Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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U425336-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $47.90 |
Allosteric regulator and coenzyme
Synonyms | uracil | 66-22-8 | 2,4-Dihydroxypyrimidine | 2,4(1H,3H)-Pyrimidinedione | Pyrod | pyrimidine-2,4(1H,3H)-dione | 2,4-Pyrimidinediol | 2,4-Dioxopyrimidine | pyrimidine-2,4-diol | Hybar X | 2,4-Pyrimidinedione | Pirod | 51953-14-1 | 1H-Pyrimidine-2,4-dione | RU 12709 | Uracil [USAN] | Uraz |
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Specifications & Purity | Moligand™, 10mM in DMSO |
Biochemical and Physiological Mechanisms | Allosteric regulator and coenzyme. Fundamental component of RNA. Forms base pairs with adenine. Shows antitumor effects in vivo. Orally active. |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
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IUPAC Name | 1H-pyrimidine-2,4-dione |
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INCHI | InChI=1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8) |
InChi Key | ISAKRJDGNUQOIC-UHFFFAOYSA-N |
Canonical SMILES | C1=CNC(=O)NC1=O |
Isomeric SMILES | C1=CNC(=O)NC1=O |
WGK Germany | 2 |
RTECS | YQ8650000 |
PubChem CID | 1174 |
Molecular Weight | 112.09 |
Beilstein | 507828 |
Enter Lot Number to search for COA:
Sensitivity | Moisture sensitive. |
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Melt Point(°C) | 335°C |
Pictogram(s) | GHS08, GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 2 |
RTECS | YQ8650000 |
Merck Index | 9850 |
1. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin. (2023) A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation. ANALYTICAL SCIENCES, (1-7). [PMID:37843729] |
2. Chao Liu, Rui Wang, Jie Li, Feiyue Cheng, Xian Shu, Huiwei Zhao, Qiong Xue, Haiying Yu, Aici Wu, Lingyun Wang, Sushu Hu, Yihan Zhang, Jun Yang, Hua Xiang, Ming Li. (2023) Widespread RNA-based cas regulation monitors crRNA abundance and anti-CRISPR proteins. Cell Host & Microbe, [PMID:37659410] |
3. Fei Wang, Fan Yang, Jiawei Liu, Quan Bai. (2023) Studies on the retention mechanism of solutes in hydrophilic interaction chromatography using stoichiometric displacement theory II. HILIC/RPLC dual-retention mechanism of solutes in hydrophilic interaction chromatography over the entire range of water concentration in mobile phase. TALANTA, 265 (124858). [PMID:37385194] |
4. Xubao Jiang, Suisui Wang, Xiang Zheng Kong. (2023) Quenching mechanism of PEG emission by pyrimidines and their detections using PEG as fluorescent sensor. CHEMICAL ENGINEERING JOURNAL, 468 (143617). [PMID:] |
5. Ye Shu, Tong Chen, Tao Liu, Hechen Xu, Jinjin He, Zhihui Cai, Wanning Zhu, Zihan Zhao, Jun Jiang. (2023) Preparation and characterization of mixed-mode hydrophilic stationary phase based on triple hydrophilic functionalized moieties and its application to traditional Chinese herbal compound. MICROCHEMICAL JOURNAL, 191 (108863). [PMID:] |
6. Ran Xin, Meng Dong, Yu-Ying Zhang, Xu-Hui Huang, Xiu-Ping Dong, Lei Qin. (2023) Development and validation of a HILIC-MS/MS method for simultaneous quantitative of taste-active compounds in foods. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 120 (105302). [PMID:] |
7. Yijing Liu, Lan Xu. (2023) Layer-by-Layer Assembly of Two-Dimensional Monolayer Films of Gold Nanoparticles for Electrochemical Determination of Melamine. ANALYTICAL LETTERS, [PMID:] |
