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Tezampanel , CAS No.154652-83-2, Antagonist of GluA1;Antagonist of GluA2;Antagonist of GluA3;Antagonist of GluA4
Basic Description Synonyms Tezampanel | Tezampanel (anhydrous) | LY-293558 | 154652-83-2 | 150131-78-5 | Tezampanel [INN] | Tezampanel, anhydrous | LY293558 | LY 293558 | NGX-424 | LY-293,558 | 6-(2-(1H-Tetrazol-5-yl)ethyl)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid | CHEMBL14935 | GA36S2 Specifications & Purity Moligand™ Biochemical and Physiological Mechanisms Tezampanel (LY293558) is a drug which acts as an antagonist at the AMPA and kainate families of ionotropic glutamate receptors, with selectivity for the GluR5 subtype of the kainate receptor. It has neuroprotective and anticonvulsant effe
Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type ANTAGONIST Mechanism of action Antagonist of GluA1;Antagonist of GluA2;Antagonist of GluA3;Antagonist of GluA4
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name (3S,4aR,6R,8aR)-6-[2-(2H-tetrazol-5-yl)ethyl]-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid INCHI InChI=1S/C13H21N5O2/c19-13(20)11-6-10-5-8(1-3-9(10)7-14-11)2-4-12-15-17-18-16-12/h8-11,14H,1-7H2,(H,19,20)(H,15,16,17,18)/t8-,9+,10-,11+/m1/s1 InChi Key ZXFRFPSZAKNPQQ-YTWAJWBKSA-N Canonical SMILES C1CC2CNC(CC2CC1CCC3=NNN=N3)C(=O)O Isomeric SMILES C1C[C@H]2CN[C@@H](C[C@H]2C[C@H]1CCC3=NNN=N3)C(=O)O PubChem CID 127894 Molecular Weight 279.34
Chemical and Physical Properties
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