Skip to the beginning of the images gallery

Tribromomethane - 99%,contains 1-3% ethanol as stabilizer, high purity , CAS No.75-25-2

8 Citations

≥99%
contains 1-3% ethanol as stabilizer

CAS#: 75-25-2
Formula: CHBr₃
Molecular Weight: 252.73
Beilstein Registry Number: 1731048
EC Number: 200-854-6
MDL number: MFCD00000128
PubChem CID: 5558

Item Number

T108556

Grouped product items
SKU	Size	Availability	Price
T108556-10g	10g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$15.90
T108556-50g	50g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$60.90
T108556-250g	250g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$274.90

View related series

Non heterocyclic block Spectroscopic reagent

Basic Description

Synonyms	AKOS009031540 \| Q409799 \| S0653 \| DB03054 \| FT-0623471 \| DTXCID401374 \| RCRA waste number U225 \| AT27291 \| Methyl tribromide \| Tribromomethane 100 microg/mL in Methanol \| Bromoform [UN2515] [Poison] \| BROMOFORM [WHO-DD] \| CHBr3 \| J-519947 \| Methenyl trib
Specifications & Purity	≥99%, contains 1-3% ethanol as stabilizer
Storage Temp	Protected from light
Shipped In	Normal
Product Description	Bromoform (Tribromomethane) was used in the synthesis of α-tribromomethylated N-sulfonylamines.

Associated Targets(Human)

TP53 Tchem Cellular tumor antigen p53 (0 Activities)

Discover Target: TP53

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CXCL8 Tchem Interleukin-8 (0 Activities)

Discover Target: CXCL8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CXCL8 Tchem Interleukin-8 (642 Activities)

Discover Target: CXCL8

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TP53 Tchem Cellular tumor antigen p53 (48468 Activities)

Discover Target: TP53

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	bromoform
INCHI	InChI=1S/CHBr3/c2-1(3)4/h1H
InChi Key	DIKBFYAXUHHXCS-UHFFFAOYSA-N
Canonical SMILES	C(Br)(Br)Br
Isomeric SMILES	C(Br)(Br)Br
WGK Germany	3
RTECS	PB5600000
PubChem CID	5558
UN Number	2515
Packing Group	III
Molecular Weight	252.73
Beilstein	1731048
Reaxy-Rn	1731048

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot Number	Certificate Type	Date	Item
K2130154	Certificate of Analysis	Jun 14, 2023	T108556
K2130156	Certificate of Analysis	Jun 14, 2023	T108556
K2123005	Certificate of Analysis	Jun 14, 2023	T108556
H2206367	Certificate of Analysis	May 12, 2023	T108556
H2206368	Certificate of Analysis	May 12, 2023	T108556
G2102270	Certificate of Analysis	Feb 10, 2023	T108556
G2102271	Certificate of Analysis	Feb 10, 2023	T108556
K2017068	Certificate of Analysis	Aug 09, 2022	T108556
J1819022	Certificate of Analysis	May 06, 2022	T108556

Chemical and Physical Properties

Solubility	Solubility in water: Practically Insoluble; Degree of Solubility in water: 1 g/l 20 °C
Sensitivity	Light sensitive.
Refractive Index	1.5976
Boil Point(°C)	148-150°C
Melt Point(°C)	8-9°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS09, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H331:Toxic if inhaled H411:Toxic to aquatic life with long lasting effects H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P316:Get emergency medical help immediately.
WGK Germany	3
RTECS	PB5600000
Reaxy-Rn	1731048
Class	6.1
Merck Index	1420

