| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab131013-10μl | 10μl | In stock | $46.90 | |
| Ab131013-50μl | 50μl | In stock | $139.90 | |
| Ab131013-100μl | 100μl | In stock | $219.90 | |
| Ab131013-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $729.90 |
mAb (H6); Mouse anti Human Thrombomodulin Antibody; WB; Unconjugated
| Product Name | Thrombomodulin Mouse mAb - Primary antibody, specific to Thrombomodulin, Mouse IgG1 |
|---|---|
| Synonyms | AHUS 6 antibody | AHUS6 antibody | BDCA 3 antibody | BDCA3 antibody | CD 141 antibody | CD141 antibody | CD141 antigen antibody | Fetomodulin antibody | Thbd antibody | THPH12 antibody | THRM antibody | Thrombomodulin antibody | TM antibody | TRBM_HUMAN a |
| Specifications & Purity | ExactAb™, Validated, Carrier Free, High performance, Lot by Lot |
| Host species | Mouse |
| Specificity | Thrombomodulin |
| Immunogen | Recombinant Thrombomodulin expressed in E.coli (AA 31-169). |
| Positive Control | WB: A431 cell lysate. |
| Conjugation | Unconjugated |
| Grade | Carrier Free, ExactAb™, High Performance, Validated |
| Note | 20μl卖完停产，不再备货 |
| Product Description | Mouse anti Human Thrombomodulin Antibody, Monoclonal (H6), could be used for WB and so on. |
| Isotype | Mouse IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified + Protein G purified |
| Form | Liquid |
| Concentration | Lot by Lot |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Thrombomodulin Mouse mAb (Ab131013) - Western Blot
All lanes: Thrombomodulin Mouse mAb (Ab131013) at 1/4000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution
Predicted band size: 60 kDa
Observed band size: 90 kDa
Exposure time: 100.0 s
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB |
0.01-2 µg/mL
|
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0404502 | Certificate of Analysis | Apr 15, 2024 | Ab131013 |
| ZJ24F0404503 | Certificate of Analysis | Apr 15, 2024 | Ab131013 |
| ZJ24F0404504 | Certificate of Analysis | Apr 15, 2024 | Ab131013 |
| 1. Deloukas P, Matthews LH, Ashurst J, Burton J, Gilbert JG, Jones M, Stavrides G, Almeida JP, Babbage AK, Bagguley CL, Bailey J, Barlow KF, Bates KN, Beard LM, Beare DM, Beasley OP, Bird CP, Blakey SE, Bridgeman AM, Brown AJ, Buck D, Burrill W, Butler AP, Carder C, Carter NP, Chapman JC, Clamp M, Clark G, Clark LN, Clark SY, Clee CM, Clegg S, Cobley VE, Collier RE, Connor R, Corby NR, Coulson A, Coville GJ, Deadman R, Dhami P, Dunn M, Ellington AG, Frankland JA, Fraser A, French L, Garner P, Grafham DV, Griffiths C, Griffiths MN, Gwilliam R, Hall RE, Hammond S, Harley JL, Heath PD, Ho S, Holden JL, Howden PJ, Huckle E, Hunt AR, Hunt SE, Jekosch K, Johnson CM, Johnson D, Kay MP, Kimberley AM, King A, Knights A, Laird GK, Lawlor S, Lehvaslaiho MH, Leversha M, Lloyd C, Lloyd DM, Lovell JD, Marsh VL, Martin SL, McConnachie LJ, McLay K, McMurray AA, Milne S, Mistry D, Moore MJ, Mullikin JC, Nickerson T, Oliver K, Parker A, Patel R, Pearce TA, Peck AI, Phillimore BJ, Prathalingam SR, Plumb RW, Ramsay H, Rice CM, Ross MT, Scott CE, Sehra HK, Shownkeen R, Sims S, Skuce CD, Smith ML, Soderlund C, Steward CA, Sulston JE, Swann M, Sycamore N, Taylor R, Tee L, Thomas DW, Thorpe A, Tracey A, Tromans AC, Vaudin M, Wall M, Wallis JM, Whitehead SL, Whittaker P, Willey DL, Williams L, Williams SA, Wilming L, Wray PW, Hubbard T, Durbin RM, Bentley DR, Beck S, Rogers J. (2001) The DNA sequence and comparative analysis of human chromosome 20.. Nature, 414 (6866): (865-71). [PMID:11780052] [10.1021/op500134e] |
| 2. McCachren, S S SS, Diggs, J J, Weinberg, J B JB and Dittman, W A WA.. (1991) Thrombomodulin expression by human blood monocytes and by human synovial tissue lining macrophages.. Blood, (15): [PMID:1660324] |
| 3. Jackman, R W RW, Beeler, D L DL, Fritze, L L, Soff, G G and Rosenberg, R D RD.. (1987) Human thrombomodulin gene is intron depleted: nucleic acid sequences of the cDNA and gene predict protein structure and suggest sites of regulatory control.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:2819876] |
| 4. Suzuki, K K and 9 more authors.. (1987) Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation.. The EMBO journal, [PMID:2820710] |
