TH 1020 - ≥98%(HPLC), high purity , CAS No.1841460-82-9

Item Number

T287818

Grouped product items
SKU	Size	Availability	Price
T287818-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$117.90
T287818-50mg	50mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$444.90
T287818-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$2,002.90

Toll-like receptor (TLR) 5/Flagellin complex antagonist

Basic Description

Synonyms	4-((4-Benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)pyrido3′,2′,4,5-thieno3,2-dpyrimidine;4-4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-ylthio-pyrido3′,2′:4,5thieno3,2-dpyrimidine;4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thi
Specifications & Purity	≥98%(HPLC)
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	TH1020 has been used to inhibit toll-like receptor 5 (TLR5) in porcine intestinal epithelial monolayer cells and mice.

Associated Targets(Human)

TLR5 Tchem Toll-like receptor 5 (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TLR5 Tchem Toll-like receptor 5 (190 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	6-[(4-benzyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene
INCHI	InChI=1S/C23H15N7S2/c1-2-5-15(6-3-1)13-30-20(16-8-11-24-12-9-16)28-29-23(30)32-22-19-18(26-14-27-22)17-7-4-10-25-21(17)31-19/h1-12,14H,13H2
InChi Key	CBBXTGWSGPEJEE-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C(C=C1)CN2C(=NN=C2SC3=NC=NC4=C3SC5=C4C=CC=N5)C6=CC=NC=C6
Isomeric SMILES	C1=CC=C(C=C1)CN2C(=NN=C2SC3=NC=NC4=C3SC5=C4C=CC=N5)C6=CC=NC=C6
PubChem CID	124203921
Molecular Weight	453.54

Certificates

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot Number	Certificate Type	Date	Item
J2116096	Certificate of Analysis	Jul 08, 2024	T287818
J2116101	Certificate of Analysis	Jul 08, 2024	T287818
J2116102	Certificate of Analysis	Jul 08, 2024	T287818

Solution Calculators

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.

Basic Description