UNC0379 is a selective, substrate competitive inhibitor of N-lysine methyltransferase SETD8 with IC50 of 7.9 μM, high selectivity over 15 other methyltransferases.
Storage Temp
Store at -80°C
Shipped In
Ice chest + Ice pads
Product Description
Information
UNC0379 UNC0379 is a selective, substrate competitive inhibitor of N-lysine methyltransferase SETD8 with IC50 of 7.9 μM, high selectivity over 15 other methyltransferases.
Targets
SETD8 (Cell-free assay) 7.3 μM
In vitro
UNC0379 is competitive with the peptide substrate and noncompetitive with the cofactor SAM.
Product Properties
ALogP
4.545
HBD Count
1
Rotatable Bond
10
Associated Targets(Human)
DNMT1Tclin DNA (cytosine-5)-methyltransferase 1 (978 Activities)
