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Tetrahydrouridine - 95%, high purity , CAS No.18771-50-1
Competitive cytidine deaminase inhibitor
Basic Description Synonyms TETRAHYDROURIDINE | 18771-50-1 | 3,4,5,6-Tetrahydrouridine | NSC-112907 | NSC 112907 | NSC112907 | 0NIZ8H6OL8 | CHEMBL2311128 | 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one | U 23284 | 2(1H)-Pyrimidinone, tetrah Specifications & Purity ≥95% Biochemical and Physiological Mechanisms Competitive cytidine deaminase inhibitor (IC 50 = 152 μM). Modulates antiproliferative effects. Orally active. Storage Temp Store at -20°C,Desiccated Shipped In Ice chest + Ice pads Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers Pubchem Sid 488183096 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488183096 IUPAC Name 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one INCHI InChI=1S/C9H16N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4-8,12-15H,1-3H2,(H,10,16)/t4-,5?,6-,7-,8-/m1/s1 InChi Key UCKYOOZPSJFJIZ-XVKVHKPRSA-N Canonical SMILES C1CN(C(=O)NC1O)C2C(C(C(O2)CO)O)O Isomeric SMILES C1CN(C(=O)NC1O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O PubChem CID 29243 Molecular Weight 248.23
Chemical and Physical Properties Solubility DMF: 16 mg/mL;DMSO: 10 mg/ml;PBS (pH 7.2): 5 mg/mL
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