Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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U288828-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $173.90 | |
U288828-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $89.90 | |
U288828-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $293.90 | |
U288828-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $279.90 | |
U288828-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $593.90 |
Potent G9a and GLP inhibitor
Synonyms | BDBM50300041 | XXB19648 | 7-[3-(Dimethylamino)propoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-4-quinazolinamine | AKOS024457835 | BS-14469 | C26H43N7O2 | 7-(3-(dimethylamino)propoxy)-6-methoxy-2-(4-methyl-1,4-diaz |
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Specifications & Purity | ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Potent G9a and GLP inhibitor (IC50values are 15 and 20 nM in a ThioGlo assay, respectively). Exhibits >1000-fold selectivity for G9a over SET7, SET8 and SET9. |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine |
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INCHI | InChI=1S/C26H43N7O2/c1-30(2)10-7-17-35-24-19-22-21(18-23(24)34-5)25(27-20-8-13-32(4)14-9-20)29-26(28-22)33-12-6-11-31(3)15-16-33/h18-20H,6-17H2,1-5H3,(H,27,28,29) |
InChi Key | XIVUGRBSBIXXJE-UHFFFAOYSA-N |
Canonical SMILES | CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)C)OC)OCCCN(C)C |
Isomeric SMILES | CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)C)OC)OCCCN(C)C |
PubChem CID | 44251522 |
Molecular Weight | 485.67 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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L2319414 | Certificate of Analysis | Nov 27, 2023 | U288828 |
L2319415 | Certificate of Analysis | Nov 27, 2023 | U288828 |
L2319416 | Certificate of Analysis | Nov 27, 2023 | U288828 |
L2319417 | Certificate of Analysis | Nov 27, 2023 | U288828 |
L2319418 | Certificate of Analysis | Nov 27, 2023 | U288828 |
L2319419 | Certificate of Analysis | Nov 27, 2023 | U288828 |
L2319420 | Certificate of Analysis | Nov 27, 2023 | U288828 |
L2319421 | Certificate of Analysis | Nov 27, 2023 | U288828 |
Solubility | Solvent:1eq. HCl, Max Conc. mg/mL: 48.57, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 48.57, Max Conc. mM: 100 |
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