The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
Tiplaxtinin - ≥98%(HPLC), high purity , CAS No.393105-53-8
Plasminogen activator inhibitor-1 (PAI-1) inhibitor
Basic Description Synonyms PAI-039 | WAY-168039 | 2-[1-benzyl-5-[4-(trifluoromethoxy)phenyl]indol-3-yl]-2-oxoacetic acid | FT-0700303 | HY-15253 | Tiplasinin [USAN:INN] | A14190 | Tiplasinin (USAN) | 2-[1-benzyl-5-[4-(triluoromethoxy)phenyl]indol-3-yl]-2-oxoacetic acid | CHEBI:1777 Specifications & Purity ≥98%(HPLC) Biochemical and Physiological Mechanisms Plasminogen activator inhibitor-1 (PAI-1) inhibitor (IC50= 2.7μM). Induces vascular smooth muscle cell apoptosisin vitroand reduces carotid artery neointimal formation in a rat vascular injury model. Promotes thrombolysis in rat and dog models of acute ar Storage Temp Store at -20°C Shipped In Ice chest + Ice pads
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name 2-[1-benzyl-5-[4-(trifluoromethoxy)phenyl]indol-3-yl]-2-oxoacetic acid INCHI InChI=1S/C24H16F3NO4/c25-24(26,27)32-18-9-6-16(7-10-18)17-8-11-21-19(12-17)20(22(29)23(30)31)14-28(21)13-15-4-2-1-3-5-15/h1-12,14H,13H2,(H,30,31) InChi Key ODXQFEWQSHNQNI-UHFFFAOYSA-N Canonical SMILES C1=CC=C(C=C1)CN2C=C(C3=C2C=CC(=C3)C4=CC=C(C=C4)OC(F)(F)F)C(=O)C(=O)O Isomeric SMILES C1=CC=C(C=C1)CN2C=C(C3=C2C=CC(=C3)C4=CC=C(C=C4)OC(F)(F)F)C(=O)C(=O)O PubChem CID 6450819 Molecular Weight 439.38
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 43.94, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 43.94, Max Conc. mM: 100
Safety and Hazards(GHS) Hazard Statements H413: May cause long lasting harmful effects to aquatic life
Precautionary Statements P273: Avoid release to the environment.
P501: Dispose of contents/container to ...
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
J2116097