Thiamine pyrophosphate - 10mM in Water, high purity , CAS No.154-87-0

  • 10mM in Water
Item Number
T421841
Grouped product items
SKUSizeAvailabilityPrice Qty
T421841-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$69.90

Basic Description

Synonymscocarboxylase | Thiamine pyrophosphate | 154-87-0 | Thiamine pyrophosphate chloride | thiamine diphosphate | Cocarboxilasa | Cocarboxylasum | Co-carboxylase | Aneurinepyrophosphoric acid | Cocarboxylase chloride | Coenzymate | XMK8K8EVIU | MFCD00038740 | Pyrophosphoric ester of th
Specifications & Purity10mM in Water
Biochemical and Physiological MechanismsThiamine pyrophosphate is a coenzyme of transketolase that catalyzes the cleavage of ribulose-5-phosphate; thereby forming D-glyceraldehyde-3-phosph?ate. This reaction requires the addition of an acceptor aldehyde such as ribose-5-phosphate, glyceraldehye
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

decarboxylation mechanisms in biological systems,and to investigate radical reactions of thiamin pyrophosphate in 2-oxoacid oxidoreductases.

Associated Targets(Human)

ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

dxs 1-deoxy-D-xylulose-5-phosphate synthase (31 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethyl phosphono hydrogen phosphate;chloride
INCHI InChI=1S/C12H18N4O7P2S.ClH/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H4-,13,14,15,17,18,19,20,21);1H
InChi Key YXVCLPJQTZXJLH-UHFFFAOYSA-N
Canonical SMILES CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCOP(=O)(O)OP(=O)(O)O.[Cl-]
Isomeric SMILES CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCOP(=O)(O)OP(=O)(O)O.[Cl-]
WGK Germany 3
RTECS XI7552000
PubChem CID 9068
Molecular Weight 460.77
Beilstein 3875902
Reaxy-Rn 3875902

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Sensitivitylight and heat sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H317:May cause an allergic skin reaction

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P501:Dispose of contents/container to ...

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

WGK Germany 3
RTECS XI7552000
Reaxy-Rn 3875902

Related Documents

Citations of This Product

1. Su Xiaowei, Tan Wei, Liu Xiaohui, Ren Yuanlin, Sun Ying.  (2023)  Fabricating of flame retardant and antibacterial lyocell fabric based on thiamine pyrophosphate modification.  CELLULOSE,  30  (7): (4437-4454).  [PMID:] [10.1007/s10570-023-05148-1]
2. Hongyan Zhang, Ji Li, Rong Yuan, Yufen Li, Yue Zhang, Xiaoyun Hu, Jiqiang Qu, Yu Chen, Zheran Wang, Mingyu Xia, Dongkai Wang.  (2021)  Augment the efficacy of eradicating metastatic lesions and tumor proliferation in breast cancer by honokiol-loaded pH-sensitive targeted lipid nanoparticles.  COLLOIDS AND SURFACES B-BIOINTERFACES,  207  (112008).  [PMID:34333303] [10.1016/j.colsurfb.2021.112008]
3. Yan Zhang, Peiyuan Yao, Yunfeng Cui, Qiaqing Wu, Dunming Zhu.  (2018)  One-Pot Enzymatic Synthesis of Cyclic Vicinal Diols from Aliphatic Dialdehydes via Intramolecular C−C Bond Formation and Carbonyl Reduction Using Pyruvate Decarboxylases and Alcohol Dehydrogenases.  ADVANCED SYNTHESIS & CATALYSIS,  360  (21): (4191-4196).  [PMID:] [10.1002/adsc.201800455]
4. Jinbin Liu, Jing Jiang, Yajun Bai, Tai-ping Fan, Ye Zhao, Xiaohui Zheng, Yujie Cai.  (2018)  Mimicking a New 2-Phenylethanol Production Pathway from Proteus mirabilis JN458 in Escherichia coli.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  66  (13): (3498–3504).  [PMID:29560727] [10.1021/acs.jafc.8b00627]
5. Jia Xiaojing, Liu Ying, Han Yejun.  (2017)  A thermophilic cell-free cascade enzymatic reaction for acetoin synthesis from pyruvate.  Scientific Reports,  (1): (1-10).  [PMID:28659601] [10.1038/s41598-017-04684-8]
6. Zhenzhen Zhang, Jing Zhang, Yang Wang, Yao Tong, Lei Zhang.  (2017)  Controlled synthesis of hollow porous carbon spheres for enrichment and simultaneous determination of nine bisphenols from real samples.  TALANTA,  167  (428).  [PMID:28340741] [10.1016/j.talanta.2017.02.037]
7. Lingling Wang, Zhenzhen Zhang, Jing Zhang, Lei Zhang.  (2016)  Magnetic solid-phase extraction using nanoporous three dimensional graphene hybrid materials for high-capacity enrichment and simultaneous detection of nine bisphenol analogs from water sample.  JOURNAL OF CHROMATOGRAPHY A,  1463  (1).  [PMID:27507729] [10.1016/j.chroma.2016.08.003]

