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Thioridazine hydrochloride - 98%, high purity , Serotonin 2c (5-HT2c) receptor antagonist, CAS No.130-61-0, Serotonin 2c (5-HT2c) receptor antagonist

  • ≥98%
Item Number
T166901
Grouped product items
SKUSizeAvailabilityPrice Qty
T166901-1g
1g
In stock
$16.90
T166901-5g
5g
In stock
$63.90
T166901-25g
25g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$222.90

Dopamine receptor antagonist

View related series
Pharmaceutical ingredients

Basic Description

SynonymsThioridazine hydrochloride|130-61-0|Thioridazine Hcl|Sonapax hydrochloride|Thioridazine chloride|Mellaril hydrochloride|Thioridazine.HCl|Melleril (tablet)|USAF SZ-B|Aldazine|USAF SZ-3|Thioridazine (hydrochloride)|Ridazine|UNII-4WCI67NK8M|EINECS 204-992-8|
Specifications & Purity98%
Storage TempProtected from light,Room temperature
Shipped InNormal
Action TypeANTAGONIST
Mechanism of actionSerotonin 2c (5-HT2c) receptor antagonist
Product Description

Thioridazine hydrochloride has been used as an intercalating agent for analyzing the integrity of double-stranded DNA (dsDNA) using square-wave voltammetry (SWV) techniques. Thioridazine hydrochloride has also been used as a positive control for the inhibition of hepatic enzyme cytochrome P4502D6 (CYP2D6) in human liver microsomes.

Names and Identifiers

IUPAC Name 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanylphenothiazine;hydrochloride
INCHI InChI=1S/C21H26N2S2.ClH/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23;/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3;1H
InChi Key NZFNXWQNBYZDAQ-UHFFFAOYSA-N
Canonical SMILES CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SC.Cl
Isomeric SMILES CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SC.Cl
WGK Germany 3
RTECS SP2275000
Alternate CAS 50-52-2
PubChem CID 66062
Molecular Weight 407.04

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
D2122037Certificate of AnalysisFeb 23, 2024 T166901
K2209072Certificate of AnalysisNov 10, 2022 T166901

Chemical and Physical Properties

SolubilitySoluble in water (75 mM), DMSO (100 mM), chloroform, ethanol, and methanol.
SensitivityLight & moisture sensitive
Melt Point(°C)161-163℃

Safety and Hazards(GHS)

Pictogram(s) GHS09,   GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

H400:Very toxic to aquatic life

H410:Very toxic to aquatic life with long lasting effects

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS SP2275000
Merck Index 9359

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