Tobramycin - Potency ≥900uG/mg,98%, high purity , CAS No.32986-56-4, Agonist of TAS2R20

16 Citations
Item Number
T100847
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T100847-200mg
200mg
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5g
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25g
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Ribosomal translation inhibitor

View related series
TAS2R20 Agonist

Basic Description

SynonymsTOBRADEX ST COMPONENT TOBRAMYCIN | TOBRAMYCIN (MART.) | TOBRAMYCIN [WHO-DD] | Tobramicina | Tobramycin,(S) | AT02 - Tobramycin | Spectrum_001072 | Nebicin | (2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl
Specifications & PurityMoligand™, ≥98%, Potency ≥900uG/mg
Biochemical and Physiological MechanismsPrimary Target myeloperoxidase-dependent oxidant cell injury.Inhibits ribosomal translation. Aminoglycoside antibiotic which binds 30S ribosomal subunit A, preventing functional protein production. Effective against gram-negative bacteria.
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of TAS2R20
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Tobramycin is an aminoglycoside antibiotic with similar structure to the kanamycins and gentamycins. It is useful for respiratory infection and cystic fibrosis research.
Tobramycin 是一种氨基糖苷类抗生素。

Product Properties

ALogP-6.2

Associated Targets(Human)

TAS2R20 Tchem Taste receptor type 2 member 20 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INSR Tclin Insulin receptor (5558 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR4 Tclin Serotonin 4 (5-HT4) receptor (2068 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR2 Tclin Estrogen receptor beta (9272 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYSLTR1 Tclin Cysteinyl leukotriene receptor 1 (2118 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ERBB2 Tclin Receptor protein-tyrosine kinase erbB-2 (7851 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM4 Tclin Muscarinic acetylcholine receptor M4 (6041 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM5 Tclin Muscarinic acetylcholine receptor M5 (4677 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sigmar1 Sigma opioid receptor (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rev Human immunodeficiency virus type 1 REV (13 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus sanguinis (314 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus pneumoniae (31063 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterococcus (1748 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Burkholderia cepacia (649 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pseudomonas putida (467 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Legionella pneumophila (143 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterobacter cloacae (7976 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Proteus vulgaris (5823 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Providencia rettgeri (925 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Salmonella typhimurium (15756 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus epidermidis (22802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus haemolyticus (1695 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus hominis (482 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter (437 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter calcoaceticus (618 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter sp. (243 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Moraxella catarrhalis (3334 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Enterobacteriaceae (669 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Citrobacter koseri (193 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Citrobacter freundii (1864 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella aerogenes (4963 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella oxytoca (929 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Morganella morganii (1291 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Proteus mirabilis (3894 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Providencia stuartii (425 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Salmonella (646 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Serratia marcescens (3237 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Shigella sonnei (625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aeromonas hydrophila (292 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Haemophilus influenzae (8812 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus warneri (476 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus salivarius (87 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus sp. (212 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Streptococcus mutans (2687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol
INCHI InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1
InChi Key NLVFBUXFDBBNBW-PBSUHMDJSA-N
Canonical SMILES C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(CC(C(O3)CN)O)N)N
Isomeric SMILES C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H](C[C@@H]([C@H](O3)CN)O)N)N
WGK Germany 2
RTECS WK2100000
PubChem CID 36294
Molecular Weight 467.51
Beilstein 1357507
Reaxy-Rn 1357507

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in water (94 mg/ml at 25 °C), ethanol (<1 mg/ml at 25 °C), DMSO (<1 mg/ml at 25 °C), methanol, and PBS (pH 7.2) (~10 mg/ml).,
SensitivityMoisture sensitive
Refractive Index143
Specific Rotation[α]143 ° (C=4, H2O)
Melt Point(°C)178°C

Safety and Hazards(GHS)