8. Lvyuan Fan, Zhiyu Pan, Xu Liao, Yilin Zhong, Juan Guo, Rui Pang, Xinhai Chen, Guozhu Ye, Yubin Su. (2023) Uracil restores susceptibility of methicillin-resistant Staphylococcus aureus to aminoglycosides through metabolic reprogramming. Frontiers in Pharmacology, 14 (1133685). [PMID:36762116] |
9. Chaohong Gao, Yubing Wang, Heng Zhang, Wei Hang. (2023) Titania Nanosheet as a Matrix for Surface-Assisted Laser Desorption/Ionization Mass Spectrometry Analysis and Imaging. ANALYTICAL CHEMISTRY, 95 (2): (650–658). [PMID:36577518] |
10. Wen-Bo Xie, Hao Li, Lei Zeng, Li-Juan Jiang, Wen Li, Lu Xia, Fu-Hou Lei. (2023) Separation of Panax notoginseng saponins on modified rosin ester-bonded silica stationary phase and its mechanism. ANALYTICA CHIMICA ACTA, 1239 (340661). [PMID:36628701] |
11. Kaijie Xu, Kangping Cui, Minshu Cui, Xueyan Liu, Xing Chen. (2023) Carbonyl heterocycle modified mesoporous carbon nitride in photocatalytic peroxydisulfate activation for enhanced ciprofloxacin removal: Performance and mechanism. JOURNAL OF HAZARDOUS MATERIALS, 444 (130412). [PMID:36403448] |
12. Ciyang Zhang, Xingen Xie, Shasha Feng, Wu Lei, Mingzhu Xia, Fengyun Wang, Hualai Wang. (2023) Sensitive fluorescent detection and micromechanism of Mn-doped CuS probe for oxytetracycline hydrochloride. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 284 (121768). [PMID:36049299] |
13. Yanyan Wang, Liuqian Bao, Jiajing Sun, Yuanyuan Ding, Jiasheng Shi, Zhengyu Duan, Zhiyong Chen. (2022) Superhydrophobic fluorinated microspheres for fluorous affinity chromatography. JOURNAL OF CHROMATOGRAPHY A, 1680 (463428). [PMID:36001909] |
14. Hao-Fei Sun, Yuan-Yuan Cui, Chang-Qing Zhen, Cheng-Xiong Yang. (2023) Monomer-mediated fabrication of microporous organic network@silica microsphere for reversed-phase/hydrophilic interaction mixed-mode chromatography. TALANTA, 251 (123763). [PMID:35932636] |
15. Hanwen Liu, Ying Liu, Ting Zhou, Penghui Zhou, Jianguo Li, Anping Deng. (2022) Ultrasensitive and Specific Detection of Anticancer Drug 5-Fluorouracil in Blood Samples by a Surface-Enhanced Raman Scattering (SERS)-Based Lateral Flow Immunochromatographic Assay. MOLECULES, 27 (13): (4019). [PMID:35807264] |
16. Ting Zhou, Guangzhao He, Changjia Hu, Kang Wu, Ying Liu, Jianguo Li, Anping Deng. (2022) Development of a highly sensitive and specific monoclonal antibody-based ELISA coupled with immuno-affinity extraction for the detection of anticancer drug 5-fluorouracil in blood samples. TALANTA, 249 (123655). [PMID:35696979] |
17. Qiqin Wang, Lingjue Sun, Huihui Wu, Ning Deng, Xianglong Zhao, Jingwei Zhou, Tingting Zhang, Hai Han, Zhengjin Jiang. (2022) Rapid fabrication of zwitterionic sulfobetaine vinylimidazole-based monoliths via photoinitiated copolymerization for hydrophilic interaction chromatography. Journal of Pharmaceutical Analysis, 12 (783). [PMID:36320596] |
18. Yan Wu, Kaixing Luo, Yanjuan Liu, Wei Chen, Zhengwu Bai, Sheng Tang. (2022) Innovative preparation of ureido/dodecyl dual-functionalized silica as a versatile mixed-mode stationary phase for high-resolution chromatographic separations. JOURNAL OF CHROMATOGRAPHY A, 1665 (462834). [PMID:35085896] |
19. Kaixuan Li, Ding Li, Yan Zhang. (2021) Terahertz Spectral Properties of 5-Substituted Uracils. SENSORS, 21 (24): (8292). [PMID:34960387] |
