Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | TRIPHENYLPHOSPHINE [INCI] | Triphenylphosphine, flakes | CCRIS 4889 | Triphenylphosphine, powder | Tox21_202114 | tripbenylphosphine | AT26025 | EC 210-036-0 | HSDB 4266 | NCGC00257211-01 | triphenyiphosphine | PP 360 | NCGC00091416-01 | triphenyl phosphi |
|---|---|
| Specifications & Purity | ≥95% |
| Storage Temp | Argon charged |
| Shipped In | Normal |
| Product Description | Rhodium and triphenylphosphine catalyst system has been used for the hydroformylation of soybean, safflower and linseed oils and their methyl esters. Polymer supported triphenylphosphine has been reported to efficiently catalyze the γ-addition of pronucleophiles to alkynoate. Triphenylphosphine reacts with hydrated ruthenium trichloride in methanol to afford [RuCl2(PPh3)4], [RuCl2(PPh3)3] and [RuCl3(PPh3)2CH3OH].It participates in the Heck reaction of 4-bromoanisole and ethyl acrylate in ionic liquids. |
Associated Targets(Human)
CYP3A4 Tclin Cytochrome P450 3A4 (0 Activities)
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
CXCL8 Tchem Interleukin-8 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
KCNH2 Tclin HERG (29587 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CXCL8 Tchem Interleukin-8 (642 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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CCRF-CEM (65223 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Lymphoblastoid cell (5959 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| IUPAC Name | triphenylphosphane |
|---|---|
| INCHI | InChI=1S/C18H15P/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H |
| InChi Key | RIOQSEWOXXDEQQ-UHFFFAOYSA-N |
| Canonical SMILES | C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=CC=CC=C3 |
| Isomeric SMILES | C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=CC=CC=C3 |
| WGK Germany | 2 |
| RTECS | SZ3500000 |
| PubChem CID | 11776 |
| UN Number | 3077 |
| Packing Group | III |
| Molecular Weight | 262.29 |
| Beilstein | 610776 |
| Reaxy-Rn | 610776 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 B2315544 | Certificate of Analysis | Aug 29, 2024 | T104478 |
| B2313665 | Certificate of Analysis | Feb 21, 2023 | T104478 |
| B2313649 | Certificate of Analysis | Feb 21, 2023 | T104478 |
| B2315399 | Certificate of Analysis | Feb 20, 2023 | T104478 |
| I2220613 | Certificate of Analysis | Sep 27, 2022 | T104478 |
| I2220614 | Certificate of Analysis | Sep 27, 2022 | T104478 |
| G2215755 | Certificate of Analysis | Jul 20, 2022 | T104478 |
| E2205067 | Certificate of Analysis | May 06, 2022 | T104478 |
| E2205068 | Certificate of Analysis | May 06, 2022 | T104478 |
| C2112143 | Certificate of Analysis | May 13, 2021 | T104478 |
| G2215751 | Certificate of Analysis | May 13, 2021 | T104478 |
Show more⌵
Chemical and Physical Properties
| Solubility | Soluble in ether, acetone, chloroform (50 mg/ml), and alcohol. Insoluble in water. |
|---|---|
| Sensitivity | Light sensitive. |
| Flash Point(°F) | 356 °F |
| Flash Point(°C) | (open cup)180℃ |
| Boil Point(°C) | 377°C |
| Melt Point(°C) | 80.5°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS08, GHS07 |
|---|---|
| Signal | Danger |
| Hazard Statements | H412:Harmful to aquatic life with long lasting effects H302:Harmful if swallowed H317:May cause an allergic skin reaction H350:May cause cancer |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. |
| WGK Germany | 2 |
| RTECS | SZ3500000 |
| Reaxy-Rn | 610776 |
| Class | 9 |
| Merck Index | 9743 |
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Citations of This Product
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| 2. Bing-Feng Zhang,Lei Xing,Peng-Fei Cui,Feng-Zhen Wang,Rong-Lin Xie,Jia-Liang Zhang,Mei Zhang,Yu-Jing He,Jin-Yuan Lyu,Jian-Bin Qiao,Bao-An Chen,Hu-Lin Jiang. (2015-05-26) Mitochondria apoptosis pathway synergistically activated by hierarchical targeted nanoparticles co-delivering siRNA and lonidamine.. Biomaterials, 61 (178-189). [PMID:26004233] |
| 3. Xiangbin Sun, Peng Cao, Xue Bai, Yufeng He, Pengfei Song, Rongmin Wang. (2023) Poly(phosphonium)-Functionalized Double-Armed β-CD Antimicrobial Material via RAFT. MACROMOLECULES, 56 (23): (9498–9508). [PMID:16239144] [10.1021/acs.macromol.3c01885] |
| 4. Qian Zhang, Ying Li, Shuai Wang, Donghao Gu, Cuihua Zhang, Shihao Xu, Xiaoli Fang, Chenyang Li, Haiqiang Wu, Wei Xiong. (2024) Chitosan-based oral nanoparticles as an efficient platform for kidney-targeted drug delivery in the treatment of renal fibrosis. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 256 (128315). [PMID:38000609] [10.1016/j.ijbiomac.2023.128315] |
| 5. Yanan Wang, Huichao Wei, Keyang Li, Liru Liu, Yingfei Zhu, Xinyuan Wang, Jiahui Yan, Liangmin Yu, Xuefeng Yan, Zhiyu He. (2024) Ros-responsive dextran-phenylboronic acid-silibinin nanoparticles for targeting delivery of BAPTA-AM to effectively eliminate calcium overload-mediated inflammatory cascades and mitochondrial apoptosis: Alleviating acute liver injury. CHEMICAL ENGINEERING JOURNAL, 480 (148283). [PMID:] [10.1016/j.cej.2023.148283] |
| 6. Yunping Yao, Tianliang Wang, Zhiyuan Qiang, Wenqi Du, Changmo Li. (2024) Mechanisms of the Formation of Nonvolatile and Volatile Oxidation Products from Methyl Linoleic Acid at High Temperatures. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 72 (1): (704–714). [PMID:38131267] [10.1021/acs.jafc.3c04405] |
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