Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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T129355-1g | 1g | In stock | $65.90 | |
T129355-5g | 5g | In stock | $155.90 | |
T129355-25g | 25g | In stock | $702.90 |
Synonyms | NSC 233648 | m,N-Dimethylthiocarbanilic acid O-2-naphthyl ester | Ting antifungal cream | Fungistop | Tinactin powder | Tolnaftate (USAN:USP:INN:BAN:JAN) | Tolnaftate Oil | Tolnaftate serum | Fungus Relief | Naphthiomate-T | meijerantifungal | Naphthiomat |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | It prevents ergosterol biosynthesis by inhibiting squalene epoxidase. It has also been reported to distort the hyphae and to stunt mycelial growth in susceptible organisms. Tolnaftate inhibits biosynthesis of aflatoxin. |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Product Description | Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent. |
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IUPAC Name | O-naphthalen-2-yl N-methyl-N-(3-methylphenyl)carbamothioate |
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INCHI | InChI=1S/C19H17NOS/c1-14-6-5-9-17(12-14)20(2)19(22)21-18-11-10-15-7-3-4-8-16(15)13-18/h3-13H,1-2H3 |
InChi Key | FUSNMLFNXJSCDI-UHFFFAOYSA-N |
Canonical SMILES | CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2 |
Isomeric SMILES | CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2 |
PubChem CID | 5510 |
Molecular Weight | 307.41 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
E2014058 | Certificate of Analysis | Apr 13, 2022 | T129355 |
Solubility | DMSO 62 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
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Sensitivity | Heat sensitive |
Melt Point(°C) | 110-113°C |
Pictogram(s) | GHS09, GHS07 |
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Signal | Warning |
Hazard Statements | H319:Causes serious eye irritation H411:Toxic to aquatic life with long lasting effects H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P391:Collect spillage. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. |
Merck Index | 9519 |