Trilostane - 98%, high purity , 3-beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II inhibitor, CAS No.13647-35-3, 3-beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II inhibitor

Item Number

T302496

• Synonyms: AB01274788_02 | Androstane-2-carbonitrile, 4,5-epoxy-17-hydroxy-3-oxo-, (2-alpha,4-alpha,5-alpha,17-beta)- | DTXCID103706 | UNII-L0FPV48Q5R | Vetoryl | (4Alpha,5alpha,17beta)-4,5-epoxy-3,17-dihydroxyandrost-2-ene-2-carbonitrile | BDBM50247882 | Tox21_1124
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: 3 β-hydroxysteroid dehydrogenase inhibitor. Enables the biosynthesis of hormonal steroids in vivo. Orally active.
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: 3-beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II inhibitor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Application：

Trilostane is a synthetic derivative of androstane with adrenocortical suppressive properties. Trilostane reversibly inhibits 3 beta-hydroxysteroid dehydrogenase delta 5-4 isomerase in the adrenal cortex.

Trilostane (Win 24540) is a competitive and orally active 3-β-hydroxysteroiddehydrogenase (3β-HSD) inhibitor. Trilostane is a synthetic nonhormonal steroid. Trilostane can be used for the research of breast cancer and prostate cancer.