Grouped product items

SKU

Size

Availability

Price

Qty

H100569-5g

Available within 4-8 weeks(?)

$16.90

H100569-10g

10g

In stock

$29.90

H100569-25g

25g

Available within 4-8 weeks(?)

$65.90

H100569-50g

50g

In stock

$117.90

H100569-100g

100g

In stock

$211.90

Basic Description

Synonyms	Cinnamic acid, 3-hydroxy- \| trans-3-Hydroxycinnamic acid, 99% \| 3-(3-hydroxyphenyl)-2-propenoic acid \| 3-(3-Hydroxyphenyl)acrylsaeure \| bmse000093 \| Q6712039 \| (E)-3-(3-hydroxyphenyl)prop-2-enoic acid \| LS-13594 \| HY-113357 \| (2E)-3-(3-hydroxyphenyl)prop-
Specifications & Purity	≥99%
Shipped In	Normal

Associated Targets(Human)

APP Tclin Amyloid-beta A4 protein (8510 Activities)

Discover Target: APP

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SRR Tbio Serine racemase (249 Activities)

Discover Target: SRR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC16A1 Tchem Monocarboxylate transporter 1 (146 Activities)

Discover Target: SLC16A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DAO Tchem D-amino-acid oxidase (802 Activities)

Discover Target: DAO

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DDO Tchem D-aspartate oxidase (120 Activities)

Discover Target: DDO

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC16A7 Tchem Monocarboxylate transporter 2 (11 Activities)

Discover Target: SLC16A7

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Cryz Quinone oxidoreductase (288 Activities)

Discover Target: Cryz

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HD1 Histone deacetylase (38 Activities)

Discover Target: HD1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hcar2 Hydroxycarboxylic acid receptor 2 (55 Activities)

Discover Target: Hcar2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAL62 Alpha-glucosidase MAL62 (106 Activities)

Discover Target: MAL62

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mycobacterium tuberculosis (203094 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mycolicibacterium smegmatis (8003 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Trypanosoma brucei brucei (13300 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RAW264.7 (28094 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RBL-2H3 (1162 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Radish (446 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mycobacterium tuberculosis variant bovis BCG (1626 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488190844
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488190844
IUPAC Name	(E)-3-(3-hydroxyphenyl)prop-2-enoic acid
INCHI	InChI=1S/C9H8O3/c10-8-3-1-2-7(6-8)4-5-9(11)12/h1-6,10H,(H,11,12)/b5-4+
InChi Key	KKSDGJDHHZEWEP-SNAWJCMRSA-N
Canonical SMILES	C1=CC(=CC(=C1)O)C=CC(=O)O
Isomeric SMILES	C1=CC(=CC(=C1)O)/C=C/C(=O)O
WGK Germany	3
PubChem CID	637541
Molecular Weight	164.16
Beilstein	2084229
Reaxy-Rn	2084229

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number	Certificate Type	Date	Item
B1928086	Certificate of Analysis	Dec 12, 2022	H100569
D2415417	Certificate of Analysis	Dec 09, 2021	H100569

Chemical and Physical Properties

Solubility	Soluble in ether, methanol, benzene, ethanol
Melt Point(°C)	196°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
Reaxy-Rn	2084229

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Li Min, Wang Yayao, Xiao Jianxing, Yan Xingfu, Liu Bingru. (2023) Allelopathic inhibition effects and mechanism of phenolic acids to Microcystis aeruginosa. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 30 (15): (45388-45397). [PMID:36705822] [10.1007/s11356-022-24992-5]
2. Zhi-Ming Wu, Yu Cao, Jin-Han Guo, Xiu-Qin Fang, Cheng-Mei Liu. (2022) Bio-based poly(vinyl benzoxazine) derived from 3-hydroxycinnamic acid— An intrinsically green flame-retardant polymer free of both halogen and phosphorus. REACTIVE & FUNCTIONAL POLYMERS, 181 (105430). [PMID:] [10.1016/j.reactfunctpolym.2022.105430]
3. Teng Sun, Haiping Zhang, Zhe Dong, Zengshe Liu, Mingming Zheng. (2020) Ultrasonic-promoted enzymatic preparation, identification and multi-active studies of nature-identical phenolic acid glycerol derivatives. RSC Advances, 10 (19): (11139-11147). [PMID:35495308] [10.1039/C9RA09830E]

