Thiophanate-methyl - analytical standard, high purity , CAS No.23564-05-8

Item Number
T109974
Grouped product items
SKUSizeAvailabilityPrice Qty
T109974-250mg
250mg
In stock
$102.90

Basic Description

Synonymsdimethyl [1,2-phenylenebis(iminocarbonothioyl)]biscarbamate | KBioSS_002242 | NF-44 | NSC 170811 | Spectrum_001761 | CHEBI:35014 | Frumidor | Sigma | Topsin NF-44 | methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate | Trevin |
Specifications & Purityanalytical standard
Shipped InNormal
Gradeanalytical standard

Associated Targets(Human)

PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CXCL8 Tchem Interleukin-8 (642 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lymphoblastoid cell (5959 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Faah Anandamide amidohydrolase (3907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Oculimacula yallundae (312 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Thanatephorus cucumeris (609 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cercospora beticola (433 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Fusarium oxysporum (3998 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Botrytis cinerea (4183 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Colletotrichum fragariae (147 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rhizoctonia solani (2251 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sclerotinia sclerotiorum (877 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Corynespora cassiicola (104 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Neofusicoccum australe (78 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Podosphaera fusca (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pestalotiopsis microspora (57 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Fusarium graminearum (1554 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Curvularia pallescens (106 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Diplodia mutila (102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Neofusicoccum luteum (172 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas amygdali pv. lachrymans (49 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cucurbita maxima x Cucurbita moschata (14 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Monilinia laxa (436 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Podosphaera xanthii (125 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudoperonospora cubensis (1623 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lagenaria siceraria (14 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Podosphaera fuliginea (1057 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudopestalotiopsis theae (13 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mycogone perniciosa (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Diaporthe ampelina (88 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ascochyta (23 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Clonostachys rosea (54 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plurivorosphaerella nawae (18 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Colletotrichum falcatum (178 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate
INCHI InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22)
InChi Key QGHREAKMXXNCOA-UHFFFAOYSA-N
Canonical SMILES COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC
Isomeric SMILES COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC
WGK Germany 3
RTECS BA3675000
PubChem CID 3032791
Molecular Weight 342.39
Beilstein 937942

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
L2308515Certificate of AnalysisNov 29, 2023 T109974
L2308524Certificate of AnalysisNov 29, 2023 T109974
J1916039Certificate of AnalysisMay 08, 2023 T109974

Chemical and Physical Properties

SolubilityInsoluble in water, soluble in methanol, ethanol, acetone, chloroform, etc.
Melt Point(°C)181.5-182.5°C

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS09,   GHS07
Signal Warning
Hazard Statements

H341:Suspected of causing genetic defects

H317:May cause an allergic skin reaction

H400:Very toxic to aquatic life

H332:Harmful if inhaled

H410:Very toxic to aquatic life with long lasting effects

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P281:Use personal protective equipment as required.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P203:Obtain, read and follow all safety instructions before use.

P318:if exposed or concerned, get medical advice.

P317:Get emergency medical help.

