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Tolbutamide - ≥99%, high purity , Sulfonylurea receptor 1, Kir6.2 blocker, CAS No.64-77-7, Sulfonylurea receptor 1, Kir6.2 blocker

Specifications & Purity:  ≥99%
Item Number
T129578
Grouped product items
SKUSizeAvailabilityPrice Qty
T129578-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$105.90
T129578-10g
10g
In stock
$190.90
T129578-25g
25g
In stock
$429.90
T129578-100g
100g
In stock
$1,545.90
T129578-250g
250g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$3,477.90
T129578-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$6,259.90

K + channel blocker

Basic Description

Synonymstolbutamide|64-77-7|Orinase|Arkozal|Willbutamide|Butamide|Diabetamid|Ipoglicone|Glyconon|Rastinon|Tolbutamid|Aglicid|Artosin|Diaben|Tolumid|1-Butyl-3-tosylurea|Diasulfon|Artozin|Butamid|Diabetol|Diabuton|Dirastan|Dolipol|Mobenol|Oterben|Pramidex|Tolbusal|
Specifications & Purity≥99%
Storage TempStore at -20°C
Shipped InDry ice
Action TypeBLOCKER, CHANNEL BLOCKER, INHIBITOR
Mechanism of actionSulfonylurea receptor 1, Kir6.2 blocker

Product Properties

ALogP2.3

Associated Targets

KCNJ8 Tbio ATP-sensitive inward rectifier potassium channel 8 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNJ11 Tclin ATP-sensitive inward rectifier potassium channel 11 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 1-butyl-3-(4-methylphenyl)sulfonylurea
INCHI InChI=1S/C12H18N2O3S/c1-3-4-9-13-12(15)14-18(16,17)11-7-5-10(2)6-8-11/h5-8H,3-4,9H2,1-2H3,(H2,13,14,15)
InChi Key JLRGJRBPOGGCBT-UHFFFAOYSA-N
Canonical SMILES CCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)C
Isomeric SMILES CCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)C
PubChem CID 5505
Molecular Weight 270.35

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

12 results found

Lot NumberCertificate TypeDateItem
F2101045Certificate of AnalysisMar 13, 2023 T129578
A2304570Certificate of AnalysisNov 18, 2022 T129578
A2304572Certificate of AnalysisNov 18, 2022 T129578
A2304582Certificate of AnalysisNov 18, 2022 T129578
A2304599Certificate of AnalysisNov 18, 2022 T129578
A2304600Certificate of AnalysisNov 18, 2022 T129578
A2304602Certificate of AnalysisNov 18, 2022 T129578
E2310033Certificate of AnalysisNov 18, 2022 T129578
E2407015Certificate of AnalysisNov 18, 2022 T129578
J2310195Certificate of AnalysisNov 18, 2022 T129578
G2219213Certificate of AnalysisJul 23, 2022 T129578
H1401054Certificate of AnalysisMay 06, 2022 T129578

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Chemical and Physical Properties

SolubilitySoluble in DMSO or 100% ethanol; insoluble in water.
Melt Point(°C)127 °C

Safety and Hazards(GHS)

Related Documents

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Reviews

Customer Reviews

References

1. Rehmann H.  (2012)  Epac2: a sulfonylurea receptor?.  Biochem Soc Trans,  40  (1): (6-10).  [PMID:22260657]
2. González BJ et al..  (2022)  Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency..  Commun Biol,  (779).  [PMID:35918471]

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