WGK Germany 2
RTECS WK2100000
Reaxy-Rn 1357507
Merck Index 9490

Related Documents

Citations of This Product

1. Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan.  (2024)  A highly stretchable, adhesive, and antibacterial hydrogel with chitosan and tobramycin as dynamic cross-linkers for treating the infected diabetic wound.  CARBOHYDRATE POLYMERS,  324  (121543).  [PMID:37985115]
2. Peng Li, Baihui Wang, Mengyao Qi, Huan Jiang, Yifei Li, Xia Zhang.  (2023)  Construction of aptamer sensor based on Au nanozymes for ultrasensitive SERS detection of tobramycin.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,  123  (105617).  [PMID:]
3. Jiawen Han, Yaru Ding, Xujuan Lv, Yuwei Zhang, Daoqing Fan.  (2023)  Integration of G-Quadruplex and Pyrene as a Simple and Efficient Ratiometric Fluorescent Platform That Programmed by Contrary Logic Pair for Highly Sensitive and Selective Coralyne (COR) Detection.  Biosensors-Basel,  13  (4): (489).  [PMID:37185564]
4. Jing Han, Pengfei Ma, Imran Mahmood Khan, Yin Zhang, Zhouping Wang.  (2023)  Study of binding mechanism of aptamer to kanamycin and the development of fluorescent aptasensor in milk detection.  TALANTA,  260  (124530).  [PMID:37116356]
5. Yuanyuan Zhang, Yuan Zhu, Tianjing Zeng, Lu Qiao, Mingjuan Zhang, Kexin Song, Nian Yin, Yani Tao, Yue Zhao, Chang Zhang, Yi Zhang.  (2023)  Self-powered photoelectrochemical aptasensor based on hollow tubular g-C3N4/Bi/BiVO4 for tobramycin detection.  ANALYTICA CHIMICA ACTA,  1250  (340951).  [PMID:36898823]
6. Xiaojie Wei, Chengbin Liu, Hehe Qin, Ziwei Ye, Xinru Liu, Boyang Zong, Zhuo Li, Shun Mao.  (2023)  Fast, specific, and ultrasensitive antibiotic residue detection by monolayer WS2-based field-effect transistor sensor.  JOURNAL OF HAZARDOUS MATERIALS,  443  (130299).  [PMID:36356526]
7. Chi Zhang, Gaiping Li, Baoxian Ye, Lina Zou, Weihang Wang, Yanli Ji.  (2022)  A reproducible electrochemical biosensor for tobramycin highly sensitive detection based on ExoIII-assisted nucleic acid circulation and CHA reaction.  MICROCHEMICAL JOURNAL,  183  (108040).  [PMID:]
8. Wenjuan Liu, Minglong Yan, Wenjie Zhao.  (2023)  Antibacterial-renew dual-function anti-biofouling strategy: Self-assembled Schiff-base metal complex coatings built from natural products.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  629  (496).  [PMID:36088695]
9. He Ziguo, Liu Jiaxu, Zhang Cheng, Sun Yudie, Chen Qian, Zhang Jian, Liu Shengjun, Yue Caibo, Ye Mingfu, Zhang Kui.  (2023)  Spectrally tunable humic acid–based carbon dots: a simple platform for metronidazole and ornidazole sensing in multiple real samples.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  415  (18): (4221-4232).  [PMID:36002744]
10. Lina Wang, Xiangbiao Zeng, Li Zhang, Ying Yu, Bixia Lin, Yumin Wang, Manli Guo, Yujuan Cao.  (2022)  Field-free electrochemical sensor: A novel inverted Y-type DNA conformation possessing specific self-transform capability for ultrasensitive determination of tetracycline.  MICROCHEMICAL JOURNAL,  181  (107724).  [PMID:]
11. Xiaofei Liao, Mengyan Li, Li Zou.  (2022)  Target-induced activation of DNAzyme for highly sensitive colorimetric detection of bleomycin via DNA scission.  RSC Advances,  12  (29): (18296-18300).  [PMID:35799941]
12. Lishan Zhang, Zujie Yao, Huamei Tang, Qingli Song, Huanhuan Song, Jindong Yao, Zhen Li, Xiaofang Xie, Yuexu Lin, Xiangmin Lin.  (2022)  The Lysine Acetylation Modification in the Porin Aha1 of Aeromonas hydrophila Regulates the Uptake of Multidrug Antibiotics.  MOLECULAR & CELLULAR PROTEOMICS,  21  (9):   [PMID:35605723]
13. Jingjing Li, Long Jiang, Xu Wang, Zhixue Zhu, Qingxin Zhang, Su Liu, Yu Wang, Jiadong Huang.  (2022)  Ultrasensitive electrochemical aptasensor based on palindromic sequence mediated bidirectional SDA and a DNAzyme walker for kanamycin detection.  NEW JOURNAL OF CHEMISTRY,  46  (21): (10394-10401).  [PMID:]
14. Xiuxiu Yang, Zhongqiang Yang.  (2022)  Simple and Rapid Detection of Ibuprofen─A Typical Pharmaceuticals and Personal Care Products─by a Liquid Crystal Aptasensor.  LANGMUIR,  38  (1): (282–288).  [PMID:34955019]
15. Kecheng Quan, Zexin Zhang, Yijin Ren, Henk J. Busscher, Henny C. van der Mei, Brandon W. Peterson.  (2021)  On-demand pulling-off of magnetic nanoparticles from biomaterial surfaces through implant-associated infectious biofilms for enhanced antibiotic efficacy.  Materials Science & Engineering C-Materials for Biological Applications,  131  (112526).  [PMID:34857305]
16. Jinmei Li, Dong Wang, Yang Wang, Baoyu Gao, Zhining Wang.  (2021)  Surface Modification of Reverse Osmosis Membranes for Enhanced Boron Removal and Fouling Resistance.  ACS ES&T Water,  (10): (2284–2292).  [PMID:]