References

1. Su Xiaowei, Tan Wei, Liu Xiaohui, Ren Yuanlin, Sun Ying.  (2023)  Fabricating of flame retardant and antibacterial lyocell fabric based on thiamine pyrophosphate modification.  CELLULOSE,  30  (7): (4437-4454).  [PMID:] [10.1007/s10570-023-05148-1]
2. Hongyan Zhang, Ji Li, Rong Yuan, Yufen Li, Yue Zhang, Xiaoyun Hu, Jiqiang Qu, Yu Chen, Zheran Wang, Mingyu Xia, Dongkai Wang.  (2021)  Augment the efficacy of eradicating metastatic lesions and tumor proliferation in breast cancer by honokiol-loaded pH-sensitive targeted lipid nanoparticles.  COLLOIDS AND SURFACES B-BIOINTERFACES,  207  (112008).  [PMID:34333303] [10.1016/j.colsurfb.2021.112008]
3. Yan Zhang, Peiyuan Yao, Yunfeng Cui, Qiaqing Wu, Dunming Zhu.  (2018)  One-Pot Enzymatic Synthesis of Cyclic Vicinal Diols from Aliphatic Dialdehydes via Intramolecular C−C Bond Formation and Carbonyl Reduction Using Pyruvate Decarboxylases and Alcohol Dehydrogenases.  ADVANCED SYNTHESIS & CATALYSIS,  360  (21): (4191-4196).  [PMID:] [10.1002/adsc.201800455]
4. Jinbin Liu, Jing Jiang, Yajun Bai, Tai-ping Fan, Ye Zhao, Xiaohui Zheng, Yujie Cai.  (2018)  Mimicking a New 2-Phenylethanol Production Pathway from Proteus mirabilis JN458 in Escherichia coli.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  66  (13): (3498–3504).  [PMID:29560727] [10.1021/acs.jafc.8b00627]
5. Jia Xiaojing, Liu Ying, Han Yejun.  (2017)  A thermophilic cell-free cascade enzymatic reaction for acetoin synthesis from pyruvate.  Scientific Reports,  (1): (1-10).  [PMID:28659601] [10.1038/s41598-017-04684-8]
6. Zhenzhen Zhang, Jing Zhang, Yang Wang, Yao Tong, Lei Zhang.  (2017)  Controlled synthesis of hollow porous carbon spheres for enrichment and simultaneous determination of nine bisphenols from real samples.  TALANTA,  167  (428).  [PMID:28340741] [10.1016/j.talanta.2017.02.037]
7. Lingling Wang, Zhenzhen Zhang, Jing Zhang, Lei Zhang.  (2016)  Magnetic solid-phase extraction using nanoporous three dimensional graphene hybrid materials for high-capacity enrichment and simultaneous detection of nine bisphenol analogs from water sample.  JOURNAL OF CHROMATOGRAPHY A,  1463  (1).  [PMID:27507729] [10.1016/j.chroma.2016.08.003]

Solution Calculators