(-)-trans-H₂-PAT , CAS No.T611206, Antagonist of H 1 receptor

Item Number
T611206
Grouped product items
SKUSizeAvailabilityPrice Qty
T611206-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$680.90
T611206-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,020.90

Basic Description

Synonyms1-Phenyl-3-dimethylamino-1,2,3,4-tetrahydronaphthalene | PDSP2_000944 | (2R,4S)-N,N-dimethyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-2-amine | trans-4-phenyl-2-N,N-dimethylaminotetralin | SCHEMBL3755417 | trans-PAT | (-)-trans-H2-PAT | N,N-dimethyl-4-phenyl
Specifications & PurityMoligand™
GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of H 1 receptor

Associated Targets(Human)

HRH3 Tclin Histamine H3 receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HRH1 Tclin Histamine H1 receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences
Serotonin 2a (5-HT2a) receptor antagonistANTAGONISTALA224Serotonin 2a (5-HT2a) receptorSINGLE PROTEINHomo sapiens

FDA: [1]


Serotonin 2a (5-HT2a) receptor antagonistANTAGONISTALA224Serotonin 2a (5-HT2a) receptorSINGLE PROTEINHomo sapiens

PubMed: [1] , [2]


Wikipedia: [1] , [2]


Serotonin 2a (5-HT2a) receptor antagonistANTAGONISTALA224Serotonin 2a (5-HT2a) receptorSINGLE PROTEINHomo sapiens

ISBN: [1]


PubMed: [1]


Wikipedia: [1]


Serotonin 2a (5-HT2a) receptor antagonistANTAGONISTALA224Serotonin 2a (5-HT2a) receptorSINGLE PROTEINHomo sapiens

DailyMed: [1]


ISBN: [1]


PubMed: [1]


Wikipedia: [1]


Serotonin 2a (5-HT2a) receptor antagonistANTAGONISTALA224Serotonin 2a (5-HT2a) receptorSINGLE PROTEINHomo sapiens

PubMed: [1] , [2]


Serotonin 2a (5-HT2a) receptor antagonistANTAGONISTALA224Serotonin 2a (5-HT2a) receptorSINGLE PROTEINHomo sapiens

ISBN: [1]


PubMed: [1]


Wikipedia: [1]


Serotonin 2a (5-HT2a) receptor antagonistANTAGONISTALA224Serotonin 2a (5-HT2a) receptorSINGLE PROTEINHomo sapiens

FDA: [1]


Serotonin 2a (5-HT2a) receptor antagonistANTAGONISTALA224Serotonin 2a (5-HT2a) receptorSINGLE PROTEINHomo sapiens

ISBN: [1]


PubMed: [1]


Wikipedia: [1]


Serotonin 2a (5-HT2a) receptor antagonistANTAGONISTALA224Serotonin 2a (5-HT2a) receptorSINGLE PROTEINHomo sapiens

ISBN: [1]


PubMed: [1]


Wikipedia: [1] , [2]


Serotonin 2a (5-HT2a) receptor antagonistANTAGONISTALA224Serotonin 2a (5-HT2a) receptorSINGLE PROTEINHomo sapiens

DailyMed: [1]


Names and Identifiers

IUPAC Name (2R,4S)-N,N-dimethyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-2-amine
INCHI InChI=1S/C18H21N/c1-19(2)16-12-15-10-6-7-11-17(15)18(13-16)14-8-4-3-5-9-14/h3-11,16,18H,12-13H2,1-2H3/t16-,18-/m0/s1
InChi Key DXJUCAUQIHNOAF-WMZOPIPTSA-N
Canonical SMILES CN([C@H]1Cc2ccccc2[C@@H](C1)c1ccccc1)C
Isomeric SMILES CN(C)[C@@H]1C[C@H](C2=CC=CC=C2C1)C3=CC=CC=C3
PubChem CID 10015055

Certificates

C of A & Other Certificates

Related Documents

Solution Calculators