Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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T423462-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $103.90 |
Exhibits antibacterial, antifungal, antiviral, and anti-inflammatory activities.
Synonyms | triclosan | 3380-34-5 | 5-CHLORO-2-(2,4-DICHLOROPHENOXY)PHENOL | Cloxifenolum | Irgasan | 2,4,4'-Trichloro-2'-hydroxydiphenyl ether | Triclosanum | Irgasan DP300 | Stri-Dex Cleansing Bar | CH 3565 | Phenol, 5-chloro-2-(2,4-dichlorophenoxy)- | Lexol 300 | 5-Chloro-2-(2,4-dichloro |
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Specifications & Purity | 10mM in DMSO |
Biochemical and Physiological Mechanisms | Irgasan is a broad spectrum antimicrobial agent. It is an inhibitor of the enoyl-ACP (acyl-carrier protein) reductase component of type II fatty acid synthase (FAS-II) in bacteria and Plasmodium. It also inhibits mammalian fatty acid synthase (FASN), and |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
ALogP | 5 |
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IUPAC Name | 5-chloro-2-(2,4-dichlorophenoxy)phenol |
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INCHI | InChI=1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H |
InChi Key | XEFQLINVKFYRCS-UHFFFAOYSA-N |
Canonical SMILES | C1=CC(=C(C=C1Cl)O)OC2=C(C=C(C=C2)Cl)Cl |
Isomeric SMILES | C1=CC(=C(C=C1Cl)O)OC2=C(C=C(C=C2)Cl)Cl |
WGK Germany | 3 |
RTECS | KO1100000 |
PubChem CID | 5564 |
UN Number | 3077 |
Molecular Weight | 289.54 |
Beilstein | 2057142 |
Reaxy-Rn | 2057142 |
Enter Lot Number to search for COA:
Boil Point(°C) | 290 °C |
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Melt Point(°C) | 54-57.3°C |
Pictogram(s) | GHS09, GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. |
WGK Germany | 3 |
RTECS | KO1100000 |
Reaxy-Rn | 2057142 |
Merck Index | 9657 |
1. Lulu Chen, Xiaona Dong, Ruonan Feng, Wanying Li, Dahu Ding, Tianming Cai, Canlan Jiang. (2023) Oxalic acid enhanced ferrous/persulfate process for the degradation of triclosan in soil: Efficiency, mechanism and a column study. CHEMICAL ENGINEERING JOURNAL, 473 (144961). [PMID:] |
2. Ruonan Feng, Lulu Chen, Wanying Li, Tianming Cai, Canlan Jiang. (2023) Activation of persulfate with natural organic acids (ascorbic acid/catechin hydrate) for naproxen degradation in water and soil: Mechanism, pathway, and toxicity assessment. JOURNAL OF HAZARDOUS MATERIALS, 459 (132152). [PMID:37544179] |
3. Xiao Sihua, Wan Jinquan, Wang Yan, Yan Zhicheng, Ma Yongwen, Sun Jian, Tang Min, Cao Jianye, Chen Jinxin. (2023) Distribution, Sources, and Risk Assessment of Emerging Contaminants in the Effluents from Large-Scale Wastewater Treatment Plants in Guangzhou Central Districts, South China. WATER AIR AND SOIL POLLUTION, 234 (7): (1-17). [PMID:] |
4. Tongchen Zhang, Huan Wu, Matin Naghizadeh, Qian Zheng, Sheying Dong. (2023) Magnetic Porous Polymer with −OH Groups as Sorbent for Excellent Extraction and Removal of Personal Care Products from Water. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 62 (22): (8873–8881). [PMID:] |
5. Ting Lu, Tong Zhang, Weishu Yang, Bin Yang, Jing Cao, Yang Yang, Mei Li. (2023) Molecular Toxicity Mechanism Induced by the Antibacterial Agent Triclosan in Freshwater Euglena gracilis Based on the Transcriptome. Toxics, 11 (5): (414). [PMID:37235229] |
6. Junjing Li, Yu Wang, Bin Zhao, Jing Ding, Jun Zhang, Menghua Yin, Zhaohui Zhang, Shumin Ma, Yaqian Liu, Zilin Tan, Hongwei Zhang, Liang Wang, Dionysios D. Dionysiou. (2023) Unraveling kinetics and mechanism of electrocatalytic hydrodechlorination of chlorinated PPCPs by nickel-cobalt metal organic framework supported palladium composite electrode. APPLIED CATALYSIS B-ENVIRONMENTAL, 332 (122754). [PMID:] |
7. Shizong Wang, Jun Hu, Jianlong Wang. (2023) Simultaneous removal of triclosan and nitrate by a stable denitrifying microbial consortium. Journal of Environmental Chemical Engineering, 11 (109387). [PMID:] |
