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| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | thonzylamine | 91-85-0 | Neohetramine | N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyrimidin-2-yl)ethane-1,2-diamine | Tonzilamine | Tonamil | NCI-C60708 | N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyrimidin-2-ylethane-1,2-diamine | 2-((2-(Dimethylamino)ethyl)(p-methoxyb |
|---|---|
| Specifications & Purity | ≥98% |
| Biochemical and Physiological Mechanisms | Thonzylamine (Neohetramine) is an antihistamine and anticholinergic drug. |
| Storage Temp | Store at -20°C,Argon charged |
| Shipped In | Ice chest + Ice pads |
| Product Description | Information Thonzylamine Thonzylamine (Neohetramine) is an antihistamine and anticholinergic drug. |
Associated Targets(Human)
HDAC6 Tclin Histone deacetylase 6 (0 Activities)
UGT1A4 Tbio UDP-glucuronosyltransferase 1-4 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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UGT1A4 Tbio UDP-glucuronosyltransferase 1A4 (288 Activities)
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Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SARS-CoV-2 (38078 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Names and Identifiers
| IUPAC Name | N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyrimidin-2-ylethane-1,2-diamine |
|---|---|
| INCHI | InChI=1S/C16H22N4O/c1-19(2)11-12-20(16-17-9-4-10-18-16)13-14-5-7-15(21-3)8-6-14/h4-10H,11-13H2,1-3H3 |
| InChi Key | GULNIHOSWFYMRN-UHFFFAOYSA-N |
| Canonical SMILES | CN(C)CCN(CC1=CC=C(C=C1)OC)C2=NC=CC=N2 |
| Isomeric SMILES | CN(C)CCN(CC1=CC=C(C=C1)OC)C2=NC=CC=N2 |
| PubChem CID | 5457 |
| Molecular Weight | 286.38 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 I2222111 | Certificate of Analysis | Jul 13, 2022 | T413469 |
| I2222112 | Certificate of Analysis | Jul 13, 2022 | T413469 |
| I2222113 | Certificate of Analysis | Jul 13, 2022 | T413469 |
| I2222114 | Certificate of Analysis | Jul 13, 2022 | T413469 |
Chemical and Physical Properties
| Solubility | Solubility (25°C) In vitro DMSO: 57 mg/mL (199.04 mM); Water: 57 mg/mL (199.04 mM); Ethanol: 13 mg/mL (45.39 mM); |
|---|---|
| Sensitivity | Easy to absorb moisture |
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P337+P313:IF eye irritation persists: Get medical advice/attention. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. |