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UCM 608 - ≥98%(HPLC), high purity , CAS No.151889-03-1
Basic Description Synonyms UCM608;UCM-608 | CHEBI:107661 | Q27185983 | UCM 608 | N-[2-(5-METHOXY-2-PHENYLINDOL-3-YL)ETHYL]ACETAMIDE | AM20030035 | PDSP2_001778 | SR-01000597657 | NCGC00024727-02 | HMS3675O18 | PDSP1_001796 | HY-101074 | Tocris-0680 | BRD-K41869275-001-01-0 | Melato Specifications & Purity ≥98%(HPLC) Biochemical and Physiological Mechanisms Highly potent melatonin agonist; displays higher affinity and greater potency than melatonin itself. The EC50values for G protein activation in MT1and MT2-transfected cells are 65 and 58 pM respectively. Storage Temp Store at -20°C,Desiccated Shipped In Ice chest + Ice pads Product Description Product Describtion:
UCM 608 is a high affinity melatonin (MT) membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4.
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers Pubchem Sid 488194651 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488194651 IUPAC Name N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide INCHI InChI=1S/C19H20N2O2/c1-13(22)20-11-10-16-17-12-15(23-2)8-9-18(17)21-19(16)14-6-4-3-5-7-14/h3-9,12,21H,10-11H2,1-2H3,(H,20,22) InChi Key OFCLARYYBGKCHN-UHFFFAOYSA-N Canonical SMILES CC(=O)NCCC1=C(NC2=C1C=C(C=C2)OC)C3=CC=CC=C3 Isomeric SMILES CC(=O)NCCC1=C(NC2=C1C=C(C=C2)OC)C3=CC=CC=C3 PubChem CID 4018512 Molecular Weight 308.38
Chemical and Physical Properties Solubility Solvent:ethanol, Max Conc. mg/mL: 30.84, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 30.84, Max Conc. mM: 100
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D2311688