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Tris(hydroxymethyl)aminomethane - ACS, ≥99.8%, high purity , CAS No.77-86-1

  • ACS
  • ≥99.8%
Item Number
T110600
Grouped product items
SKUSizeAvailabilityPrice Qty
T110600-25g
25g
Available within 1-2 weeks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$13.90
T110600-100g
100g
In stock
$22.90
T110600-500g
500g
In stock
$149.90
T110600-12×500g
12×500g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,499.90

Basic Description

SynonymsTrometamol|TROMETHAMINE|77-86-1|Tris(Hydroxymethyl)aminomethane|Tris|2-Amino-2-(hydroxymethyl)propane-1,3-diol|Tham|Trisamine|Trizma|Tris base|2-Amino-2-(hydroxymethyl)-1,3-propanediol|Tris buffer|Tromethane|Tris-base|Trisaminol|Pehanorm|Talatrol|Trisamin
Specifications & PurityACS, ≥99.8%
Shipped InNormal
GradeACS

Associated Targets

CTH Tchem Cystathionine gamma-lyase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP1A2 Tchem Cytochrome P450 1A2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CNR1 Tclin Cannabinoid receptor 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DRD2 Tclin D(2) dopamine receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DRD4 Tchem D(4) dopamine receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ERBB2 Tclin Receptor tyrosine-protein kinase erbB-2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ELANE Tclin Neutrophil elastase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

EGFR Tclin Epidermal growth factor receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AVPR1A Tclin Vasopressin V1a receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HMGCR Tclin 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HRH1 Tclin Histamine H1 receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC6A3 Tclin Sodium-dependent dopamine transporter 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC6A4 Tclin Sodium-dependent serotonin transporter 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SIGMAR1 Tclin Sigma non-opioid intracellular receptor 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CA2 Tclin Carbonic anhydrase 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DRD3 Tclin D(3) dopamine receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

FLT1 Tclin Vascular endothelial growth factor receptor 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRM3 Tclin Muscarinic acetylcholine receptor M3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRM4 Tclin Muscarinic acetylcholine receptor M4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA2B Tclin Alpha-2B adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA2C Tclin Alpha-2C adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR2A Tclin 5-hydroxytryptamine receptor 2A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADORA2A Tclin Adenosine receptor A2a 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ACHE Tclin Acetylcholinesterase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA1B Tclin Alpha-1B adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA2A Tclin Alpha-2A adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRB1 Tclin Beta-1 adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA1A Tclin Alpha-1A adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AR Tclin Androgen receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AKR1B1 Tclin Aldose reductase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADORA1 Tclin Adenosine receptor A1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR1A Tclin 5-hydroxytryptamine receptor 1A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADORA3 Tchem Adenosine receptor A3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR6 Tchem 5-hydroxytryptamine receptor 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HTR2B Tclin 5-hydroxytryptamine receptor 2B 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

EDNRA Tclin Endothelin-1 receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

OPRD1 Tclin Delta-type opioid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

OPRK1 Tclin Kappa-type opioid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

OPRM1 Tclin Mu-type opioid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NOS2 Tchem Nitric oxide synthase, inducible 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TACR1 Tclin Substance-P receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NOS1 Tchem Nitric oxide synthase, brain 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 2-amino-2-(hydroxymethyl)propane-1,3-diol
INCHI InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
InChi Key LENZDBCJOHFCAS-UHFFFAOYSA-N
Canonical SMILES C(C(CO)(CO)N)O
Isomeric SMILES C(C(CO)(CO)N)O
WGK Germany 2
RTECS TY2900000
PubChem CID 6503
Molecular Weight 121.14
Beilstein 741883

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

47 results found

Lot NumberCertificate TypeDateItem
F2412385Certificate of AnalysisJun 15, 2024 T110600
F2412381Certificate of AnalysisJun 15, 2024 T110600
F2412379Certificate of AnalysisJun 15, 2024 T110600
E2424091Certificate of AnalysisMay 27, 2024 T110600
E2424092Certificate of AnalysisMay 27, 2024 T110600
E2424093Certificate of AnalysisMay 27, 2024 T110600
C2428103Certificate of AnalysisApr 11, 2024 T110600
C2428102Certificate of AnalysisApr 11, 2024 T110600
C2428101Certificate of AnalysisApr 11, 2024 T110600
B2421323Certificate of AnalysisFeb 23, 2024 T110600
B2421324Certificate of AnalysisFeb 23, 2024 T110600
B2421315Certificate of AnalysisFeb 23, 2024 T110600
B2421314Certificate of AnalysisFeb 23, 2024 T110600
A2303337Certificate of AnalysisJan 20, 2024 T110600
A2403339Certificate of AnalysisJan 20, 2024 T110600
A2403337Certificate of AnalysisJan 20, 2024 T110600
A2403336Certificate of AnalysisJan 20, 2024 T110600
L2319101Certificate of AnalysisDec 27, 2023 T110600
K2307113Certificate of AnalysisNov 17, 2023 T110600
K2307119Certificate of AnalysisNov 17, 2023 T110600
L1925015Certificate of AnalysisOct 23, 2023 T110600
I2314052Certificate of AnalysisSep 18, 2023 T110600
H2321721Certificate of AnalysisSep 02, 2023 T110600
G2327320Certificate of AnalysisAug 11, 2023 T110600
G2327307Certificate of AnalysisAug 11, 2023 T110600
G2324186Certificate of AnalysisAug 02, 2023 T110600
E2329872Certificate of AnalysisMay 17, 2023 T110600
E23081181Certificate of AnalysisMay 17, 2023 T110600
L2228065Certificate of AnalysisDec 30, 2022 T110600
L2228067Certificate of AnalysisDec 30, 2022 T110600
L2228068Certificate of AnalysisDec 30, 2022 T110600
L2228076Certificate of AnalysisDec 30, 2022 T110600
J2227701Certificate of AnalysisOct 31, 2022 T110600
J2227714Certificate of AnalysisOct 29, 2022 T110600
J2227705Certificate of AnalysisOct 29, 2022 T110600
H2206058Certificate of AnalysisAug 12, 2022 T110600
H2206057Certificate of AnalysisAug 11, 2022 T110600
H2206056Certificate of AnalysisAug 11, 2022 T110600
H2206059Certificate of AnalysisApr 01, 2022 T110600
C2224302Certificate of AnalysisApr 01, 2022 T110600
F2206401Certificate of AnalysisApr 01, 2022 T110600
F2206398Certificate of AnalysisApr 01, 2022 T110600
C2224305Certificate of AnalysisApr 01, 2022 T110600
B2218558Certificate of AnalysisFeb 22, 2022 T110600
F2206400Certificate of AnalysisFeb 22, 2022 T110600
B2218559Certificate of AnalysisFeb 22, 2022 T110600
B2218547Certificate of AnalysisFeb 22, 2022 T110600

more

Chemical and Physical Properties

SensitivityMoisture sensitive.
Boil Point(°C)219-220 °C/10 mmHg (lit.)
Melt Point(°C)167-172 °C (lit.)

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 2
RTECS TY2900000

Related Documents

References

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Solution Calculators