Alternative Products

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Jiaben Zhong, Hangyan Zhang, Yina Cai, Xiuping Chen, Zhiyuan Fang, Dun Deng. (2023) Rapid and visual detection of dichloroacetonitrile in water. ANALYST, 148 (21): (5390-5394). [PMID:37750310] [10.1039/D3AN01282D]
2. Ximiao Zhu, Chenhui Hao, Mengze Zhang, Bingyan Lan. (2023) Enhanced Adsorption of Bromoform onto Microplastic Polyethylene Terephthalate Exposed to Ozonation and Chlorination. MOLECULES, 28 (1): (259). [PMID:36615452] [10.3390/molecules28010259]
3. Yang Guo, Huachao Li, Guofeng Qiu, Yan Li, Yanjie Niu, Jie Xu, Wenke Jia, Yixin Zhang, Jianjun Wu, Fanhui Guo. (2023) Processing of coal gasification fine slag by different physical separation methods: Fate of typical heavy metals and comparison analysis on products. SEPARATION AND PURIFICATION TECHNOLOGY, 306 (122675). [PMID:] [10.1016/j.seppur.2022.122675]
4. Pamphile Ndagijimana, Xuejiao Liu, Qingxin Xu, Zhiwei Li, Beibei Pan, Xu Liao, Yin Wang. (2022) Nanoscale zero-valent iron/silver@activated carbon-reduced graphene oxide: Efficient removal of trihalomethanes from drinking water. SCIENCE OF THE TOTAL ENVIRONMENT, 839 (156228). [PMID:35643141] [10.1016/j.scitotenv.2022.156228]
5. Feilong Dong, Zhen Pang, Jianquan Yu, Jing Deng, Xueyan Li, Xiaoyan Ma, Andrea M. Dietrich, Yang Deng. (2022) Spatio-temporal variability of halogenated disinfection by-products in a large-scale two-source water distribution system with enhanced chlorination. JOURNAL OF HAZARDOUS MATERIALS, 423 (127113). [PMID:34523488] [10.1016/j.jhazmat.2021.127113]
6. Yan Wang, Lingfei Li, Zhe Sun, Huiyu Dong, Jianwei Yu, Zhimin Qiang. (2021) Removal of disinfection by-product precursors in drinking water treatment processes: Is fluorescence parallel factor analysis a promising indicator?. JOURNAL OF HAZARDOUS MATERIALS, 418 (126298). [PMID:34119980] [10.1016/j.jhazmat.2021.126298]
7. Sun Qiangqiang, Wang Dehui, Li Yanan, Zhang Jiahui, Ye Shuji, Cui Jiaxi, Chen Longquan, Wang Zuankai, Butt Hans-Jürgen, Vollmer Doris, Deng Xu. (2019) Surface charge printing for programmed droplet transport. NATURE MATERIALS, 18 (9): (936-941). [PMID:31332340] [10.1038/s41563-019-0440-2]
8. Wu Yang, Lili Dong, Zhen Luo, Xiaochun Cui, Jiancong Liu, Zhongmou Liu, Mingxin Huo. (2014) Application of ultrasound and quartz sand for the removal of disinfection byproducts from drinking water. CHEMOSPHERE, 101 (34). [PMID:24296031] [10.1016/j.chemosphere.2013.11.018]

