Tyrphostin 23 - ≥98%, high purity , CAS No.118409-57-7

Item Number

T129445

• Synonyms: AG18;Tyrphostin 23; RG-50810 | MLS002153315 | NCGC00016043-03 | AG 18 (Tyrphostin 23) | HMS3414G15 | SMR001230729 | Tocris-0493 | BRD-K49657628-001-02-3 | SR-01000075506-3 | DTXSID9045215 | Lopac-T-7165 | NCGC00016043-06 | SR-01000075506-6 | 3,4-(Dihydrox
• Specifications & Purity: ≥98%
• Biochemical and Physiological Mechanisms: Tyrphostin A23, also known as tyrphostin-23, belongs to a novel class of low molecular weight proteins that inhibit protein tyrosine kinase and block the EGF-dependent autophosphorylation of the receptor. The inhibitors can bind to the EGF receptor kinase
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

AG-18 inhibits EGFR with IC50 of 35 μM.
Tyrphostin 23 can be used as a tyrosine kinase inhibitor for studying rat ghrelin-induced MAPK stimulation in GH3 cells. Tyrphostin 23 has also been used to analyze its effects on secretoneurin (SN)-induced chemotaxis of neutrophils。