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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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T412833-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $70.90 | |
T412833-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $121.90 | |
T412833-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $392.90 | |
T412833-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $587.90 | |
T412833-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $835.90 |
Specifications & Purity | Moligand™, ≥98% |
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Biochemical and Physiological Mechanisms | TTK21 is a CBP/p300 histone acetyltransferase activator. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ACTIVATOR |
Mechanism of action | Activator of CREB binding protein;Activator of E1A binding protein p300 |
Product Description | Information TTK21 is a CBP/p300 histone acetyltransferase activator. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | N-[4-chloro-3-(trifluoromethyl)phenyl]-2-propoxybenzamide |
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INCHI | InChI=1S/C17H15ClF3NO2/c1-2-9-24-15-6-4-3-5-12(15)16(23)22-11-7-8-14(18)13(10-11)17(19,20)21/h3-8,10H,2,9H2,1H3,(H,22,23) |
InChi Key | AQJBXYBDNZHZRE-UHFFFAOYSA-N |
Canonical SMILES | CCCOC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)Cl)C(F)(F)F |
Isomeric SMILES | CCCOC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)Cl)C(F)(F)F |
PubChem CID | 68453302 |
Molecular Weight | 357.75 |
PubChem CID | 68453302 |
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CAS Registry No. | 709676-56-2 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
L2319042 | Certificate of Analysis | Dec 04, 2023 | T412833 |
L2319047 | Certificate of Analysis | Dec 04, 2023 | T412833 |
L2319048 | Certificate of Analysis | Dec 04, 2023 | T412833 |
L2319053 | Certificate of Analysis | Dec 04, 2023 | T412833 |
L2319056 | Certificate of Analysis | Dec 04, 2023 | T412833 |
L2319057 | Certificate of Analysis | Dec 04, 2023 | T412833 |
1. Chatterjee S, Mizar P, Cassel R, Neidl R, Selvi BR, Mohankrishna DV, Vedamurthy BM, Schneider A, Bousiges O, Mathis C et al.. (2013) A novel activator of CBP/p300 acetyltransferases promotes neurogenesis and extends memory duration in adult mice.. J Neurosci, 33 (26): (10698-712). [PMID:23804093] |
2. Singh AK, Neo SH, Liwang C, Pang KKL, Leng JCK, Sinha SH, Shetty MS, Vasudevan M, Rao VJ, Joshi I et al.. (2022) Glucose derived carbon nanosphere (CSP) conjugated TTK21, an activator of the histone acetyltransferases CBP/p300, ameliorates amyloid-beta 1-42 induced deficits in plasticity and associativity in hippocampal CA1 pyramidal neurons.. Aging Cell, 21 (9): (e13675). [PMID:35962576] |
3. Müller F, De Virgiliis F, Kong G, Zhou L, Serger E, Chadwick J, Sanchez-Vassopoulos A, Singh AK, Eswaramoorthy M, Kundu TK et al.. (2022) CBP/p300 activation promotes axon growth, sprouting, and synaptic plasticity in chronic experimental spinal cord injury with severe disability.. PLoS Biol, 20 (9): (e3001310). [PMID:36126035] |
4. Chatterjee S, Cassel R, Schneider-Anthony A, Merienne K, Cosquer B, Tzeplaeff L, Halder Sinha S, Kumar M, Chaturbedy P, Eswaramoorthy M et al.. (2018) Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator.. EMBO Mol Med, 10 (11): (e8587). [PMID:30275019] |