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trans-2-Hydroxycinnamic acid - 97%, high purity , CAS No.614-60-8

≥97%

CAS#: 614-60-8
Formula: C₉H₈O₃
Molecular Weight: 164.16
Beilstein Registry Number: 1100900
EC Number: 210-386-4
MDL number: MFCD00004379
PubChem CID: 637540

Item Number

H113425

Grouped product items
SKU	Size	Availability	Price
H113425-5g	5g	In stock	$21.90
H113425-25g	25g	In stock	$58.90
H113425-100g	100g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$212.90

View related series

Carbonyl compound carboxylic acid

Basic Description

Synonyms	2-Hydroxycinnamic acid \| 614-60-8 \| trans-2-Hydroxycinnamic acid \| o-Coumaric acid \| 2-Coumaric acid \| trans-o-Coumaric acid \| trans-o-Hydroxycinnamic acid \| 583-17-5 \| (E)-o-Hydroxycinnamic acid \| 3-(2-hydroxyphenyl)acrylic acid \| 2-Coumarate \| 2-Hydroxycinnamate \| (2E)-3-(2-hy
Specifications & Purity	≥97%
Shipped In	Normal

Associated Targets(Human)

CA2 Tclin Carbonic anhydrase II (17698 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TYR Tclin Tyrosinase (717 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

XDH Tclin Xanthine dehydrogenase (1038 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CA3 Tclin Carbonic anhydrase III (753 Activities)

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CA6 Tclin Carbonic anhydrase VI (993 Activities)

Discover Target: CA6

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CA1 Tclin Carbonic anhydrase I (13240 Activities)

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CA5B Tclin Carbonic anhydrase VB (957 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CA5A Tclin Carbonic anhydrase VA (1168 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CA14 Tclin Carbonic anhydrase XIV (1305 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NFKB1 Tclin Nuclear factor NF-kappa-B p105 subunit (1459 Activities)

Discover Target: NFKB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CA12 Tclin Carbonic anhydrase XII (6231 Activities)

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CA9 Tclin Carbonic anhydrase IX (8255 Activities)

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SLC22A8 Tclin Solute carrier family 22 member 8 (241 Activities)

Discover Target: SLC22A8

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CDK4 Tclin Cyclin-dependent kinase 4/cyclin D1 (2340 Activities)

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Associated Targets(non-human)

Ca7 Carbonic anhydrase VII (3 Activities)

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Ca13 Carbonic anhydrase XIII (322 Activities)

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CA4 Carbonic anhydrase IV (1713 Activities)

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Cryz Quinone oxidoreductase (288 Activities)

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Hcar2 Hydroxycarboxylic acid receptor 2 (55 Activities)

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Ralstonia solanacearum (520 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mycobacterium tuberculosis (203094 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mycolicibacterium smegmatis (8003 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Trypanosoma brucei brucei (13300 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Leishmania amazonensis (3813 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Leishmania donovani (89745 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Trypanosoma cruzi (99888 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Trypanosoma brucei rhodesiense (7991 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RAW264.7 (28094 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RBL-2H3 (1162 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BV-2 (3710 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Ca15 Carbonic anhydrase 15 (173 Activities)

Discover Target: Ca15

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Bursaphelenchus xylophilus (372 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mycobacterium tuberculosis variant bovis BCG (1626 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DHODH Dihydroorotate dehydrogenase (fumarate) (195 Activities)

Discover Target: DHODH

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	(E)-3-(2-hydroxyphenyl)prop-2-enoic acid
INCHI	InChI=1S/C9H8O3/c10-8-4-2-1-3-7(8)5-6-9(11)12/h1-6,10H,(H,11,12)/b6-5+
InChi Key	PMOWTIHVNWZYFI-AATRIKPKSA-N
Canonical SMILES	C1=CC=C(C(=C1)C=CC(=O)O)O
Isomeric SMILES	C1=CC=C(C(=C1)/C=C/C(=O)O)O
WGK Germany	3
RTECS	GD9090000
PubChem CID	637540
UN Number	2811
Molecular Weight	164.16
Beilstein	1100900
Reaxy-Rn	1100900

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot Number	Certificate Type	Date	Item
I1606044	Certificate of Analysis	Apr 02, 2024	H113425
I1917035	Certificate of Analysis	Jul 10, 2023	H113425
G2319468	Certificate of Analysis	Jan 05, 2022	H113425

Chemical and Physical Properties

Solubility	Soluble in water (partly).
Melt Point(°C)	217°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	GD9090000
Reaxy-Rn	1100900

