PubChem CID: 54704426

Item Number

T105494

Grouped product items
SKU	Size	Availability	Price	Qty
T105494-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$409.90

Broad spectrum antibiotic

Basic Description

Synonyms	TETRACYCLINE HYDROCHLORIDE\|64-75-5\|Tetracycline HCl\|Achromycin hydrochloride\|Bristacycline\|Sustamycin\|Tetracycline.HCl\|Cyclopar\|Sumycin\|Tetracycline (hydrochloride)\|Achromycin V\|Neocycline b\|Vetquamycin 324\|Achromycin\|Supramycin\|Telotrex\|NCI-C55561\|NSC-75
Specifications & Purity	analytical standard
Storage Temp	Store at -20°C
Shipped In	Dry ice
Grade	analytical standard
Action Type	INHIBITOR
Mechanism of action	Bacterial 70S ribosome inhibitor
Product Description	Tetracycline is a broad spectrum polyketide antibiotic with clinical uses in treating bacterial infections such as Rocky Mountain spotted fever, typush fever, tick fevers, Q fever, and Brill-Zinsser disease and to treat upper respiratory infections and acne. It has been used in studies of multidrug resistance and potential side effects including acute pancreatitis. It is recommended for use in cell culture applications at 10 mg/L.

Names and Identifiers

IUPAC Name	(4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride
INCHI	InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
InChi Key	YCIHPQHVWDULOY-FMZCEJRJSA-N
Canonical SMILES	CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl
Isomeric SMILES	C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl
PubChem CID	54704426
Molecular Weight	480.9
Beilstein	3844873

Certificates

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Lot Number	Certificate Type	Date	Item
C2205356	Certificate of Analysis	Dec 21, 2023	T105494

Specific Rotation[α]

-253° (C=0.5,0.1mol/L HCl)

Melt Point(°C)

223°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS09, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H373:Causes damage to organs through prolonged or repeated exposure H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects H360:May damage fertility or the unborn child H361:Suspected of damaging fertility or the unborn child H362:May cause harm to breast-fed children
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P263:Avoid contact during pregnancy/while nursing. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
Merck Index	9196

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