8. Qu Zhang, Chao Xue, Gary Owens, Zuliang Chen. (2023) Preparation of bionanomaterial based on green reduced graphene immobilized Ochrobactrum sp. FJ1: Optimization, characterization and its application. SEPARATION AND PURIFICATION TECHNOLOGY, 310 (123144). [PMID:] |
9. Shi-Ming Niu, Qian Zhang, Thangavel Sangeetha, Lei Chen, Lan-Ying Liu, Ping Wu, Chao Zhang, Wei-Mon Yan, He Liu, Min-Hua Cui, Ai-Jie Wang. (2023) Evaluation of the effect of biofilm formation on the reductive transformation of triclosan in cathode-modified electrolytic systems. SCIENCE OF THE TOTAL ENVIRONMENT, 865 (161308). [PMID:36596419] |
10. Bingzhi Yu, Wen Yan, Yunjuan Meng, Yinan Zhang, Xizi Li, Yan Li, Yuchi Zhong, Jiafeng Ding, Hangjun Zhang. (2023) Selected dechlorination of triclosan by high-performance g-C3N4/Bi2MoO6 composites: Mechanisms and pathways. CHEMOSPHERE, 312 (137247). [PMID:36414036] |
11. Rijia Jiang, Mengyue Liu, Xiangyu Zheng, Xing Zhou. (2022) Metal-Free, Low-Surface Energy, and Self-Healing Polyurethane Coating with an Excellent Antifouling Property. ACS Applied Polymer Materials, 4 (11): (8594–8603). [PMID:] |
12. Yan Jin, Zou Ying, Zhang Fengrui, Zhang Shenghua, Huang Xinyue, Benoit Gaboury. (2023) Growth, ROS accumulation site, and photosynthesis inhibition mechanism of Chlorella vulgaris by triclosan. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 30 (5): (12125-12137). [PMID:36107294] |
13. Mingjie Huang, Yu-Sheng Li, Chuan-Qi Zhang, Chao Cui, Qing-Qing Huang, Mengkai Li, Zhimin Qiang, Tao Zhou, Xiaohui Wu, Han-Qing Yu. (2022) Facilely tuning the intrinsic catalytic sites of the spinel oxide for peroxymonosulfate activation: From fundamental investigation to pilot-scale demonstration. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119 (30): (e2202682119). [PMID:35858430] |
14. Li Chen, Tahir Maqbool, Wanyi Fu, Yulong Yang, Congyu Hou, Jianning Guo, Xihui Zhang. (2022) Highly efficient manganese (III) oxide submerged catalytic ceramic membrane for nonradical degradation of emerging organic compounds. SEPARATION AND PURIFICATION TECHNOLOGY, 295 (121272). [PMID:] |
15. Qingxin Xu, Xuejiao Liu, Dengguo Lai, Zhenjiao Xing, Pamphile Ndagijimana, Zhiwei Li, Yin Wang. (2022) One-step synthesis of nanoscale zero-valent iron modified hydrophobic mesoporous activated carbon for efficient removal of bulky organic pollutants. Journal of Cleaner Production, 356 (131854). [PMID:] |
16. Xuguang Liu, Fengqin Chang, Dayu Zhang, Meijie Ren. (2022) Influence of nitrate/nitrite on the degradation and transformation of triclosan in the UV based disinfection. CHEMOSPHERE, 298 (134258). [PMID:35271891] |
17. Gaofeng Zhou, Yongsheng Fu, Runyu Zhou, Li Zhang, Linyue Zhang, Jiewen Deng, Yiqing Liu. (2022) Efficient degradation of organic contaminants by magnetic cobalt ferrite combined with peracetic acid. PROCESS SAFETY AND ENVIRONMENTAL PROTECTION, 160 (376). [PMID:] |
1. Lulu Chen, Xiaona Dong, Ruonan Feng, Wanying Li, Dahu Ding, Tianming Cai, Canlan Jiang. (2023) Oxalic acid enhanced ferrous/persulfate process for the degradation of triclosan in soil: Efficiency, mechanism and a column study. CHEMICAL ENGINEERING JOURNAL, 473 (144961). [PMID:] |
2. Ruonan Feng, Lulu Chen, Wanying Li, Tianming Cai, Canlan Jiang. (2023) Activation of persulfate with natural organic acids (ascorbic acid/catechin hydrate) for naproxen degradation in water and soil: Mechanism, pathway, and toxicity assessment. JOURNAL OF HAZARDOUS MATERIALS, 459 (132152). [PMID:37544179] |
3. Xiao Sihua, Wan Jinquan, Wang Yan, Yan Zhicheng, Ma Yongwen, Sun Jian, Tang Min, Cao Jianye, Chen Jinxin. (2023) Distribution, Sources, and Risk Assessment of Emerging Contaminants in the Effluents from Large-Scale Wastewater Treatment Plants in Guangzhou Central Districts, South China. WATER AIR AND SOIL POLLUTION, 234 (7): (1-17). [PMID:] |
