UNC669 - 10mM in DMSO, high purity , CAS No.1314241-44-5

  • 10mM in DMSO
Item Number
U421217
Grouped product items
SKUSizeAvailabilityPrice Qty
U421217-1ml
1ml
Available within 8-12 weeks(?)
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$105.90

Selective, competitive L3MBTL antagonist

Basic Description

Synonyms1314241-44-5 | UNC669 | UNC 669 | (5-bromopyridin-3-yl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone | UNC-669 | (5-bromopyridin-3-yl)-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | CHEMBL1235119 | 3-Bromo-5-[(4-Pyrrolidin-1-Ylpiperidin-1-Yl)carbonyl]pyridine | C15H20BrN3O |
Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsSelective, competitive L3MBTL antagonist (IC 50 = 5 µM). Inhibits L3MBTL induced transcription repression. Active in vitro .
Storage TempStore at -80°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

AOX1 Tchem Aldehyde oxidase (429 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L3MBTL1 Tchem Lethal(3)malignant brain tumor-like protein 1 (14536 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L3MBTL3 Tchem Lethal(3)malignant brain tumor-like protein 3 (224 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L3MBTL4 Tbio Lethal(3)malignant brain tumor-like protein 4 (125 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MBTD1 Tbio MBT domain-containing protein 1 (145 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SFMBT1 Tbio Scm-like with four mbt domains 1, isoform CRA_b (107 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PHF13 Tbio PHD finger protein 13 (2 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX7 Tchem Chromobox protein homolog 7 (354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM5A Tchem Lysine-specific demethylase 5A (893 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PHF23 Tbio PHD finger protein 23 (81 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TP53BP1 Tbio Tumor suppressor p53-binding protein 1 (103 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UHRF1 Tbio E3 ubiquitin-protein ligase UHRF1 (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (5-bromopyridin-3-yl)-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone
INCHI InChI=1S/C15H20BrN3O/c16-13-9-12(10-17-11-13)15(20)19-7-3-14(4-8-19)18-5-1-2-6-18/h9-11,14H,1-8H2
InChi Key CQERVFFAOOUFEQ-UHFFFAOYSA-N
Canonical SMILES C1CCN(C1)C2CCN(CC2)C(=O)C3=CC(=CN=C3)Br
Isomeric SMILES C1CCN(C1)C2CCN(CC2)C(=O)C3=CC(=CN=C3)Br
PubChem CID 46931242
Molecular Weight 338.24

Certificates

Certificate of Analysis(COA)

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Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

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