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TLX agonist 1 - 10mM in DMSO, high purity , CAS No.958323-31-4
Basic Description Specifications & Purity 10mM in DMSO Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Product Description Information
TLX agonist 1 (CCRP2, SUN23314) is a modulator oforphan nuclear receptor tailless (TLX, NR2E1)with EC50 of 1.0 μM and Kd of 650 nM. TLX agonist 1 (CCRP2, SUN23314) binds to recombinant TLX protein and enhances TLX transcriptional repressive activity.
Associated Targets(Human) Names and Identifiers IUPAC Name (4-benzhydrylpiperazin-1-yl)-(1,5-dimethylpyrazol-3-yl)methanone INCHI InChI=1S/C23H26N4O/c1-18-17-21(24-25(18)2)23(28)27-15-13-26(14-16-27)22(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-12,17,22H,13-16H2,1-2H3 InChi Key SSGJAUSSGPIZEE-UHFFFAOYSA-N Canonical SMILES CC1=CC(=NN1C)C(=O)N2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4 Isomeric SMILES CC1=CC(=NN1C)C(=O)N2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4 PubChem CID 2738508 Molecular Weight 374.5
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
H302: Harmful if swallowed
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P301+P312: IF SWALLOWED: call a POISON CENTER/doctor/... IF you feel unwell.
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