References

1. J Cabanes,F García-Carmona,F García-Cánovas,J L Iborra,J A Lozano. (1984-10-23) Kinetic study on the slow inhibition of epidermis tyrosinase by m-coumaric acid.. Biochimica et biophysica acta, 790 ((2)): (101-107). [PMID:6435675]
2. van Veldhoven JP, Blad CC, Artsen CM, Klopman C, Wolfram DR, Abdelkadir MJ, Lane JR, Brussee J, Ijzerman AP. (2011) Structure-activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A).. Bioorg Med Chem Lett, 21 (9): (2736-9). [PMID:21167710] [10.1021/op500134e]
3. Seigo Baba,Naomi Osakabe,Midori Natsume,Junji Terao. (2004-05-04) Orally administered rosmarinic acid is present as the conjugated and/or methylated forms in plasma, and is degraded and metabolized to conjugated forms of caffeic acid, ferulic acid and m-coumaric acid.. Life sciences, 75 ((2)): (165-178). [PMID:15120569]
4. Yutaka Konishi,Shoko Kobayashi. (2004-10-14) Microbial metabolites of ingested caffeic acid are absorbed by the monocarboxylic acid transporter (MCT) in intestinal Caco-2 cell monolayers.. Journal of agricultural and food chemistry, 52 ((21)): (6418-6424). [PMID:15479001]
5. Alfonso Pérez-Garrido,Aliuska Morales Helguera,Adela Abellán Guillén,M Natália D S Cordeiro,Amalio Garrido Escudero. (2008-12-06) Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.. Bioorganic & medicinal chemistry, 17 ((2)): (896-904). [PMID:19056282]
6. Ashley A Reinke,Han Yiau Seh,Jason E Gestwicki. (2009-07-31) A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.. Bioorganic & medicinal chemistry letters, 19 ((17)): (4952-4957). [PMID:19640715]
7. Hnin Thanda Aung,Tadashi Furukawa,Toshiaki Nikai,Masatake Niwa,Yoshiaki Takaya. (2011-03-11) Contribution of cinnamic acid analogues in rosmarinic acid to inhibition of snake venom induced hemorrhage.. Bioorganic & medicinal chemistry, 19 ((7)): (2392-2396). [PMID:21388814]
8. Mattia Gasperotti,Domenico Masuero,Graziano Guella,Fulvio Mattivi,Urska Vrhovsek. (2014-07-26) Development of a targeted method for twenty-three metabolites related to polyphenol gut microbial metabolism in biological samples, using SPE and UHPLC-ESI-MS/MS.. Talanta, 128 (221-230). [PMID:25059152]
9. Miriam Martínez-Huélamo,Sara Tulipani,Ramón Estruch,Elvira Escribano,Montserrat Illán,Dolores Corella,Rosa M Lamuela-Raventós. (2014-12-04) The tomato sauce making process affects the bioaccessibility and bioavailability of tomato phenolics: a pharmacokinetic study.. Food chemistry, 173 (864-872). [PMID:25466100]
10. Janique Vandal,Mamdouh M Abou-Zaid,Garry Ferroni,Leo G Leduc. (2015-02-24) Antimicrobial activity of natural products from the flora of Northern Ontario, Canada.. Pharmaceutical biology, 53 ((6)): (800-806). [PMID:25697605]
11. Mattia Gasperotti,Sabina Passamonti,Federica Tramer,Domenico Masuero,Graziano Guella,Fulvio Mattivi,Urska Vrhovsek. (2015-04-22) Fate of microbial metabolites of dietary polyphenols in rats: is the brain their target destination?. ACS chemical neuroscience, 6 ((8)): (1341-1352). [PMID:25891864]