| 5. Wen, D Z DZ and 5 more authors.. (1987) Human thrombomodulin: complete cDNA sequence and chromosome localization of the gene.. Biochemistry, (14): [PMID:2822087] |
| 6. Shirai, T T and 7 more authors.. (1988) Gene structure of human thrombomodulin, a cofactor for thrombin-catalyzed activation of protein C.. Journal of biochemistry, [PMID:2836377] |
| 7. Adler, M M and 5 more authors.. (1995) The structure of a 19-residue fragment from the C-loop of the fourth epidermal growth factor-like domain of thrombomodulin.. The Journal of biological chemistry, (6): [PMID:7559494] |
| 8. Ohlin, A K AK and Marlar, R A RA.. (1995) The first mutation identified in the thrombomodulin gene in a 45-year-old man presenting with thromboembolic disease.. Blood, (15): [PMID:7811989] |
| 9. Srinivasan, J J and 5 more authors.. (1994) Thrombin-bound structure of an EGF subdomain from human thrombomodulin determined by transferred nuclear Overhauser effects.. Biochemistry, (22): [PMID:7947766] |
| 10. Gerlitz, B B and 5 more authors.. (1993) Identification of the predominant glycosaminoglycan-attachment site in soluble recombinant human thrombomodulin: potential regulation of functionality by glycosyltransferase competition for serine474.. The Biochemical journal, (1): [PMID:8216207] |
| 11. Yamamoto, S S and 5 more authors.. (1993) Urinary thrombomodulin, its isolation and characterization.. Journal of biochemistry, [PMID:8390446] |
| 12. Meininger, D P DP, Hunter, M J MJ and Komives, E A EA.. (1995) Synthesis, activity, and preliminary structure of the fourth EGF-like domain of thrombomodulin.. Protein science : a publication of the Protein Society, [PMID:8528067] |
| 13. Hrabal, R R, Komives, E A EA and Ni, F F.. (1996) Structural resiliency of an EGF-like subdomain bound to its target protein, thrombin.. Protein science : a publication of the Protein Society, [PMID:8745396] |
| 14. Norlund, L L, Holm, J J, Zöller, B B and Ohlin, A K AK.. (1997) A common thrombomodulin amino acid dimorphism is associated with myocardial infarction.. Thrombosis and haemostasis, [PMID:9157575] |
| 15. Ohlin, A K AK, Norlund, L L and Marlar, R A RA.. (1997) Thrombomodulin gene variations and thromboembolic disease.. Thrombosis and haemostasis, [PMID:9198186] |
| 16. Sampoli Benitez, B A BA, Hunter, M J MJ, Meininger, D P DP and Komives, E A EA.. (1997) Structure of the fifth EGF-like domain of thrombomodulin: An EGF-like domain with a novel disulfide-bonding pattern.. Journal of molecular biology, (7): [PMID:9367781] |
| 17. Doggen, C J CJ and 7 more authors.. (1998) A mutation in the thrombomodulin gene, 127G to A coding for Ala25Thr, and the risk of myocardial infarction in men.. Thrombosis and haemostasis, [PMID:9843165] |
| 18. Wu, K K KK and 6 more authors.. (2001) Thrombomodulin Ala455Val polymorphism and risk of coronary heart disease.. Circulation, (13): [PMID:11245641] |
| 19. Gresele, Paolo P and Agnelli, Giancarlo G.. (2002) Novel approaches to the treatment of thrombosis.. Trends in pharmacological sciences, [PMID:11804648] |
| 20. Faioni, Elena M EM, Franchi, Franca F, Castaman, Giancarlo G, Biguzzi, Eugenia E and Rodeghiero, Francesco F.. (2002) Mutations in the thrombomodulin gene are rare in patients with severe thrombophilia.. British journal of haematology, [PMID:12139752] |
| 21. Delvaeye, Mieke M and 12 more authors.. (2009) Thrombomodulin mutations in atypical hemolytic-uremic syndrome.. The New England journal of medicine, (23): [PMID:19625716] |
| 22. Maga, Tara K TK, Nishimura, Carla J CJ, Weaver, Amy E AE, Frees, Kathy L KL and Smith, Richard J H RJ.. (2010) Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome.. Human mutation, [PMID:20513133] |
| 23. Palayoor, Sanjeewani T and 6 more authors.. (2012) Gene expression profile of coronary artery cells treated with nonsteroidal anti-inflammatory drugs reveals off-target effects.. Journal of cardiovascular pharmacology, [PMID:22668799] |
| 24. Kawamoto, Eiji E and 6 more authors.. (2016) LFA-1 and Mac-1 integrins bind to the serine/threonine-rich domain of thrombomodulin.. Biochemical and biophysical research communications, (13): [PMID:27055590] |
