Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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T580540-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $174.90 |
Selective GAT-1 inhibitor
Synonyms | tiagabine | 115103-54-3 | Gabitril | (R)-Tiagabine | Tiagabinum | Tiagabina | Gabatril | Tiagabinum [INN-Latin] | Tiagabina [INN-Spanish] | Tiagabine [INN] | Abbott-70569 | UNII-Z80I64HMNP | Z80I64HMNP | Tiagabine (INN) | ABT-569 FREE BASE | CHEBI:9586 | (-)-(R)-1-(4,4-Bis(3-methyl-2-th |
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Specifications & Purity | Moligand™, 10mM in DMSO |
Biochemical and Physiological Mechanisms | GABA uptake inhibitor, selective for GAT-1. Anticonvulsant in vivo . Also available in simple stock solutions add 1 ml of water to get an exact, ready-to-use concentration. |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Store at 2-8°C;Keep sealing condition ,The product can be stored for up to 24 months. |
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IUPAC Name | (3R)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-enyl]piperidine-3-carboxylic acid |
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INCHI | InChI=1S/C20H25NO2S2/c1-14-7-11-24-18(14)17(19-15(2)8-12-25-19)6-4-10-21-9-3-5-16(13-21)20(22)23/h6-8,11-12,16H,3-5,9-10,13H2,1-2H3,(H,22,23)/t16-/m1/s1 |
InChi Key | PBJUNZJWGZTSKL-MRXNPFEDSA-N |
Canonical SMILES | CC1=C(SC=C1)C(=CCCN2CCCC(C2)C(=O)O)C3=C(C=CS3)C |
Isomeric SMILES | CC1=C(SC=C1)C(=CCCN2CCC[C@H](C2)C(=O)O)C3=C(C=CS3)C |
PubChem CID | 60648 |
Molecular Weight | 375.55 |
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Solubility | Soluble in water to 25 mM and in 1 eq. NaOH to 100 mM |
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