Basic Description

Synonyms	tiapride \| 51012-32-9 \| Thiapride \| N-(2-(Diethylamino)ethyl)-2-methoxy-5-(methylsulfonyl)benzamide \| Thiapride; Tiapride \| N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide \| LAH70H9JPH \| Tiapride (INN) \| NSC-758225 \| N-(2-(Diethylamino)ethyl)-5-(methylsulfony
Shipped In	Normal
Action Type	ANTAGONIST
Mechanism of action	Dopamine D2 receptor antagonist

Product Properties

ALogP	0.9

Associated Targets(non-human)

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mc4r Melanocortin receptor 4 (1205 Activities)

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Ltc4s Leukotriene C4 synthase (1 Activities)

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Sigmar1 Sigma opioid receptor (160 Activities)

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Npy1r Neuropeptide Y receptor type 1 (8 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cckar Cholecystokinin A receptor (90 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pde4d Phosphodiesterase 4D (4 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nos2 Nitric oxide synthase, inducible (3573 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mapk1 MAP kinase ERK2 (650 Activities)

Discover Target: Mapk1

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Hdac6 Histone deacetylase 6 (222 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mmp9 Matrix metalloproteinase 9 (38 Activities)

Discover Target: Mmp9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 Activities)

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pfk 6-phospho-1-fructokinase (7870 Activities)

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Glra2 Glycine receptor (1745 Activities)

Discover Target: Glra2

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SARS-CoV-2 (38078 Activities)

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Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide
INCHI	InChI=1S/C15H24N2O4S/c1-5-17(6-2)10-9-16-15(18)13-11-12(22(4,19)20)7-8-14(13)21-3/h7-8,11H,5-6,9-10H2,1-4H3,(H,16,18)
InChi Key	JTVPZMFULRWINT-UHFFFAOYSA-N
Canonical SMILES	CCN(CC)CCNC(=O)C1=C(C=CC(=C1)S(=O)(=O)C)OC
Isomeric SMILES	CCN(CC)CCNC(=O)C1=C(C=CC(=C1)S(=O)(=O)C)OC
PubChem CID	5467
Molecular Weight	328.4

Certificates

Certificate of Analysis(COA)

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Safety and Hazards(GHS)

Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P301+P312:IF SWALLOWED: call a POISON CENTER/doctor/... IF you feel unwell.

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Tiapride hydrochloride , Dopamine D2 receptor antagonist, CAS No.51012-32-9, Dopamine D2 receptor antagonist