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UCM-14216 , CAS No.U614623, Antagonist of LPA 2 receptor

PubChem CID: 164946717

Item Number

U614623

Grouped product items
SKU	Size	Availability	Price	Qty
U614623-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$560.90
U614623-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,500.90

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LPA2 receptor Antagonist

Synonyms

compound 54;GLXC-26113;UCM14216

Specifications & Purity

Moligand™

Grade

Moligand™

Action Type

ANTAGONIST

Mechanism of action

Antagonist of LPA 2 receptor

Associated Targets(Human)

LPAR2 Tchem Lysophosphatidic acid receptor 2 (0 Activities)

Discover Target: LPAR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LPAR1 Tchem Lysophosphatidic acid receptor Edg-2 (779 Activities)

Discover Target: LPAR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LPAR2 Tchem Lysophosphatidic acid receptor Edg-4 (418 Activities)

Discover Target: LPAR2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LPAR3 Tchem Lysophosphatidic acid receptor Edg-7 (471 Activities)

Discover Target: LPAR3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	2-[4-(2,4-dichlorophenoxy)-5-methyl-1H-pyrazol-3-yl]-5-(2H-tetrazol-5-ylmethoxy)phenol
INCHI	InChI=1S/C18H14Cl2N6O3/c1-9-18(29-15-5-2-10(19)6-13(15)20)17(24-21-9)12-4-3-11(7-14(12)27)28-8-16-22-25-26-23-16/h2-7,27H,8H2,1H3,(H,21,24)(H,22,23,25,26)
InChi Key	RZGVUGDKIXTIMM-UHFFFAOYSA-N
Canonical SMILES	ClC1=C(OC=2C(=NNC2C)C3=C(C=C(C=C3)OCC4=NN=NN4)O)C=CC(=C1)Cl
Isomeric SMILES	CC1=C(C(=NN1)C2=C(C=C(C=C2)OCC3=NNN=N3)O)OC4=C(C=C(C=C4)Cl)Cl
PubChem CID	164946717

References

1. Khiar-Fernández N, Zian D, Vázquez-Villa H, Martínez RF, Escobar-Peña A, Foronda-Sainz R, Ray M, Puigdomenech-Poch M, Cincilla G, Sánchez-Martínez M et al.. (2022) Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA₂), UCM-14216, Ameliorates Spinal Cord Injury in Mice.. J Med Chem, 65 (16): (10956-10974). [PMID:35948083] [10.1021/op500134e]

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UCM-14216 , CAS No.U614623, Antagonist of LPA 2 receptor

Basic Description

Associated Targets(Human)

Mechanisms of Action

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Related Documents

References

Solution Calculators

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