References

1. . (1991-01-01) Bromoform.. IARC monographs on the evaluation of carcinogenic risks to humans, 52 (213-242). [PMID:1960842]
2. . (1999-09-07) Bromoform.. IARC monographs on the evaluation of carcinogenic risks to humans, 71 Pt 3 (1309-1316). [PMID:10476403]
3. J Caro,A Serrano,M Gallego. (2006-11-10) Sensitive headspace gas chromatography-mass spectrometry determination of trihalomethanes in urine.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 848 ((2)): (277-282). [PMID:17092785]
4. Angelo Viti,Patrizia Tinti,Guia Verrucoli,Chiara Lorini,Cristiana Sacco,Eudes Lanciotti. (2007-01-09) [Contamination by disinfection byproducts (DPBs) and microbiological quality of dialysis water: a study in an Italian hospital dialysis service].. Igiene e sanita pubblica, 62 ((2)): (173-187). [PMID:17206188]
5. Embarka Chaib,Demetrios Moschandreas. (2007-07-31) Modeling daily variation of trihalomethane compounds in drinking water system, Houston, Texas.. Journal of hazardous materials, 151 ((2-3)): (662-668). [PMID:17658688]
6. A B DeAngelo,C P Jones,M P Moyer. (2007-12-14) Development of normal human colon cell cultures to identify priority unregulated disinfection by-products with a carcinogenic potential.. Water science and technology : a journal of the International Association on Water Pollution Research, 56 ((12)): (51-55). [PMID:18075178]
7. Mallika Panyakapo,Sarisak Soontornchai,Pongsri Paopuree. (2008-07-04) Cancer risk assessment from exposure to trihalomethanes in tap water and swimming pool water.. Journal of environmental sciences (China), 20 ((3)): (372-378). [PMID:18595407]
8. Eva Aguilera-Herrador,Rafael Lucena,Soledad Cárdenas,Miguel Valcárcel. (2008-09-27) Determination of trihalomethanes in waters by ionic liquid-based single drop microextraction/gas chromatographic/mass spectrometry.. Journal of chromatography. A, 1209 ((1-2)): (76-82). [PMID:18817919]
9. Kohji Yamamoto,Yoshiaki Mori. (2009-05-29) Simulating distribution of trihalomethane in tap water in the area receiving a combination of advanced treated water and conventionally treated different source water: 1998, 1999 and 2002 data on Osaka Prefecture and its surrounding cities, Japan.. Bulletin of environmental contamination and toxicology, 83 ((5)): (677-680). [PMID:19475326]
10. Kohji Yamamoto,Yoshiaki Mori. (2009-05-29) Episodic trihalomethane species and levels in tap water at a start of operation of advanced treatment in Osaka Prefectural water supplies.. Bulletin of environmental contamination and toxicology, 83 ((5)): (674-676). [PMID:19475327]
11. Luis A Tercero Espinoza,Maximilian Rembor,Clara Arribas Matesanz,Axel Heidt,Fritz H Frimmel. (2009-07-25) Formation of bromoform in irradiated titanium dioxide suspensions with varying photocatalyst, dissolved organic carbon and bromide concentrations.. Water research, 43 ((17)): (4143-4148). [PMID:19628249]
12. Natalia Jakubowska,Bernhard Henkelmann,Karl-Werner Schramm,Jacek Namiesnik. (2009-09-24) Optimization of a novel procedure for determination of VOCs in water and human urine samples based on SBSE coupled with TD-GC-HRMS.. Journal of chromatographic science, 47 ((8)): (689-693). [PMID:19772746]
13. Stacey L Carrier,Thomas J Preston,Maitreya Dutta,Andrew C Crowther,F Fleming Crim. (2009-12-09) Ultrafast observation of isomerization and complexation in the photolysis of bromoform in solution.. The journal of physical chemistry. A, 114 ((3)): (1548-1555). [PMID:19968312]
14. M Valcke,K Krishnan. (2010-10-26) Evaluation of the impact of the exposure route on the human kinetic adjustment factor.. Regulatory toxicology and pharmacology : RTP, 59 ((2)): (258-269). [PMID:20969910]
15. Carolina Lourencetti,Joan O Grimalt,Esther Marco,Pilar Fernandez,Laia Font-Ribera,Cristina M Villanueva,Manolis Kogevinas. (2012-05-11) Trihalomethanes in chlorine and bromine disinfected swimming pools: air-water distributions and human exposure.. Environment international, 45 (59-67). [PMID:22572118]
16. Vesna D Vitnik,Zeljko J Vitnik,Ivan O Juranić. (2012-06-05) Carbenic vs. ionic mechanistic pathway in reaction of cyclohexanone with bromoform.. Journal of molecular modeling, 18 ((10)): (4721-4728). [PMID:22660943]
