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Tyrphostin AG 1433 - ≥95%, high purity , CAS No.168836-03-1
an inhibitor of PDGFR-β, Flk-1, and angiogenesis
Basic Description Synonyms Tyrphostin AG1433 | Tyrphostin AG 1433 | 168835-90-3 | ag1433 | 168836-03-1 | 4-(6,7-dimethylquinoxalin-2-yl)benzene-1,2-diol | 2-(3,4-dihydroxyphenyl)-6,7-dimethylquinoxaline | Tyrphostin AG1433 (hydrochloride) | SU1433 (hydrochloride); AG1433 (hydrochloride) | CHEMBL4203 Specifications & Purity ≥95% Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description Tyrphostin AG 1433 is a specific and potent inhibitor of PDGFR-β (IC|50|= 5.0 μM) and of Flk-1 (IC|50|= 9.3 μM). Tyrphostin AG 1433 also acts as an angiogenesis inhibitor.
Product Properties pKa pKₐ: 8.32 (Predicted), pKₐ: 0.86 (Predicted)
Associated Targets(Human) Names and Identifiers IUPAC Name 4-(6,7-dimethylquinoxalin-2-yl)benzene-1,2-diol INCHI InChI=1S/C16H14N2O2/c1-9-5-12-13(6-10(9)2)18-14(8-17-12)11-3-4-15(19)16(20)7-11/h3-8,19-20H,1-2H3 InChi Key SMKFYHOKXJUJOT-UHFFFAOYSA-N Canonical SMILES CC1=CC2=NC=C(N=C2C=C1C)C3=CC(=C(C=C3)O)O Isomeric SMILES CC1=CC2=NC=C(N=C2C=C1C)C3=CC(=C(C=C3)O)O WGK Germany 1 PubChem CID 2050 Molecular Weight 266.29
Chemical and Physical Properties Solubility Soluble in DMSO. Further dilute with aqueous buffers just before use. Use fresh solutions. Refractive Index n20D1.69 (Predicted) Boil Point(°C) 490.94° C at 760 mmHg (Predicted) Melt Point(°C) 193.62° C (Predicted)
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