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Toremifene - 98%, high purity , CAS No.89778-26-7

  • Moligand™
  • ≥98%
Item Number
T126260
Grouped product items
SKUSizeAvailabilityPrice Qty
T126260-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$50.90
T126260-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$160.90
T126260-500mg
500mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$720.90

Competitive, irreversible estrogen biosynthesis inhibitor

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Maxi Cl⁻ Activator

Basic Description

Synonymstoremifene|89778-26-7|Farestone|Z-Toremifene|Toremifeno|Toremifenum|Chlortamoxifen|Toremifenum [Latin]|GTx 006|Toremiphene|GTx-006|UNII-7NFE54O27T|Toremifene (INN)|7NFE54O27T|CCRIS 8745|CHEBI:9635|(E)-Toremifene|J33.157K|(Z)-2-(4-(4-Chloro-1,2-diphenyl-1-
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsIC50 Value: 1±0.3μM. Toremifene is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis and other adverse effects resulting from ADT in men with prostate cancer [1]. in vitro: The gro
Storage TempProtected from light,Store at -20°C,Argon charged
Shipped InIce chest + Ice pads
GradeMoligand™
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets

EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DHCR24 Tchem Delta(24)-sterol reductase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

EBP Tchem 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GMNN Tbio Geminin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABCB1 Tchem Multidrug resistance protein 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PMP22 Tbio Peripheral myelin protein 22 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

LMNA Tbio Prelamin-A/C 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR6 Tchem 5-hydroxytryptamine receptor 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine
INCHI InChI=1S/C26H28ClNO/c1-28(2)19-20-29-24-15-13-23(14-16-24)26(22-11-7-4-8-12-22)25(17-18-27)21-9-5-3-6-10-21/h3-16H,17-20H2,1-2H3/b26-25-
InChi Key XFCLJVABOIYOMF-QPLCGJKRSA-N
Canonical SMILES CN(C)CCOC1=CC=C(C=C1)C(=C(CCCl)C2=CC=CC=C2)C3=CC=CC=C3
Isomeric SMILES CN(C)CCOC1=CC=C(C=C1)/C(=C(/CCCl)\C2=CC=CC=C2)/C3=CC=CC=C3
PubChem CID 3005573
Molecular Weight 405.96

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
C2320121Certificate of AnalysisDec 21, 2022 T126260
C2320176Certificate of AnalysisDec 21, 2022 T126260
C2320182Certificate of AnalysisDec 21, 2022 T126260

Chemical and Physical Properties

Solubility25°C: DMSO 120mg/mL ;Water <1mg/mL; Ethanol <1mg/mL
Sensitivitylight sensitive

Related Documents

References

1. Price N, Sartor O, Hutson T, Mariani S.  (2005)  Role of 5a-reductase inhibitors and selective estrogen receptor modulators as potential chemopreventive agents for prostate cancer..  Clin Prostate Cancer,  (4): (211-4).  [PMID:15882476]

Solution Calculators