References

1. Haas W, Pillar CM, Zurenko GE, Lee JC, Brunner LS, Morris TW.  (2009)  Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria..  Antimicrob Agents Chemother,  53  (8): (3552-60).  [PMID:19506065]
2. Lopez-Novoa JM, Quiros Y, Vicente L, Morales AI, Lopez-Hernandez FJ.  (2011)  New insights into the mechanism of aminoglycoside nephrotoxicity: an integrative point of view..  Kidney Int,  79  (1): (33-45).  [PMID:20861826]
3. Wargo KA, Edwards JD.  (2014)  Aminoglycoside-induced nephrotoxicity..  J Pharm Pract,  27  (6): (573-7).  [PMID:25199523]
4. Pazhayattil GS, Shirali AC.  (2014)  Drug-induced impairment of renal function..  Int J Nephrol Renovasc Dis,  (3): (457-68).  [PMID:25540591]
5. Beznosková P et al..  (2019)  Yeast applied readthrough inducing system (YARIS): an invivo assay for the comprehensive study of translational readthrough..  Nucleic Acids Res,  47  (12): (6339-6350).  [PMID:31069379]
6. Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan.  (2024)  A highly stretchable, adhesive, and antibacterial hydrogel with chitosan and tobramycin as dynamic cross-linkers for treating the infected diabetic wound.  CARBOHYDRATE POLYMERS,  324  (121543).  [PMID:37985115]
7. Peng Li, Baihui Wang, Mengyao Qi, Huan Jiang, Yifei Li, Xia Zhang.  (2023)  Construction of aptamer sensor based on Au nanozymes for ultrasensitive SERS detection of tobramycin.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,  123  (105617).  [PMID:]
8. Jiawen Han, Yaru Ding, Xujuan Lv, Yuwei Zhang, Daoqing Fan.  (2023)  Integration of G-Quadruplex and Pyrene as a Simple and Efficient Ratiometric Fluorescent Platform That Programmed by Contrary Logic Pair for Highly Sensitive and Selective Coralyne (COR) Detection.  Biosensors-Basel,  13  (4): (489).  [PMID:37185564]
9. Jing Han, Pengfei Ma, Imran Mahmood Khan, Yin Zhang, Zhouping Wang.  (2023)  Study of binding mechanism of aptamer to kanamycin and the development of fluorescent aptasensor in milk detection.  TALANTA,  260  (124530).  [PMID:37116356]
10. Yuanyuan Zhang, Yuan Zhu, Tianjing Zeng, Lu Qiao, Mingjuan Zhang, Kexin Song, Nian Yin, Yani Tao, Yue Zhao, Chang Zhang, Yi Zhang.  (2023)  Self-powered photoelectrochemical aptasensor based on hollow tubular g-C3N4/Bi/BiVO4 for tobramycin detection.  ANALYTICA CHIMICA ACTA,  1250  (340951).  [PMID:36898823]
11. Xiaojie Wei, Chengbin Liu, Hehe Qin, Ziwei Ye, Xinru Liu, Boyang Zong, Zhuo Li, Shun Mao.  (2023)  Fast, specific, and ultrasensitive antibiotic residue detection by monolayer WS2-based field-effect transistor sensor.  JOURNAL OF HAZARDOUS MATERIALS,  443  (130299).  [PMID:36356526]
12. Chi Zhang, Gaiping Li, Baoxian Ye, Lina Zou, Weihang Wang, Yanli Ji.  (2022)  A reproducible electrochemical biosensor for tobramycin highly sensitive detection based on ExoIII-assisted nucleic acid circulation and CHA reaction.  MICROCHEMICAL JOURNAL,  183  (108040).  [PMID:]