Citations of This Product

1. Yifan Lin, Shaohua Li, Tao Chen, Yanxiang Lin, Zaixing Cheng, Lin Ni, Jin-jian Lu, Mingqing Huang. (2023) Phytochemical compositions and biological activities of the branches and leaves of Ormosia hosiei Hemsl. et Wils.. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 226 (115238). [PMID:36645985]
2. Xuejing Wang, Yinyan Yuan, YiXiao Sun, Xue Liu, Mingze Ma, Renyin Zhang, Feng Shi. (2022) One-step facile preparation of carbon dots with high fluorescence quantum yield and application in rapid latent fingerprint detection. RSC Advances, 12 (42): (27199-27205). [PMID:36276032]

References

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18. Yuan Gao,Meng Wang,Nan Jiang,Yao Wang,Xiaoyuan Feng. (2019-01-11) Use of ultra-performance liquid chromatography-tandem mass spectrometry on sweet cherries to determine phenolic compounds in peel and flesh.. Journal of the science of food and agriculture, 99 ((7)): (3555-3562). [PMID:30628083]
19. Yan Zhang,Sam K C Chang. (2019-01-20) Comparative studies on ACE inhibition, degree of hydrolysis, antioxidant property and phenolic acid composition of hydrolysates derived from simulated in vitro gastrointestinal proteolysis of three thermally treated legumes.. Food chemistry, 281 (154-162). [PMID:30658742]
20. Andrei Mocan,Alina Diuzheva,Sabin Bădărău,Cadmiel Moldovan,Vasil Andruch,Simone Carradori,Cristina Campestre,Angela Tartaglia,Marta De Simone,Dan Vodnar,Matteo Tiecco,Raimondo Germani,Gianina Crișan,Marcello Locatelli. (2019-03-31) Liquid Phase and Microwave-Assisted Extractions for Multicomponent Phenolic Pattern Determination of Five Romanian Galium Species Coupled with Bioassays.. Molecules (Basel, Switzerland), 24 ((7)): [PMID:30925810]
21. Jia-Qi Hu,Qi Qi,Yan-Ling Zhao,Xiao-Ming Tian,Hai Lu,Ying Gai,Xiang-Ning Jiang. (2019-05-06) Unraveling the impact of Pto4CL1 regulation on the cell wall components and wood properties of perennial transgenic Populus tomentosa.. Plant physiology and biochemistry : PPB, 139 (672-680). [PMID:31054469]
22. Baqia Al Mughairy,Haider A J Al-Lawati,FakhrEldin O Suliman. (2019-06-07) Investigating the impact of metal ions and 3D printed droplet microfluidics chip geometry on the luminol‑potassium periodate chemiluminescence system for estimating total phenolic content in olive oil.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 221 (117182-117182). [PMID:31170602]
23. Dilek Demirbuker Kavak,Bilge Akdeniz. (2019-06-20) Sorbus umbellata (Desf.) Fritsch var. umbellata Leaves: Optimization of Extraction Conditions and Investigation Antimicrobial, Cytotoxic, and β-Glucuronidase Inhibitory Potential.. Plant foods for human nutrition (Dordrecht, Netherlands), 74 ((3)): (364-369). [PMID:31214936]
24. Armaghan Shafaei,Kevin Croft,Jonathan Hodgson,Mary C Boyce. (2019-07-12) Simultaneous quantitative analysis of polyphenolic compounds in human plasma by liquid chromatography tandem mass spectrometry.. Journal of separation science, 42 ((18)): (2909-2921). [PMID:31293055]
25. Rocío Moreno-González,M Emília Juan,Joana M Planas. (2019-08-17) Table olive polyphenols: A simultaneous determination by liquid chromatography-mass spectrometry.. Journal of chromatography. A, 1609 (460434-460434). [PMID:31416621]
26. Fernanda F Juliano,José Fernando R Alvarenga,Rosa Maria Lamuela-Raventos,Adna P Massarioli,Liziane M Lima,Roseane C Santos,Severino M Alencar. (2019-10-12) Polyphenol analysis using high-resolution mass spectrometry allows differentiation of drought tolerant peanut genotypes.. Journal of the science of food and agriculture, 100 ((2)): (721-731). [PMID:31602648]
27. Paula Mendonça Leite,Ana Paula Nader Miranda,Juliana Mendes Amorim,Rita Carolina Figueiredo Duarte,Suzan Kelly Vilela Bertolucci,Maria das Graças Carvalho,Rachel Oliveira Castilho. (2019-12-10) In Vitro Anticoagulant Activity of Mikania laevigata: Deepening the Study of the Possible Interaction Between Guaco and Anticoagulants.. Journal of cardiovascular pharmacology, 74 ((6)): (574-583). [PMID:31815870]
