Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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T614564-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $670.90 | |
T614564-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,000.90 |
Specifications & Purity | Moligand™ |
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Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of indoleamine 2;3-dioxygenase 1;Inhibitor of indoleamine 2;3-dioxygenase 2 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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INCHI | InChI=1S/C15H7N3O4/c19-13-10-7-8(18(21)22)5-6-12(10)17-14(13)16-11-4-2-1-3-9(11)15(17)20/h1-7H |
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InChi Key | UFMQJYHLIUACCG-UHFFFAOYSA-N |
Canonical SMILES | [O-][N+](=O)c1ccc2c(c1)C(=O)c1n2c(=O)c2c(n1)cccc2 |
Isomeric SMILES | C1=CC=C2C(=C1)C(=O)N3C4=C(C=C(C=C4)[N+](=O)[O-])C(=O)C3=N2 |
PubChem CID | 478573 |
PubChem CID | 478573 |
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ChEMBL Ligand | CHEMBL432537 |
Enter Lot Number to search for COA:
1. Yang S, Li X, Hu F, Li Y, Yang Y, Yan J, Kuang C, Yang Q. (2013) Discovery of tryptanthrin derivatives as potent inhibitors of indoleamine 2,3-dioxygenase with therapeutic activity in Lewis lung cancer (LLC) tumor-bearing mice.. J Med Chem, 56 (21): (8321-31). [PMID:24099220] [10.1021/op500134e] |
2. Li J, Li Y, Yang D, Hu N, Guo Z, Kuang C, Yang Q. (2016) Establishment of a human indoleamine 2, 3-dioxygenase 2 (hIDO2) bioassay system and discovery of tryptanthrin derivatives as potent hIDO2 inhibitors.. Eur J Med Chem, 123 (13): (171-179). [PMID:27475108] [10.1021/op500134e] |