Tiliroside - ≥97%, high purity , CAS No.20316-62-5

Item Number

T138445

• Synonyms: HSDB 593 | 2-PROPENOIC ACID, 3-(4-HYDROXYPHENYL)-, 6'-ESTER WITH 3-(.BETA.-D-GLUCOPYRANOSYLOXY)-5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)-4H-1-BENZOPYRAN-4-ONE, (E)- | RONACARE TILIROSIDE | KAEMPFEROL 3-O-(6''-O-(E)-P-COUMAROYL)-.BETA.-D-GLUCOPYRANOSIDE | BDBM502
• Specifications & Purity: ≥97%
• Biochemical and Physiological Mechanisms: Anti-inflammatory and antioxidant. Reversible and competitive CYP inhibitor (IC50 values of 9, 10 and 12 μM for CYP3A4, CYP2C9 and CYP2C8, respectively). Inhibits NO, TNF-α and IL-12 production in activated macrophages.
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice

Product Description

Tiliroside, a flavanoid originally extracted from Magnoliafargesii, has been shown to have potent anti-complement activity on the classical pathway of the complement system. Additionally, this compound has been reported to have significant anti-proliferative effects. Furthermore, Tiliroside has been noted to strongly suppress serum GPT and GOT elevations in D-galactosamine (D-GaIN)/Lipopolysaccharide (sc-221854)(LPS)-induced liver injury in mice via inhibition of TNF-α production. Additionally, Tiliroside demonstrates antioxidant, anti-inflammatory, and scavenger properties through inhibition of enzymatic and non-enzymatic lipid peroxidation.