13. Wenjuan Liu, Minglong Yan, Wenjie Zhao.  (2023)  Antibacterial-renew dual-function anti-biofouling strategy: Self-assembled Schiff-base metal complex coatings built from natural products.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  629  (496).  [PMID:36088695]
14. He Ziguo, Liu Jiaxu, Zhang Cheng, Sun Yudie, Chen Qian, Zhang Jian, Liu Shengjun, Yue Caibo, Ye Mingfu, Zhang Kui.  (2023)  Spectrally tunable humic acid–based carbon dots: a simple platform for metronidazole and ornidazole sensing in multiple real samples.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  415  (18): (4221-4232).  [PMID:36002744]
15. Lina Wang, Xiangbiao Zeng, Li Zhang, Ying Yu, Bixia Lin, Yumin Wang, Manli Guo, Yujuan Cao.  (2022)  Field-free electrochemical sensor: A novel inverted Y-type DNA conformation possessing specific self-transform capability for ultrasensitive determination of tetracycline.  MICROCHEMICAL JOURNAL,  181  (107724).  [PMID:]
16. Xiaofei Liao, Mengyan Li, Li Zou.  (2022)  Target-induced activation of DNAzyme for highly sensitive colorimetric detection of bleomycin via DNA scission.  RSC Advances,  12  (29): (18296-18300).  [PMID:35799941]
17. Lishan Zhang, Zujie Yao, Huamei Tang, Qingli Song, Huanhuan Song, Jindong Yao, Zhen Li, Xiaofang Xie, Yuexu Lin, Xiangmin Lin.  (2022)  The Lysine Acetylation Modification in the Porin Aha1 of Aeromonas hydrophila Regulates the Uptake of Multidrug Antibiotics.  MOLECULAR & CELLULAR PROTEOMICS,  21  (9):   [PMID:35605723]
18. Jingjing Li, Long Jiang, Xu Wang, Zhixue Zhu, Qingxin Zhang, Su Liu, Yu Wang, Jiadong Huang.  (2022)  Ultrasensitive electrochemical aptasensor based on palindromic sequence mediated bidirectional SDA and a DNAzyme walker for kanamycin detection.  NEW JOURNAL OF CHEMISTRY,  46  (21): (10394-10401).  [PMID:]
19. Xiuxiu Yang, Zhongqiang Yang.  (2022)  Simple and Rapid Detection of Ibuprofen─A Typical Pharmaceuticals and Personal Care Products─by a Liquid Crystal Aptasensor.  LANGMUIR,  38  (1): (282–288).  [PMID:34955019]
20. Kecheng Quan, Zexin Zhang, Yijin Ren, Henk J. Busscher, Henny C. van der Mei, Brandon W. Peterson.  (2021)  On-demand pulling-off of magnetic nanoparticles from biomaterial surfaces through implant-associated infectious biofilms for enhanced antibiotic efficacy.  Materials Science & Engineering C-Materials for Biological Applications,  131  (112526).  [PMID:34857305]
21. Jinmei Li, Dong Wang, Yang Wang, Baoyu Gao, Zhining Wang.  (2021)  Surface Modification of Reverse Osmosis Membranes for Enhanced Boron Removal and Fouling Resistance.  ACS ES&T Water,  (10): (2284–2292).  [PMID:]

Solution Calculators