12. María L Salum,Pau Arroyo Mañez,F Javier Luque,Rosa Erra-Balsells. (2015-04-29) Combined experimental and computational investigation of the absorption spectra of E- and Z-cinnamic acids in solution: The peculiarity of Z-cinnamics.. Journal of photochemistry and photobiology. B, Biology, 148 (128-135). [PMID:25911983]
13. Jhih-Jia Jhang,Chi-Cheng Lu,Cheng-Ying Ho,Yu-Ting Cheng,Gow-Chin Yen. (2015-08-04) Protective Effects of Catechin against Monosodium Urate-Induced Inflammation through the Modulation of NLRP3 Inflammasome Activation.. Journal of agricultural and food chemistry, 63 ((33)): (7343-7352). [PMID:26234731]
14. Fernanda F Juliano,José Fernando R Alvarenga,Rosa Maria Lamuela-Raventos,Adna P Massarioli,Liziane M Lima,Roseane C Santos,Severino M Alencar. (2019-10-12) Polyphenol analysis using high-resolution mass spectrometry allows differentiation of drought tolerant peanut genotypes.. Journal of the science of food and agriculture, 100 ((2)): (721-731). [PMID:31602648]
15. Ji-Eun Lee,Seon-Mi Seo,Min-Jung Huh,Sung-Chan Lee,Il-Kwon Park. (2020-07-28) Reactive oxygen species mediated-antifungal activity of cinnamon bark (Cinnamomum verum) and lemongrass (Cymbopogon citratus) essential oils and their constituents against two phytopathogenic fungi.. Pesticide biochemistry and physiology, 168 (104644-104644). [PMID:32711777]
16. Antonia Nostro,Angela Filocamo,Annalisa Giovannini,Stefania Catania,Chiara Costa,Andreana Marino,Giuseppe Bisignano. (2011-10-22) Antimicrobial activity and phenolic content of natural site and micropropagated Limonium avei (De Not.) Brullo & Erben plant extracts.. Natural product research, 26 ((22)): (2132-2136). [PMID:22014177]
17. Alexis Eugene,Catherine Lapierre,John Ralph. (2020-12-12) Improved analysis of arabinoxylan-bound hydroxycinnamate conjugates in grass cell walls.. Biotechnology for biofuels, 13 ((1)): (202-202). [PMID:33303001]
18. Li Min, Wang Yayao, Xiao Jianxing, Yan Xingfu, Liu Bingru. (2023) Allelopathic inhibition effects and mechanism of phenolic acids to Microcystis aeruginosa. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 30 (15): (45388-45397). [PMID:36705822] [10.1007/s11356-022-24992-5]
19. Zhi-Ming Wu, Yu Cao, Jin-Han Guo, Xiu-Qin Fang, Cheng-Mei Liu. (2022) Bio-based poly(vinyl benzoxazine) derived from 3-hydroxycinnamic acid— An intrinsically green flame-retardant polymer free of both halogen and phosphorus. REACTIVE & FUNCTIONAL POLYMERS, 181 (105430). [PMID:] [10.1016/j.reactfunctpolym.2022.105430]
20. Teng Sun, Haiping Zhang, Zhe Dong, Zengshe Liu, Mingming Zheng. (2020) Ultrasonic-promoted enzymatic preparation, identification and multi-active studies of nature-identical phenolic acid glycerol derivatives. RSC Advances, 10 (19): (11139-11147). [PMID:35495308] [10.1039/C9RA09830E]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

trans-3-Hydroxycinnamic acid - 99%, high purity , CAS No.14755-02-3

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Citations of This Product

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

SKU	Size	Availability	Price
H100569-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$16.90
H100569-10g	10g	In stock	$29.90
H100569-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$65.90
H100569-50g	50g	In stock	$117.90
H100569-100g	100g	In stock	$211.90