4. Tongchen Zhang, Huan Wu, Matin Naghizadeh, Qian Zheng, Sheying Dong. (2023) Magnetic Porous Polymer with −OH Groups as Sorbent for Excellent Extraction and Removal of Personal Care Products from Water. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 62 (22): (8873–8881). [PMID:] |
5. Ting Lu, Tong Zhang, Weishu Yang, Bin Yang, Jing Cao, Yang Yang, Mei Li. (2023) Molecular Toxicity Mechanism Induced by the Antibacterial Agent Triclosan in Freshwater Euglena gracilis Based on the Transcriptome. Toxics, 11 (5): (414). [PMID:37235229] |
6. Junjing Li, Yu Wang, Bin Zhao, Jing Ding, Jun Zhang, Menghua Yin, Zhaohui Zhang, Shumin Ma, Yaqian Liu, Zilin Tan, Hongwei Zhang, Liang Wang, Dionysios D. Dionysiou. (2023) Unraveling kinetics and mechanism of electrocatalytic hydrodechlorination of chlorinated PPCPs by nickel-cobalt metal organic framework supported palladium composite electrode. APPLIED CATALYSIS B-ENVIRONMENTAL, 332 (122754). [PMID:] |
7. Shizong Wang, Jun Hu, Jianlong Wang. (2023) Simultaneous removal of triclosan and nitrate by a stable denitrifying microbial consortium. Journal of Environmental Chemical Engineering, 11 (109387). [PMID:] |
8. Qu Zhang, Chao Xue, Gary Owens, Zuliang Chen. (2023) Preparation of bionanomaterial based on green reduced graphene immobilized Ochrobactrum sp. FJ1: Optimization, characterization and its application. SEPARATION AND PURIFICATION TECHNOLOGY, 310 (123144). [PMID:] |
9. Shi-Ming Niu, Qian Zhang, Thangavel Sangeetha, Lei Chen, Lan-Ying Liu, Ping Wu, Chao Zhang, Wei-Mon Yan, He Liu, Min-Hua Cui, Ai-Jie Wang. (2023) Evaluation of the effect of biofilm formation on the reductive transformation of triclosan in cathode-modified electrolytic systems. SCIENCE OF THE TOTAL ENVIRONMENT, 865 (161308). [PMID:36596419] |
10. Bingzhi Yu, Wen Yan, Yunjuan Meng, Yinan Zhang, Xizi Li, Yan Li, Yuchi Zhong, Jiafeng Ding, Hangjun Zhang. (2023) Selected dechlorination of triclosan by high-performance g-C3N4/Bi2MoO6 composites: Mechanisms and pathways. CHEMOSPHERE, 312 (137247). [PMID:36414036] |
11. Rijia Jiang, Mengyue Liu, Xiangyu Zheng, Xing Zhou. (2022) Metal-Free, Low-Surface Energy, and Self-Healing Polyurethane Coating with an Excellent Antifouling Property. ACS Applied Polymer Materials, 4 (11): (8594–8603). [PMID:] |
12. Yan Jin, Zou Ying, Zhang Fengrui, Zhang Shenghua, Huang Xinyue, Benoit Gaboury. (2023) Growth, ROS accumulation site, and photosynthesis inhibition mechanism of Chlorella vulgaris by triclosan. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 30 (5): (12125-12137). [PMID:36107294] |
13. Mingjie Huang, Yu-Sheng Li, Chuan-Qi Zhang, Chao Cui, Qing-Qing Huang, Mengkai Li, Zhimin Qiang, Tao Zhou, Xiaohui Wu, Han-Qing Yu. (2022) Facilely tuning the intrinsic catalytic sites of the spinel oxide for peroxymonosulfate activation: From fundamental investigation to pilot-scale demonstration. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119 (30): (e2202682119). [PMID:35858430] |
14. Li Chen, Tahir Maqbool, Wanyi Fu, Yulong Yang, Congyu Hou, Jianning Guo, Xihui Zhang. (2022) Highly efficient manganese (III) oxide submerged catalytic ceramic membrane for nonradical degradation of emerging organic compounds. SEPARATION AND PURIFICATION TECHNOLOGY, 295 (121272). [PMID:] |
15. Qingxin Xu, Xuejiao Liu, Dengguo Lai, Zhenjiao Xing, Pamphile Ndagijimana, Zhiwei Li, Yin Wang. (2022) One-step synthesis of nanoscale zero-valent iron modified hydrophobic mesoporous activated carbon for efficient removal of bulky organic pollutants. Journal of Cleaner Production, 356 (131854). [PMID:] |
16. Xuguang Liu, Fengqin Chang, Dayu Zhang, Meijie Ren. (2022) Influence of nitrate/nitrite on the degradation and transformation of triclosan in the UV based disinfection. CHEMOSPHERE, 298 (134258). [PMID:35271891] |
17. Gaofeng Zhou, Yongsheng Fu, Runyu Zhou, Li Zhang, Linyue Zhang, Jiewen Deng, Yiqing Liu. (2022) Efficient degradation of organic contaminants by magnetic cobalt ferrite combined with peracetic acid. PROCESS SAFETY AND ENVIRONMENTAL PROTECTION, 160 (376). [PMID:] |