WGK Germany 3
RTECS BA3675000

Related Documents

Citations of This Product

1. Jie Zhao, Zi-Yu Li, Ting Cheng, Yan-Xin Chen, Cong Dai, Jia-Hui Zhu, Yu-Shen Liu, Lu-Liang Wang.  (2023)  Synthesis of magnetic covalent organic framework composites for effective extraction of benzimidazole fungicides from food samples.  MICROCHEMICAL JOURNAL,  195  (6): (109419).  [PMID:16491121]
2. Yu Ying, Huang Gengli, Luo Xueli, Lin Wanmei, Han Yong, Huang Jihong, Li Zhonghong.  (2022)  Carbon dots@Cu metal–organic frameworks hybrids for ratiometric fluorescent determination of pesticide thiophanate-methyl.  MICROCHIMICA ACTA,  189  (9): (1-9).  [PMID:35947204]
3. Xueli Luo, Gengli Huang, Yuchen Li, Jie Guo, Xiaokai Chen, Youwen Tan, Wenzhi Tang, Zhonghong Li.  (2022)  Dual-modes of ratiometric fluorescent and smartphone-integrated colorimetric detection of glyphosate by carbon dots encapsulated porphyrin metal–organic frameworks.  APPLIED SURFACE SCIENCE,  602  (154368).  [PMID:]
4. Gui-Yang Zhu, Ying Chen, Su-Yan Wang, Xin-Chi Shi, Daniela D. Herrera-Balandrano, Victor Polo, Pedro Laborda.  (2022)  Peel Diffusion and Antifungal Efficacy of Different Fungicides in Pear Fruit: Structure-Diffusion-Activity Relationships.  Journal of Fungi,  (5): (547).  [PMID:35628802]
5. Xiao-Ting Zhen, Ya-Ling Yu, Min-Zhen Shi, Si-Chen Zhu, Tian-Ci Yan, Zi-Xuan Yue, Yu-Xin Gu, Hui Zheng, Jun Cao.  (2022)  Activated carbon derived from hawthorn kernel waste for rapid adsorption of fungicides.  Surfaces and Interfaces,  28  (101700).  [PMID:]
6. Yixia Yang, Behafarid Ghalandari, Liyun Lin, Xiao Sang, Wenqiong Su, Adeleh Divsalar, Xianting Ding.  (2022)  A turn-on fluorescence sensor based on Cu2+ modulated DNA-templated silver nanoclusters for glyphosate detection and mechanism investigation.  FOOD CHEMISTRY,  367  (130617).  [PMID:34352696]
7. Yong Han, Xie He, Weixia Yang, Xueli Luo, Ying Yu, Wenzhi Tang, Tianli Yue, Zhonghong Li.  (2021)  Ratiometric fluorescent sensing carbendazim in fruits and vegetables via its innate fluorescence coupling with UiO-67.  FOOD CHEMISTRY,  345  (128839).  [PMID:33340894]
8. Xinyue Zhao, Xiaomeng Zhang, Mingwei Qin, Yuzhu Song, Jinyang Zhang, Xueshan Xia, Xiuming Cui, Kai Gao, Qinqin Han.  (2021)  Determination of carbendazim by aptamer-based fluorescence resonance energy transfer (FRET).  ANALYTICAL LETTERS,  54  (13): (2198-2210).  [PMID:]
9. Yong Han, Weixia Yang, Xueli Luo, Xie He, Ying Yu, Chunhua Li, Wenzhi Tang, Tianli Yue, Zhonghong Li.  (2019)  Cu2+-Triggered Carbon Dots with Synchronous Response of Dual Emission for Ultrasensitive Ratiometric Fluorescence Determination of Thiophanate-Methyl Residues.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  67  (45): (12576–12583).  [PMID:31618026]
10. Shao Hua Lu, Sha Sha Li, Bo Yin, Jia Ying Mi, Hong Lin Zhai.  (2019)  The rapid quantitative analysis of three pesticides in cherry tomatoes and red grape samples with Tchebichef image moments.  FOOD CHEMISTRY,  290  (72).  [PMID:31000058]
11. Chuhong Zhu, Xiujuan Wang, Xiaofei Shi, Feng Yang, Guowen Meng, Qizhong Xiong, Yan Ke, Hua Wang, Yilin Lu, Nianqiang Wu.  (2017)  Detection of Dithiocarbamate Pesticides with a Spongelike Surface-Enhanced Raman Scattering Substrate Made of Reduced Graphene Oxide-Wrapped Silver Nanocubes.  ACS Applied Materials & Interfaces,  (45): (39618–39625).  [PMID:29058868]

