Basic Description

Synonyms	cocarboxylase \| Thiamine pyrophosphate \| 154-87-0 \| Thiamine pyrophosphate chloride \| thiamine diphosphate \| Cocarboxilasa \| Cocarboxylasum \| Co-carboxylase \| Aneurinepyrophosphoric acid \| Cocarboxylase chloride \| Coenzymate \| XMK8K8EVIU \| MFCD00038740 \| Pyrophosphoric ester of th
Specifications & Purity	10mM in Water
Biochemical and Physiological Mechanisms	Thiamine pyrophosphate is a coenzyme of transketolase that catalyzes the cleavage of ribulose-5-phosphate; thereby forming D-glyceraldehyde-3-phosph?ate. This reaction requires the addition of an acceptor aldehyde such as ribose-5-phosphate, glyceraldehye
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	decarboxylation mechanisms in biological systems,and to investigate radical reactions of thiamin pyrophosphate in 2-oxoacid oxidoreductases.

Associated Targets(Human)

ACHE Tclin Acetylcholinesterase (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ACHE Tclin Acetylcholinesterase (18204 Activities)

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Associated Targets(non-human)

dxs 1-deoxy-D-xylulose-5-phosphate synthase (31 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

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SARS-CoV-2 (38078 Activities)

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Names and Identifiers

IUPAC Name	2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethyl phosphono hydrogen phosphate;chloride
INCHI	InChI=1S/C12H18N4O7P2S.ClH/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H4-,13,14,15,17,18,19,20,21);1H
InChi Key	YXVCLPJQTZXJLH-UHFFFAOYSA-N
Canonical SMILES	CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCOP(=O)(O)OP(=O)(O)O.[Cl-]
Isomeric SMILES	CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCOP(=O)(O)OP(=O)(O)O.[Cl-]
WGK Germany	3
RTECS	XI7552000
PubChem CID	9068
Molecular Weight	460.77
Beilstein	3875902
Reaxy-Rn	3875902

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Sensitivity	light and heat sensitive

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H317:May cause an allergic skin reaction
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse.
WGK Germany	3
RTECS	XI7552000
Reaxy-Rn	3875902

Citations of This Product

1. Su Xiaowei, Tan Wei, Liu Xiaohui, Ren Yuanlin, Sun Ying. (2023) Fabricating of flame retardant and antibacterial lyocell fabric based on thiamine pyrophosphate modification. CELLULOSE, 30 (7): (4437-4454). [PMID:]

References

1. Su Xiaowei, Tan Wei, Liu Xiaohui, Ren Yuanlin, Sun Ying. (2023) Fabricating of flame retardant and antibacterial lyocell fabric based on thiamine pyrophosphate modification. CELLULOSE, 30 (7): (4437-4454). [PMID:]

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Thiamine pyrophosphate - 10mM in Water, high purity , CAS No.154-87-0