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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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T423632-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 |
TLR Inhibitors
Synonyms | TLR2-IN-C29 | 363600-92-4 | C29 | 3-[(2-hydroxy-3-methoxyphenyl)methylideneamino]-2-methylbenzoic acid | 3-((2-Hydroxy-3-methoxybenzylidene)amino)-2-methylbenzoic acid | 3-[(2-Hydroxy-3-methoxybenzylidene)amino]-2-methylbenzoic acid | 3-[[(2-hydroxy-3-methoxyphenyl)m |
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Specifications & Purity | 10mM in DMSO |
Biochemical and Physiological Mechanisms | TLR2-IN-C29 (C29) is a Toll-like receptor 2 (TLR2) inhibitor that inhibits TLR2/1 and TLR2/6 signaling. |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Product Description | Information TLR2-IN-C29 TLR2-IN-C29 (C29) is a Toll-like receptor 2 (TLR2) inhibitor that inhibits TLR2/1 and TLR2/6 signaling. Targets TLR2 |
ALogP | 3.284 |
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HBD Count | 1 |
Rotatable Bond | 4 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 3-[(2-hydroxy-3-methoxyphenyl)methylideneamino]-2-methylbenzoic acid |
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INCHI | InChI=1S/C16H15NO4/c1-10-12(16(19)20)6-4-7-13(10)17-9-11-5-3-8-14(21-2)15(11)18/h3-9,18H,1-2H3,(H,19,20) |
InChi Key | WTGMGRFVBFDHGQ-UHFFFAOYSA-N |
Canonical SMILES | CC1=C(C=CC=C1N=CC2=C(C(=CC=C2)OC)O)C(=O)O |
Isomeric SMILES | CC1=C(C=CC=C1N=CC2=C(C(=CC=C2)OC)O)C(=O)O |
PubChem CID | 3579893 |
Molecular Weight | 285.29 |
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DMSO(mg / mL) Max Solubility | 57 |
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DMSO(mM) Max Solubility | 199.796698096674 |
Water(mg / mL) Max Solubility | <1 |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. |