Determine the necessary mass, volume, or concentration for preparing a solution.
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Basic Description
| Synonyms | trans-Aconitic acid | 4023-65-8 | (E)-prop-1-ene-1,2,3-tricarboxylic acid | trans-Aconitate | (E)-1-Propene-1,2,3-tricarboxylic acid | ACONITIC ACID | (E)-Aconitic acid | Aconitic acid, (E)- | ACONITIC ACID, TRANS | (1E)-prop-1-ene-1,2,3-tricarboxylic acid | Aconitic acid, t |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Antimicrobial agent that blocks the transformation of Leishmania donovani amastigotes to prostigotes. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Trans-Aconitic acid is inhibitor of the tricarboxylic acid cycle。 Trans-Aconitic acid was used in synthesis of aconitate esters. It may be used for cross-linking polyvinyl alcohol film for preparing composite nanofiltration membranes. |
Associated Targets(Human)
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
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ACLY Tclin ATP-citrate synthase (168 Activities)
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CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
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CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
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CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
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CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
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KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
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Associated Targets(non-human)
fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | (E)-prop-1-ene-1,2,3-tricarboxylic acid |
|---|---|
| INCHI | InChI=1S/C6H6O6/c7-4(8)1-3(6(11)12)2-5(9)10/h1H,2H2,(H,7,8)(H,9,10)(H,11,12)/b3-1+ |
| InChi Key | GTZCVFVGUGFEME-HNQUOIGGSA-N |
| Canonical SMILES | C(C(=CC(=O)O)C(=O)O)C(=O)O |
| Isomeric SMILES | C(/C(=C\C(=O)O)/C(=O)O)C(=O)O |
| WGK Germany | 3 |
| PubChem CID | 444212 |
| Molecular Weight | 174.11 |
| Beilstein | 1725830 |
| Reaxy-Rn | 1725830 |
Certificates
Certificate of Analysis(COA)
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Chemical and Physical Properties
| Melt Point(°C) | 190°C |
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Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 3 |
| Reaxy-Rn | 1725830 |
Related Documents
Citations of This Product
| 1. Qiang Chen, Lili Zheng, Xiaoqin Deng, Menghan Zhang, Wendi Han, Zhengjun Huang, Chenfang Miao, Shaohuang Weng. (2023) A fluorescence biosensor for tyrosinase activity analysis based on silicon-doped carbon quantum dots. CHEMICAL & PHARMACEUTICAL BULLETIN, (4): [PMID:37704432] |
| 2. Kui Kang, Mengyi Zhang, Lei Yue, Weiwen Chen, Yangshuo Dai, Kai Lin, Kai Liu, Jun Lv, Zhanwen Guan, Shi Xiao, Wenqing Zhang. (2023) Oxalic Acid Inhibits Feeding Behavior of the Brown Planthopper via Binding to Gustatory Receptor Gr23a. Cells, 12 (5): (771). [PMID:36899907] |
| 3. Zhang Haijuan, Qiao Xin, Cai Tianpei, Chen Jia, Li Zhan, Qiu Hongdeng. (2017) Preparation and characterization of carbon dot-decorated silica stationary phase in deep eutectic solvents for hydrophilic interaction chromatography. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 409 (9): (2401-2410). [PMID:28084509] |
References
| 1. Qiang Chen, Lili Zheng, Xiaoqin Deng, Menghan Zhang, Wendi Han, Zhengjun Huang, Chenfang Miao, Shaohuang Weng. (2023) A fluorescence biosensor for tyrosinase activity analysis based on silicon-doped carbon quantum dots. CHEMICAL & PHARMACEUTICAL BULLETIN, (4): [PMID:37704432] |
| 2. Kui Kang, Mengyi Zhang, Lei Yue, Weiwen Chen, Yangshuo Dai, Kai Lin, Kai Liu, Jun Lv, Zhanwen Guan, Shi Xiao, Wenqing Zhang. (2023) Oxalic Acid Inhibits Feeding Behavior of the Brown Planthopper via Binding to Gustatory Receptor Gr23a. Cells, 12 (5): (771). [PMID:36899907] |
| 3. Zhang Haijuan, Qiao Xin, Cai Tianpei, Chen Jia, Li Zhan, Qiu Hongdeng. (2017) Preparation and characterization of carbon dot-decorated silica stationary phase in deep eutectic solvents for hydrophilic interaction chromatography. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 409 (9): (2401-2410). [PMID:28084509] |