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Thromboxane B2 - ≥99%, high purity , CAS No.54397-85-2

≥99%

CAS#: 54397-85-2
Formula: C₂₀H₃₄O₆
Molecular Weight: 370.48
MDL number: MFCD00135258
PubChem CID: 5283137

Item Number

T134488

Grouped product items
SKU	Size	Availability	Price	Qty
T134488-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$480.90
T134488-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$3,433.90

Basic Description

Synonyms	TXB2 \| 5-Heptenoic acid, 7-[(2R,3S,4S)-tetrahydro-4,6-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-2H-pyran-3-yl]-, (5Z)-rel- \| Q3009646 \| TXB2 \| SR-01000946531 \| HY-113331 \| (5Z,13E,15S)-9alpha,11,15-trihydroxythromboxa-5,13-dien-1-oic acid \| NCGC0016130
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Prostaglandin derivative that is released during anaphylaxis; induces arterial contraction and platelet aggregation. Review of endogenous thromboxane B2 in risk analysis for development of thrombogenic disorders.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Note	卖完停产，不再备货
Product Description	TXB2 (Thromboxane B2) is a stable metabolite of thromboxane A2 in platelets which may be released during anaphylaxis. Reportedly possesses chemotactic properties. Often used to measure arachidonic acid metabolism. It is a prostaglandin derivative that is released during anaphylaxis, which induces arterial contraction and platelet aggregation by stimulating TP-α receptors. A stable metabolite of thromboxane B2.

Associated Targets(Human)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO2B1 Tchem Solute carrier organic anion transporter family member 2B1 (580 Activities)

Discover Target: SLCO2B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ABCC4 Tchem Multidrug resistance-associated protein 4 (785 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ABCC5 Tchem Multidrug resistance-associated protein 5 (50 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MRP3 Multidrug resistance associated protein (78 Activities)

Discover Target: MRP3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO3A1 Tbio Solute carrier organic anion transporter family member 3A1 (19 Activities)

Discover Target: SLCO3A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Abcc1 Multidrug resistance-associated protein 1 (42 Activities)

Discover Target: Abcc1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slco2a1 Solute carrier organic anion transporter family member 2A1 (47 Activities)

Discover Target: Slco2a1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	(Z)-7-[(2R,3S,4S)-4,6-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]oxan-3-yl]hept-5-enoic acid
INCHI	InChI=1S/C20H34O6/c1-2-3-6-9-15(21)12-13-18-16(17(22)14-20(25)26-18)10-7-4-5-8-11-19(23)24/h4,7,12-13,15-18,20-22,25H,2-3,5-6,8-11,14H2,1H3,(H,23,24)/b7-4-,13-12+/t15-,16-,17-,18+,20?/m0/s1
InChi Key	XNRNNGPBEPRNAR-JQBLCGNGSA-N
Canonical SMILES	CCCCCC(C=CC1C(C(CC(O1)O)O)CC=CCCCC(=O)O)O
Isomeric SMILES	CCCCC[C@@H](/C=C/[C@@H]1[C@H]([C@H](CC(O1)O)O)C/C=C\CCCC(=O)O)O
WGK Germany	3
PubChem CID	5283137
Molecular Weight	370.48

Certificates

Certificate of Analysis(COA)

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5 results found

Lot Number	Certificate Type	Date	Item
A2311006	Certificate of Analysis	Oct 11, 2024	T134488
A2306902	Certificate of Analysis	Oct 11, 2024	T134488
H2223507	Certificate of Analysis	Jun 20, 2024	T134488
A2306935	Certificate of Analysis	Nov 22, 2022	T134488
H2223508	Certificate of Analysis	Jun 20, 2022	T134488

Safety and Hazards(GHS)

Pictogram(s)	GHS08
Signal	Warning
Hazard Statements	H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice.
WGK Germany	3

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