UDP , CAS No.58-98-0, Agonist of GPR17;Activator of K ir6.1;Agonist of P2Y 14 receptor;Agonist of P2Y 6 receptor

Item Number
U614634
Grouped product items
SKUSizeAvailabilityPrice Qty
U614634-25μg
25μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$560.90
U614634-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,500.90

Basic Description

SynonymsUridine 5'-diphosphate | URIDINE DIPHOSPHATE | 58-98-0 | uridine-5'-diphosphate | Uridine 5'-(trihydrogen diphosphate) | UDP | 5'-UDP | Uridine 5'-pyrophosphate | Uridine 5'-pyrophosphoric acid | CHEMBL130266 | [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2
Specifications & PurityMoligand™
GradeMoligand™
Action TypeACTIVATOR, AGONIST
Mechanism of actionAgonist of GPR17;Activator of K ir6.1;Agonist of P2Y 14 receptor;Agonist of P2Y 6 receptor

Associated Targets(Human)

GPR17 Tchem Uracil nucleotide/cysteinyl leukotriene receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNJ8 Tbio ATP-sensitive inward rectifier potassium channel 8 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
P2RY6 Tchem P2Y purinoceptor 6 (9 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
P2RY14 Tchem P2Y purinoceptor 14 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYSLTR1 Tclin Cysteinyl leukotriene receptor 1 (2118 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
P2RY6 Tchem Pyrimidinergic receptor P2Y6 (717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
P2RY4 Tchem Pyrimidinergic receptor P2Y4 (598 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
P2RY1 Tchem Purinergic receptor P2Y1 (1327 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CAD Tchem Dihydroorotase (27 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
P2RY2 Tclin Purinergic receptor P2Y2 (1109 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
P2RY14 Tchem Purinergic receptor P2Y14 (692 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RNASE1 Tchem Ribonuclease pancreatic (45 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ENPP3 Tchem Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (241 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ENPP1 Tchem Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (635 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OGT Tchem UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (206 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GPR17 Tchem Uracil nucleotide/cysteinyl leukotriene receptor (291 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Iap Intestinal alkaline phosphatase (419 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
glf UDP-galactopyranose mutase (153 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
pfk 6-phospho-1-fructokinase (7870 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Serum (58 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SRN Seminal ribonuclease (5 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
P2ry14 P2Y purinoceptor 14 (107 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate
INCHI InChI=1S/C9H14N2O12P2/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChi Key XCCTYIAWTASOJW-XVFCMESISA-N
Canonical SMILES O[C@@H]1[C@@H](COP(=O)(OP(=O)(O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O
Isomeric SMILES C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O)O)O
PubChem CID 6031

Certificates

Certificate of Analysis(COA)

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Related Documents

Citations of This Product

1. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin.  (2023)  A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation.  ANALYTICAL SCIENCES,    (1-7).  [PMID:37843729] [10.1007/s44211-023-00430-5]
2. Tao Chen, Qi Wang, Qiqi Wang, Mencuo La, Yulin Li, Liangliang He, Denglang Zou.  (2022)  Ab initio calculation based solvent system selection in silico for counter-current chromatography: Separation of resibufogenin glycosylation products.  JOURNAL OF CHROMATOGRAPHY A,  1686  (463649).  [PMID:36423357] [10.1016/j.chroma.2022.463649]
3. Denglang Zou, Yunbin Cui, Si Li, Duocheng Sang, Weimeng Liu, Tianshu Zhao, Xueli Gu, Tao Chen, Yulin Li.  (2021)  The applicability of high-speed counter-current chromatography for preparative separation of biosynthesis products: Glycosylation products as example.  JOURNAL OF SEPARATION SCIENCE,  44  (24): (4368-4375).  [PMID:34687498] [10.1002/jssc.202100544]
4. Qiqi Wang, Tao Chen, Yunbin Cui, Si Li, Xinhao Jiang, Guodong Zhao, Yulin Li, Denglang Zou.  (2021)  The applicability of pH-zone-refining counter-current chromatography for preparative separation of biosynthesis products: Glycosylation products as example.  JOURNAL OF CHROMATOGRAPHY A,  1657  (462582).  [PMID:34614468] [10.1016/j.chroma.2021.462582]
5. Guimei Wang, Xiaoxue Jiang, Nanyan Fu.  (2019)  Near-infrared squaraine fluorescent probe for imaging adenosine 5′-triphosphate in live cells.  DYES AND PIGMENTS,  171  (107698).  [PMID:] [10.1016/j.dyepig.2019.107698]

References

1. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin.  (2023)  A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation.  ANALYTICAL SCIENCES,    (1-7).  [PMID:37843729] [10.1007/s44211-023-00430-5]
2. Tao Chen, Qi Wang, Qiqi Wang, Mencuo La, Yulin Li, Liangliang He, Denglang Zou.  (2022)  Ab initio calculation based solvent system selection in silico for counter-current chromatography: Separation of resibufogenin glycosylation products.  JOURNAL OF CHROMATOGRAPHY A,  1686  (463649).  [PMID:36423357] [10.1016/j.chroma.2022.463649]
3. Denglang Zou, Yunbin Cui, Si Li, Duocheng Sang, Weimeng Liu, Tianshu Zhao, Xueli Gu, Tao Chen, Yulin Li.  (2021)  The applicability of high-speed counter-current chromatography for preparative separation of biosynthesis products: Glycosylation products as example.  JOURNAL OF SEPARATION SCIENCE,  44  (24): (4368-4375).  [PMID:34687498] [10.1002/jssc.202100544]
4. Qiqi Wang, Tao Chen, Yunbin Cui, Si Li, Xinhao Jiang, Guodong Zhao, Yulin Li, Denglang Zou.  (2021)  The applicability of pH-zone-refining counter-current chromatography for preparative separation of biosynthesis products: Glycosylation products as example.  JOURNAL OF CHROMATOGRAPHY A,  1657  (462582).  [PMID:34614468] [10.1016/j.chroma.2021.462582]
5. Guimei Wang, Xiaoxue Jiang, Nanyan Fu.  (2019)  Near-infrared squaraine fluorescent probe for imaging adenosine 5′-triphosphate in live cells.  DYES AND PIGMENTS,  171  (107698).  [PMID:] [10.1016/j.dyepig.2019.107698]

Solution Calculators