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ulevostinag , CAS No.U614654, Agonist of stimulator of interferon response cGAMP interactor 1

ulevostinag , CAS No.U614654, Agonist of stimulator of interferon response cGAMP interactor 1

Item Number

U614654

Grouped product items
SKU	Size	Availability	Price	Qty
U614654-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$560.90
U614654-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,500.90

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Basic Description

Synonyms	compound 26;MK-1454;MK1454
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of stimulator of interferon response cGAMP interactor 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

INCHI	InChI=1S/C20H22F2N10O9P2S2/c21-8-6-1-36-42(34,44)40-12-7(39-18(9(12)22)31-4-27-10-14(23)25-3-26-15(10)31)2-37-43(35,45)41-13(8)19(38-6)32-5-28-11-16(32)29-20(24)30-17(11)33/h3-9,12-13,18-19H,1-2H2,(H,34,44)(H,35,45)(H2,23,25,26)(H3,24,29,30,33)/t6-,7-,8-,9+,12-,13-,18-,19-,42-,43-/m1/s1
InChi Key	YSUIQYOGTINQIN-CLMXYZJCSA-N
Canonical SMILES	Nc1ncnc2c1ncn2[C@H]1[C@@H](F)[C@@H]2O[P@](=O)(S)OC[C@@H]3[C@H]([C@@H](O[P@@](=O)(OC[C@H]2O1)S)[C@@H](O3)n1c2nc(N)[nH]c(=O)c2nc1)F
PubChem CID	149419198

PubChem CID	149419198

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1. Chang W, Altman MD, Lesburg CA, Perera SA, Piesvaux JA, Schroeder GK, Wyss DF, Cemerski S, Chen Y, DiNunzio E et al.. (2022) Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer.. J Med Chem, 65 (7): (5675-5689). [PMID:35332774]

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