20. Xican Li. (2013-07-23) Solvent effects and improvements in the deoxyribose degradation assay for hydroxyl radical-scavenging.. Food chemistry, 141 ((3)): (2083-2088). [PMID:23870931] |
21. Yun Li,Jiajia Yang,Jing Jin,Xiaoli Sun,Longxing Wang,Jiping Chen. (2014-03-19) New reversed-phase/anion-exchange/hydrophilic interaction mixed-mode stationary phase based on dendritic polymer-modified porous silica.. Journal of chromatography. A, 1337 (133-139). [PMID:24630062] |
22. Dan-Qian Chen,Gang Cao,Hua Chen,Dan Liu,Wei Su,Xiao-Yong Yu,Nosratola D Vaziri,Xiu-Hua Liu,Xu Bai,Li Zhang,Ying-Yong Zhao. (2017-03-28) Gene and protein expressions and metabolomics exhibit activated redox signaling and wnt/β-catenin pathway are associated with metabolite dysfunction in patients with chronic kidney disease.. Redox biology, 12 (505-521). [PMID:28343144] |
1. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin. (2023) A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation. ANALYTICAL SCIENCES, (1-7). [PMID:37843729] |
2. Chao Liu, Rui Wang, Jie Li, Feiyue Cheng, Xian Shu, Huiwei Zhao, Qiong Xue, Haiying Yu, Aici Wu, Lingyun Wang, Sushu Hu, Yihan Zhang, Jun Yang, Hua Xiang, Ming Li. (2023) Widespread RNA-based cas regulation monitors crRNA abundance and anti-CRISPR proteins. Cell Host & Microbe, [PMID:37659410] |
3. Fei Wang, Fan Yang, Jiawei Liu, Quan Bai. (2023) Studies on the retention mechanism of solutes in hydrophilic interaction chromatography using stoichiometric displacement theory II. HILIC/RPLC dual-retention mechanism of solutes in hydrophilic interaction chromatography over the entire range of water concentration in mobile phase. TALANTA, 265 (124858). [PMID:37385194] |
4. Xubao Jiang, Suisui Wang, Xiang Zheng Kong. (2023) Quenching mechanism of PEG emission by pyrimidines and their detections using PEG as fluorescent sensor. CHEMICAL ENGINEERING JOURNAL, 468 (143617). [PMID:] |
5. Ye Shu, Tong Chen, Tao Liu, Hechen Xu, Jinjin He, Zhihui Cai, Wanning Zhu, Zihan Zhao, Jun Jiang. (2023) Preparation and characterization of mixed-mode hydrophilic stationary phase based on triple hydrophilic functionalized moieties and its application to traditional Chinese herbal compound. MICROCHEMICAL JOURNAL, 191 (108863). [PMID:] |
6. Ran Xin, Meng Dong, Yu-Ying Zhang, Xu-Hui Huang, Xiu-Ping Dong, Lei Qin. (2023) Development and validation of a HILIC-MS/MS method for simultaneous quantitative of taste-active compounds in foods. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 120 (105302). [PMID:] |
7. Yijing Liu, Lan Xu. (2023) Layer-by-Layer Assembly of Two-Dimensional Monolayer Films of Gold Nanoparticles for Electrochemical Determination of Melamine. ANALYTICAL LETTERS, [PMID:] |
8. Lvyuan Fan, Zhiyu Pan, Xu Liao, Yilin Zhong, Juan Guo, Rui Pang, Xinhai Chen, Guozhu Ye, Yubin Su. (2023) Uracil restores susceptibility of methicillin-resistant Staphylococcus aureus to aminoglycosides through metabolic reprogramming. Frontiers in Pharmacology, 14 (1133685). [PMID:36762116] |
9. Chaohong Gao, Yubing Wang, Heng Zhang, Wei Hang. (2023) Titania Nanosheet as a Matrix for Surface-Assisted Laser Desorption/Ionization Mass Spectrometry Analysis and Imaging. ANALYTICAL CHEMISTRY, 95 (2): (650–658). [PMID:36577518] |
10. Wen-Bo Xie, Hao Li, Lei Zeng, Li-Juan Jiang, Wen Li, Lu Xia, Fu-Hou Lei. (2023) Separation of Panax notoginseng saponins on modified rosin ester-bonded silica stationary phase and its mechanism. ANALYTICA CHIMICA ACTA, 1239 (340661). [PMID:36628701] |
