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Tirasemtiv (CK-2017357) - 10mM in DMSO, high purity , CAS No.1005491-05-3
Basic Description
| Synonyms | 1-(1-Ethylpropyl)-6-ethynyl-1,3-dihydro-2H-imidazo(4,5-b)pyrazin-2-one | AC-35962 | RSQGZEAXODVTOL-UHFFFAOYSA-N | 5GD84Y125G | Tirasemtiv [USAN:INN] | BCP27991 | 1-(1-Ethylpropyl)-6-ethynyl-1,3-dihydro-2H-imidazo[4,5-b]pyrazin-2-one | AKOS027250724 | MFCD |
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| Specifications & Purity | Moligand™, 10mM in DMSO |
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| Storage Temp | Store at -80°C |
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| Shipped In | Ice chest + Ice pads |
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| Grade | Moligand™ |
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| Product Description | Information Tirasemtiv (CK-2017357, CK-357) is a directfast skeletal muscle troponinactivator that sensitizes the sarcomere to calcium. |
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Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | 5-ethynyl-3-pentan-3-yl-1H-imidazo[4,5-b]pyrazin-2-one |
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| INCHI | InChI=1S/C12H14N4O/c1-4-8-7-13-10-11(14-8)16(12(17)15-10)9(5-2)6-3/h1,7,9H,5-6H2,2-3H3,(H,13,15,17) |
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| InChi Key | RSQGZEAXODVTOL-UHFFFAOYSA-N |
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| Canonical SMILES | CCC(CC)N1C2=NC(=CN=C2NC1=O)C#C |
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| Isomeric SMILES | CCC(CC)N1C2=NC(=CN=C2NC1=O)C#C |
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| Alternate CAS | 1005491-05-3 |
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| PubChem CID | 23729157 |
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| MeSH Entry Terms | CK-2017357;tirasemtiv |
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| Molecular Weight | 230.27 |
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