TLR2-IN-C29 - 10mM in DMSO, high purity , CAS No.363600-92-4

  • 10mM in DMSO
Item Number
T423632
Grouped product items
SKUSizeAvailabilityPrice Qty
T423632-1ml
1ml
Available within 8-12 weeks(?)
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$69.90

TLR Inhibitors

Basic Description

SynonymsTLR2-IN-C29 | 363600-92-4 | C29 | 3-[(2-hydroxy-3-methoxyphenyl)methylideneamino]-2-methylbenzoic acid | 3-((2-Hydroxy-3-methoxybenzylidene)amino)-2-methylbenzoic acid | 3-[(2-Hydroxy-3-methoxybenzylidene)amino]-2-methylbenzoic acid | 3-[[(2-hydroxy-3-methoxyphenyl)m
Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsTLR2-IN-C29 (C29) is a Toll-like receptor 2 (TLR2) inhibitor that inhibits TLR2/1 and TLR2/6 signaling.
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

Information

TLR2-IN-C29 TLR2-IN-C29 (C29) is a Toll-like receptor 2 (TLR2) inhibitor that inhibits TLR2/1 and TLR2/6 signaling.

Targets

TLR2

Product Properties

ALogP3.284
HBD Count1
Rotatable Bond4

Associated Targets(Human)

TLR2 Tchem Toll-like receptor 2 (975 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Tlr2 TLR2/TLR6 (253 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 3-[(2-hydroxy-3-methoxyphenyl)methylideneamino]-2-methylbenzoic acid
INCHI InChI=1S/C16H15NO4/c1-10-12(16(19)20)6-4-7-13(10)17-9-11-5-3-8-14(21-2)15(11)18/h3-9,18H,1-2H3,(H,19,20)
InChi Key WTGMGRFVBFDHGQ-UHFFFAOYSA-N
Canonical SMILES CC1=C(C=CC=C1N=CC2=C(C(=CC=C2)OC)O)C(=O)O
Isomeric SMILES CC1=C(C=CC=C1N=CC2=C(C(=CC=C2)OC)O)C(=O)O
PubChem CID 3579893
Molecular Weight 285.29

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

DMSO(mg / mL) Max Solubility57
DMSO(mM) Max Solubility199.796698096674
Water(mg / mL) Max Solubility<1

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

Related Documents

Solution Calculators