28. Xinjing Dou,Liangxiao Zhang,Xiao Wang,Ruinan Yang,Xuefang Wang,Fei Ma,Li Yu,Jin Mao,Hui Li,Xiupin Wang,Peiwu Li. (2020-03-04) Identification and Validation of Metabolic Markers for Adulteration Detection of Edible Oils Using Metabolic Networks.. Metabolites, 10 ((3)): [PMID:32121379]
29. Maša Islamčević Razboršek,Milena Ivanović,Peter Krajnc,Mitja Kolar. (2020-04-05) Choline Chloride Based Natural Deep Eutectic Solvents as Extraction Media for Extracting Phenolic Compounds from Chokeberry (Aronia Melanocarpa).. Molecules (Basel, Switzerland), 25 ((7)): [PMID:32244757]
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31. Catherine P Bondonno,Nicola P Bondonno,Sujata Shinde,Armaghan Shafaei,Mary C Boyce,Ewald Swinny,Steele R Jacob,Kevin Lacey,Richard J Woodman,Kevin D Croft,Michael J Considine,Jonathan M Hodgson. (2020-08-04) Phenolic composition of 91 Australian apple varieties: towards understanding their health attributes.. Food & function, 11 ((8)): (7115-7125). [PMID:32744555]
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33. Jelena Torić,Monika Barbarić,Stanko Uršić,Cvijeta Jakobušić Brala,Ana Karković Marković,Maja Zebić Avdičević,Đani Benčić. (2020-09-27) Antique Traditional Practice: Phenolic Profile of Virgin Olive Oil Obtained from Fruits Stored in Seawater.. Foods (Basel, Switzerland), 9 ((10)): [PMID:32977641]
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39. Sullivan Renouard,Cyrielle Corbin,Samantha Drouet,Barbara Medvedec,Joël Doussot,Cyril Colas,Benoit Maunit,Avninder S Bhambra,Eric Gontier,Nathalie Jullian,François Mesnard,Michèle Boitel,Bilal Haider Abbasi,Randolph R J Arroo,Eric Lainé,Christophe Hano. (2018-03-29) Investigation of Linum flavum (L.) Hairy Root Cultures for the Production of Anticancer Aryltetralin Lignans.. International journal of molecular sciences, 19 ((4)): [PMID:29587452]
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41. Joselin Aguiar,João L Gonçalves,Vera L Alves,José S Câmara. (2020-04-15) Chemical Fingerprint of Free Polyphenols and Antioxidant Activity in Dietary Fruits and Vegetables Using a Non-Targeted Approach Based on QuEChERS Ultrasound-Assisted Extraction Combined with UHPLC-PDA.. Antioxidants (Basel, Switzerland), 9 ((4)): [PMID:32283793]
42. Hosam O Elansary,Agnieszka Szopa,Paweł Kubica,Halina Ekiert,Fahed A Al-Mana,Mohammed A Al-Yafrsi. (2020-07-28) Antioxidant and Biological Activities of Acacia saligna and Lawsonia inermis Natural Populations.. Plants (Basel, Switzerland), 9 ((7)): [PMID:32709119]
43. Sridevi Muralidharan,Yan Yee Poon,Graeme C Wright,Paul A Haynes,Nanju A Lee. (2020-07-28) Quantitative proteomics analysis of high and low polyphenol expressing recombinant inbred lines (RILs) of peanut (Arachis hypogaea L.).. Food chemistry, 334 (127517-127517). [PMID:32711266]
44. Joham Sarfraz Ali,Hammad Saleem,Abdul Mannan,Gokhan Zengin,Mohamad Fawzi Mahomoodally,Marcello Locatelli,Syafiq Asnawi Zainal Abidin,Nafees Ahemad,Muhammad Zia. (2020-10-18) Metabolic fingerprinting, antioxidant characterization, and enzyme-inhibitory response of Monotheca buxifolia (Falc.) A. DC. extracts.. BMC complementary medicine and therapies, 20 ((1)): (313-313). [PMID:33066787]
45. Wei-Tang Chang,Shih-Chien Huang,Hsin-Lin Cheng,Shiuan-Chih Chen,Chin-Lin Hsu. (2021-03-07) Rutin and Gallic Acid Regulates Mitochondrial Functions via the SIRT1 Pathway in C2C12 Myotubes.. Antioxidants (Basel, Switzerland), 10 ((2)): [PMID:33668647]
46. Yifan Lin, Shaohua Li, Tao Chen, Yanxiang Lin, Zaixing Cheng, Lin Ni, Jin-jian Lu, Mingqing Huang. (2023) Phytochemical compositions and biological activities of the branches and leaves of Ormosia hosiei Hemsl. et Wils.. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 226 (115238). [PMID:36645985]
47. Xuejing Wang, Yinyan Yuan, YiXiao Sun, Xue Liu, Mingze Ma, Renyin Zhang, Feng Shi. (2022) One-step facile preparation of carbon dots with high fluorescence quantum yield and application in rapid latent fingerprint detection. RSC Advances, 12 (42): (27199-27205). [PMID:36276032]

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