Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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T136386-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $10.90 | |
T136386-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $88.90 |
Synonyms | EX-A4115A | (+)-Prostaglandin F2a | PGF2alpha | PGF-2alpha | PGF2-alpha | PGF2-alpha racemic mixt. | prostaglandin F2alpha | Prostaglandin F2-alpha | (5Z,9alpha,11alpha,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oic acid | DINOPROST [INN] | Dinoprosta |
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Specifications & Purity | Moligand™, ≥95% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of DP 1 receptor;Agonist of DP 2 receptor;Agonist of EP 1 receptor;Agonist of EP 2 receptor;Agonist of EP 3 receptor;Agonist of EP 4 receptor;Agonist of FP receptor;Agonist of TP receptor |
Product Description |
Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour.
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IUPAC Name | (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid |
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INCHI | InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1 |
InChi Key | PXGPLTODNUVGFL-YNNPMVKQSA-N |
Canonical SMILES | CCCCCC(C=CC1C(CC(C1CC=CCCCC(=O)O)O)O)O |
Isomeric SMILES | CCCCC[C@@H](/C=C/[C@H]1[C@@H](C[C@@H]([C@@H]1C/C=C\CCCC(=O)O)O)O)O |
PubChem CID | 5280363 |
Molecular Weight | 354.49 |
PubChem CID | 5280363 |
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ChEBI | CHEBI:15553 |
Wikipedia | Prostaglandin_F2alpha |
ChEMBL Ligand | CHEMBL815 |
CAS Registry No. | 551-11-1 |
DrugCentral Ligand | 912 |
GPCRdb Ligand | PGF2α |
Enter Lot Number to search for COA:
Pictogram(s) | GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H319:Causes serious eye irritation H302:Harmful if swallowed H372:Causes damage to organs through prolonged or repeated exposure H360:May damage fertility or the unborn child H370:Causes damage to organs |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P308+P316:IF exposed or concerned: Get emergency medical help immediately. P319:Get medical help if you feel unwell. |
1. Haonan Xu, Ye Liu, Lu Jin, Xu Chen, Xinghao Chen, Qiao Wang, Zhan Tang. (2023) Preparation and Characterization of Ion-Sensitive Brimonidine Tartrate In Situ Gel for Ocular Delivery. Pharmaceuticals, 16 (1): (90). [PMID:36678587] [10.3390/ph16010090] |
2. Zhipeng Liao, Minh Nhat Nguyen, Gaojie Wan, Jia Xie, Linhan Ni, Junwen Qi, Jiansheng Li, Andrea Iris Schäfer. (2020) Low pressure operated ultrafiltration membrane with integration of hollow mesoporous carbon nanospheres for effective removal of micropollutants. JOURNAL OF HAZARDOUS MATERIALS, 397 (122779). [PMID:32387831] [10.1016/j.jhazmat.2020.122779] |
1. Coulthard G, Erb W, Aggarwal VK. (2012) Stereocontrolled organocatalytic synthesis of prostaglandin PGF2α in seven steps.. Nature, 489 (7415): (278-81). [PMID:22895192] [10.1021/op500134e] |
2. Haonan Xu, Ye Liu, Lu Jin, Xu Chen, Xinghao Chen, Qiao Wang, Zhan Tang. (2023) Preparation and Characterization of Ion-Sensitive Brimonidine Tartrate In Situ Gel for Ocular Delivery. Pharmaceuticals, 16 (1): (90). [PMID:36678587] [10.3390/ph16010090] |
3. Zhipeng Liao, Minh Nhat Nguyen, Gaojie Wan, Jia Xie, Linhan Ni, Junwen Qi, Jiansheng Li, Andrea Iris Schäfer. (2020) Low pressure operated ultrafiltration membrane with integration of hollow mesoporous carbon nanospheres for effective removal of micropollutants. JOURNAL OF HAZARDOUS MATERIALS, 397 (122779). [PMID:32387831] [10.1016/j.jhazmat.2020.122779] |