11. Kaijie Xu, Kangping Cui, Minshu Cui, Xueyan Liu, Xing Chen. (2023) Carbonyl heterocycle modified mesoporous carbon nitride in photocatalytic peroxydisulfate activation for enhanced ciprofloxacin removal: Performance and mechanism. JOURNAL OF HAZARDOUS MATERIALS, 444 (130412). [PMID:36403448] |
12. Ciyang Zhang, Xingen Xie, Shasha Feng, Wu Lei, Mingzhu Xia, Fengyun Wang, Hualai Wang. (2023) Sensitive fluorescent detection and micromechanism of Mn-doped CuS probe for oxytetracycline hydrochloride. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 284 (121768). [PMID:36049299] |
13. Yanyan Wang, Liuqian Bao, Jiajing Sun, Yuanyuan Ding, Jiasheng Shi, Zhengyu Duan, Zhiyong Chen. (2022) Superhydrophobic fluorinated microspheres for fluorous affinity chromatography. JOURNAL OF CHROMATOGRAPHY A, 1680 (463428). [PMID:36001909] |
14. Hao-Fei Sun, Yuan-Yuan Cui, Chang-Qing Zhen, Cheng-Xiong Yang. (2023) Monomer-mediated fabrication of microporous organic network@silica microsphere for reversed-phase/hydrophilic interaction mixed-mode chromatography. TALANTA, 251 (123763). [PMID:35932636] |
15. Hanwen Liu, Ying Liu, Ting Zhou, Penghui Zhou, Jianguo Li, Anping Deng. (2022) Ultrasensitive and Specific Detection of Anticancer Drug 5-Fluorouracil in Blood Samples by a Surface-Enhanced Raman Scattering (SERS)-Based Lateral Flow Immunochromatographic Assay. MOLECULES, 27 (13): (4019). [PMID:35807264] |
16. Ting Zhou, Guangzhao He, Changjia Hu, Kang Wu, Ying Liu, Jianguo Li, Anping Deng. (2022) Development of a highly sensitive and specific monoclonal antibody-based ELISA coupled with immuno-affinity extraction for the detection of anticancer drug 5-fluorouracil in blood samples. TALANTA, 249 (123655). [PMID:35696979] |
17. Qiqin Wang, Lingjue Sun, Huihui Wu, Ning Deng, Xianglong Zhao, Jingwei Zhou, Tingting Zhang, Hai Han, Zhengjin Jiang. (2022) Rapid fabrication of zwitterionic sulfobetaine vinylimidazole-based monoliths via photoinitiated copolymerization for hydrophilic interaction chromatography. Journal of Pharmaceutical Analysis, 12 (783). [PMID:36320596] |
18. Yan Wu, Kaixing Luo, Yanjuan Liu, Wei Chen, Zhengwu Bai, Sheng Tang. (2022) Innovative preparation of ureido/dodecyl dual-functionalized silica as a versatile mixed-mode stationary phase for high-resolution chromatographic separations. JOURNAL OF CHROMATOGRAPHY A, 1665 (462834). [PMID:35085896] |
19. Kaixuan Li, Ding Li, Yan Zhang. (2021) Terahertz Spectral Properties of 5-Substituted Uracils. SENSORS, 21 (24): (8292). [PMID:34960387] |
20. Xican Li. (2013-07-23) Solvent effects and improvements in the deoxyribose degradation assay for hydroxyl radical-scavenging.. Food chemistry, 141 ((3)): (2083-2088). [PMID:23870931] |
21. Yun Li,Jiajia Yang,Jing Jin,Xiaoli Sun,Longxing Wang,Jiping Chen. (2014-03-19) New reversed-phase/anion-exchange/hydrophilic interaction mixed-mode stationary phase based on dendritic polymer-modified porous silica.. Journal of chromatography. A, 1337 (133-139). [PMID:24630062] |
22. Dan-Qian Chen,Gang Cao,Hua Chen,Dan Liu,Wei Su,Xiao-Yong Yu,Nosratola D Vaziri,Xiu-Hua Liu,Xu Bai,Li Zhang,Ying-Yong Zhao. (2017-03-28) Gene and protein expressions and metabolomics exhibit activated redox signaling and wnt/β-catenin pathway are associated with metabolite dysfunction in patients with chronic kidney disease.. Redox biology, 12 (505-521). [PMID:28343144] |