Tiliroside - ≥97%, high purity , CAS No.20316-62-5

Item Number

T138445

• Synonyms: Tiliroside | 20316-62-5 | Tribuloside | Trans-Tiliroside | 15M04TXR9M | CHEMBL266564 | [(2R,3S,4S,5R,6S)-6-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate | CHEBI:80944 | 22153-44-2 | 2-Propenoi
• Specifications & Purity: ≥97%
• Biochemical and Physiological Mechanisms: Anti-inflammatory and antioxidant. Reversible and competitive CYP inhibitor (IC50 values of 9, 10 and 12 μM for CYP3A4, CYP2C9 and CYP2C8, respectively). Inhibits NO, TNF-α and IL-12 production in activated macrophages.
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice

Product Description

Tiliroside, a flavanoid originally extracted from Magnoliafargesii, has been shown to have potent anti-complement activity on the classical pathway of the complement system. Additionally, this compound has been reported to have significant anti-proliferative effects. Furthermore, Tiliroside has been noted to strongly suppress serum GPT and GOT elevations in D-galactosamine (D-GaIN)/Lipopolysaccharide (sc-221854)(LPS)-induced liver injury in mice via inhibition of TNF-α production. Additionally, Tiliroside demonstrates antioxidant, anti-inflammatory, and scavenger properties through inhibition of enzymatic and non-enzymatic lipid peroxidation.