17. Zelinda Isabel Silva,Maria Helena Rebelo,Manuela Manso Silva,Ana Martins Alves,Maria da Conceição Cabral,Ana Cristina Almeida,Fátima Rôxo Aguiar,Anabela Lopes de Oliveira,Ana Cruz Nogueira,Hermínia Rodrigues Pinhal,Pedro Manuel Aguiar,Ana Sofia Cardoso. (2012-07-14) Trihalomethanes in Lisbon indoor swimming pools: occurrence, determining factors, and health risk classification.. Journal of toxicology and environmental health. Part A, 75 ((13-15)): (878-892). [PMID:22788374]
18. Radovan Spurny,Bert Billen,Rebecca J Howard,Marijke Brams,Sarah Debaveye,Kerry L Price,David A Weston,Sergei V Strelkov,Jan Tytgat,Sonia Bertrand,Daniel Bertrand,Sarah C R Lummis,Chris Ulens. (2013-02-01) Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC).. The Journal of biological chemistry, 288 ((12)): (8355-8364). [PMID:23364792]
19. Fabien Goulay,Adeeb Derakhshan,Eamonn Maher,Adam J Trevitt,John D Savee,Adam M Scheer,David L Osborn,Craig A Taatjes. (2013-02-14) Formation of dimethylketene and methacrolein by reaction of the CH radical with acetone.. Physical chemistry chemical physics : PCCP, 15 ((11)): (4049-4058). [PMID:23403615]
20. Zhen He,Gui-Peng Yang,Xiao-Lan Lu,Hong-Hai Zhang. (2013-03-08) Distributions and sea-to-air fluxes of chloroform, trichloroethylene, tetrachloroethylene, chlorodibromomethane and bromoform in the Yellow Sea and the East China Sea during spring.. Environmental pollution (Barking, Essex : 1987), 177 (28-37). [PMID:23466729]
21. Messaouda Khallef,Recep Liman,Muhsin Konuk,İbrahim Hakkı Ciğerci,Djameleddine Benouareth,Mouna Tabet,Ahlem Abda. (2013-12-24) Genotoxicity of drinking water disinfection by-products (bromoform and chloroform) by using both Allium anaphase-telophase and comet tests.. Cytotechnology, 67 ((2)): (207-213). [PMID:24363168]
22. Elumalai Gopi,Irishi N N Namboothiri. (2014-03-29) Synthesis of α-tribromomethylamines via Mg-mediated addition of bromoform to imines.. Organic & biomolecular chemistry, 12 ((17)): (2769-2777). [PMID:24668340]
23. A Domínguez-Tello,A Arias-Borrego,T García-Barrera,J L Gómez-Ariza. (2015-06-01) Application of hollow fiber liquid phase microextraction for simultaneous determination of regulated and emerging iodinated trihalomethanes in drinking water.. Journal of chromatography. A, 1402 (8-16). [PMID:26026483]
24. Haiting Zhang,Huiyu Dong,Craig Adams,Zhimin Qiang,Gang Luan,Lei Wang. (2015-07-05) Formation and speciation of disinfection byproducts during chlor(am)ination of aquarium seawater.. Journal of environmental sciences (China), 33 (116-124). [PMID:26141884]
25. Maria Jose Cardador,Jose Fernández-Salguero,Mercedes Gallego. (2015-07-19) Simultaneous quantification of trihalomethanes and haloacetic acids in cheese by on-line static headspace gas chromatography-mass spectrometry.. Journal of chromatography. A, 1408 (22-29). [PMID:26187762]
26. R K Padhi,K K Satpathy,S Subramanian. (2015-09-01) Impact of groundwater surface storage on chlorination and disinfection by-product formation.. Journal of water and health, 13 ((3)): (838-847). [PMID:26322769]
27. Doddipatla, et al.. (2021) A chemical dynamics study on the gas phase formation of thioformaldehyde (H2CS) and its thiohydroxycarbene isomer (HCSH).. Proceedings of the National Academy of Sciences of the USA, 117 (22712-22719). [PMID:32859759]
28. Jong-Ryul Park,Eleonore C L Bolle,Amanda Dos Santos Cavalcanti,Annelore Podevyn,Joachim F R Van Guyse,Aurelien Forget,Richard Hoogenboom,Tim R Dargaville. (2021-01-07) Injectable biocompatible poly(2-oxazoline) hydrogels by strain promoted alkyne-azide cycloaddition.. Biointerphases, 16 ((1)): (011001-011001). [PMID:33401918]
29. Tao Zhang,Jonas S Johansson. (2004-12-25) A calorimetric study on the binding of six general anesthetics to the hydrophobic core of a model protein.. Biophysical chemistry, 113 ((2)): (169-174). [PMID:15617824]