References

1. Jie Zhao, Zi-Yu Li, Ting Cheng, Yan-Xin Chen, Cong Dai, Jia-Hui Zhu, Yu-Shen Liu, Lu-Liang Wang.  (2023)  Synthesis of magnetic covalent organic framework composites for effective extraction of benzimidazole fungicides from food samples.  MICROCHEMICAL JOURNAL,  195  (6): (109419).  [PMID:16491121]
2. Yu Ying, Huang Gengli, Luo Xueli, Lin Wanmei, Han Yong, Huang Jihong, Li Zhonghong.  (2022)  Carbon dots@Cu metal–organic frameworks hybrids for ratiometric fluorescent determination of pesticide thiophanate-methyl.  MICROCHIMICA ACTA,  189  (9): (1-9).  [PMID:35947204]
3. Xueli Luo, Gengli Huang, Yuchen Li, Jie Guo, Xiaokai Chen, Youwen Tan, Wenzhi Tang, Zhonghong Li.  (2022)  Dual-modes of ratiometric fluorescent and smartphone-integrated colorimetric detection of glyphosate by carbon dots encapsulated porphyrin metal–organic frameworks.  APPLIED SURFACE SCIENCE,  602  (154368).  [PMID:]
4. Gui-Yang Zhu, Ying Chen, Su-Yan Wang, Xin-Chi Shi, Daniela D. Herrera-Balandrano, Victor Polo, Pedro Laborda.  (2022)  Peel Diffusion and Antifungal Efficacy of Different Fungicides in Pear Fruit: Structure-Diffusion-Activity Relationships.  Journal of Fungi,  (5): (547).  [PMID:35628802]
5. Xiao-Ting Zhen, Ya-Ling Yu, Min-Zhen Shi, Si-Chen Zhu, Tian-Ci Yan, Zi-Xuan Yue, Yu-Xin Gu, Hui Zheng, Jun Cao.  (2022)  Activated carbon derived from hawthorn kernel waste for rapid adsorption of fungicides.  Surfaces and Interfaces,  28  (101700).  [PMID:]
6. Yixia Yang, Behafarid Ghalandari, Liyun Lin, Xiao Sang, Wenqiong Su, Adeleh Divsalar, Xianting Ding.  (2022)  A turn-on fluorescence sensor based on Cu2+ modulated DNA-templated silver nanoclusters for glyphosate detection and mechanism investigation.  FOOD CHEMISTRY,  367  (130617).  [PMID:34352696]
7. Yong Han, Xie He, Weixia Yang, Xueli Luo, Ying Yu, Wenzhi Tang, Tianli Yue, Zhonghong Li.  (2021)  Ratiometric fluorescent sensing carbendazim in fruits and vegetables via its innate fluorescence coupling with UiO-67.  FOOD CHEMISTRY,  345  (128839).  [PMID:33340894]
8. Xinyue Zhao, Xiaomeng Zhang, Mingwei Qin, Yuzhu Song, Jinyang Zhang, Xueshan Xia, Xiuming Cui, Kai Gao, Qinqin Han.  (2021)  Determination of carbendazim by aptamer-based fluorescence resonance energy transfer (FRET).  ANALYTICAL LETTERS,  54  (13): (2198-2210).  [PMID:]
9. Yong Han, Weixia Yang, Xueli Luo, Xie He, Ying Yu, Chunhua Li, Wenzhi Tang, Tianli Yue, Zhonghong Li.  (2019)  Cu2+-Triggered Carbon Dots with Synchronous Response of Dual Emission for Ultrasensitive Ratiometric Fluorescence Determination of Thiophanate-Methyl Residues.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  67  (45): (12576–12583).  [PMID:31618026]
10. Shao Hua Lu, Sha Sha Li, Bo Yin, Jia Ying Mi, Hong Lin Zhai.  (2019)  The rapid quantitative analysis of three pesticides in cherry tomatoes and red grape samples with Tchebichef image moments.  FOOD CHEMISTRY,  290  (72).  [PMID:31000058]
11. Chuhong Zhu, Xiujuan Wang, Xiaofei Shi, Feng Yang, Guowen Meng, Qizhong Xiong, Yan Ke, Hua Wang, Yilin Lu, Nianqiang Wu.  (2017)  Detection of Dithiocarbamate Pesticides with a Spongelike Surface-Enhanced Raman Scattering Substrate Made of Reduced Graphene Oxide-Wrapped Silver Nanocubes.  ACS Applied Materials & Interfaces,  (45): (39618–39625).  [PMID:29058868]

Solution Calculators