30. David R Geter,Tanya M Moore,Michael H George,Steve R Kilburn,James W Allen,Gail M Nelson,Ernest Winkfield,Anthony B DeAngelo. (2005-06-01) Tribromomethane exposure and dietary folate deficiency in the formation of aberrant crypt foci in the colons of F344/N rats.. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 43 ((9)): (1405-1412). [PMID:15921841]
31. Yu-Mei Tan,Kai H Liao,Harvey J Clewell. (2006-11-17) Reverse dosimetry: interpreting trihalomethanes biomonitoring data using physiologically based pharmacokinetic modeling.. Journal of exposure science & environmental epidemiology, 17 ((7)): (591-603). [PMID:17108893]
32. Bichismita Sahu,Guddeangadi N Gururaja,Shaikh M Mobin,Irishi N N Namboothiri. (2009-02-26) Facile synthesis of beta-tribromomethyl and dibromomethylenated nitroalkanes via conjugate addition of bromoform to nitroalkenes.. The Journal of organic chemistry, 74 ((6)): (2601-2604). [PMID:19239256]
33. Szilvia Pothoczki,László Temleitner,Shinji Kohara,Pál Jóvári,László Pusztai. (2011-03-10) The liquid structure of haloforms CHCl3 and CHBr3.. Journal of physics. Condensed matter : an Institute of Physics journal, 22 ((40)): (404211-404211). [PMID:21386572]
34. S K Pal,A S Mereshchenko,E V Butaeva,P Z El-Khoury,A N Tarnovsky. (2013-04-06) Global sampling of the photochemical reaction paths of bromoform by ultrafast deep-UV through near-IR transient absorption and ab initio multiconfigurational calculations.. The Journal of chemical physics, 138 ((12)): (124501-124501). [PMID:23556730]
35. R Rajamohan,Usha Natesan,V P Venugopalan,Puspalata Rajesh,S Rangarajan. (2015-07-23) Removal of trihalomethane from chlorinated seawater using gamma radiation.. Environmental science and pollution research international, 22 ((23)): (18772-18778). [PMID:26199004]
36. Jiaben Zhong, Hangyan Zhang, Yina Cai, Xiuping Chen, Zhiyuan Fang, Dun Deng. (2023) Rapid and visual detection of dichloroacetonitrile in water. ANALYST, 148 (21): (5390-5394). [PMID:37750310] [10.1039/D3AN01282D]
37. Ximiao Zhu, Chenhui Hao, Mengze Zhang, Bingyan Lan. (2023) Enhanced Adsorption of Bromoform onto Microplastic Polyethylene Terephthalate Exposed to Ozonation and Chlorination. MOLECULES, 28 (1): (259). [PMID:36615452] [10.3390/molecules28010259]
38. Yang Guo, Huachao Li, Guofeng Qiu, Yan Li, Yanjie Niu, Jie Xu, Wenke Jia, Yixin Zhang, Jianjun Wu, Fanhui Guo. (2023) Processing of coal gasification fine slag by different physical separation methods: Fate of typical heavy metals and comparison analysis on products. SEPARATION AND PURIFICATION TECHNOLOGY, 306 (122675). [PMID:] [10.1016/j.seppur.2022.122675]
39. Pamphile Ndagijimana, Xuejiao Liu, Qingxin Xu, Zhiwei Li, Beibei Pan, Xu Liao, Yin Wang. (2022) Nanoscale zero-valent iron/silver@activated carbon-reduced graphene oxide: Efficient removal of trihalomethanes from drinking water. SCIENCE OF THE TOTAL ENVIRONMENT, 839 (156228). [PMID:35643141] [10.1016/j.scitotenv.2022.156228]
40. Feilong Dong, Zhen Pang, Jianquan Yu, Jing Deng, Xueyan Li, Xiaoyan Ma, Andrea M. Dietrich, Yang Deng. (2022) Spatio-temporal variability of halogenated disinfection by-products in a large-scale two-source water distribution system with enhanced chlorination. JOURNAL OF HAZARDOUS MATERIALS, 423 (127113). [PMID:34523488] [10.1016/j.jhazmat.2021.127113]
41. Yan Wang, Lingfei Li, Zhe Sun, Huiyu Dong, Jianwei Yu, Zhimin Qiang. (2021) Removal of disinfection by-product precursors in drinking water treatment processes: Is fluorescence parallel factor analysis a promising indicator?. JOURNAL OF HAZARDOUS MATERIALS, 418 (126298). [PMID:34119980] [10.1016/j.jhazmat.2021.126298]
42. Sun Qiangqiang, Wang Dehui, Li Yanan, Zhang Jiahui, Ye Shuji, Cui Jiaxi, Chen Longquan, Wang Zuankai, Butt Hans-Jürgen, Vollmer Doris, Deng Xu. (2019) Surface charge printing for programmed droplet transport. NATURE MATERIALS, 18 (9): (936-941). [PMID:31332340] [10.1038/s41563-019-0440-2]
43. Wu Yang, Lili Dong, Zhen Luo, Xiaochun Cui, Jiancong Liu, Zhongmou Liu, Mingxin Huo. (2014) Application of ultrasound and quartz sand for the removal of disinfection byproducts from drinking water. CHEMOSPHERE, 101 (34). [PMID:24296031] [10.1016/j.chemosphere.2013.11.018]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.