Uridine 5′-monophosphate - 98%, high purity , CAS No.58-97-9

Item Number
U171107
Grouped product items
SKUSizeAvailabilityPrice Qty
U171107-1g
1g
In stock
$51.90
U171107-5g
5g
In stock
$171.90
U171107-25g
25g
In stock
$614.90
U171107-100g
100g
In stock
$1,716.90

Basic Description

Synonyms{[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid | AKOS016009839 | Uridine 5'-phosphorate | 2,4(1H,3H)-pyrimidinedione, 1-(5-O-phosphono-beta-D-ribofuranosyl)- | W-105350 | W-203212 | bmse0002
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsUridine 5'-monophosphate is a nucleotide monomer in RNA. It contains the nucleobase uracil, ribose and phosphate groups. UMP dietary supplement promotes neurotransmitter release and neurite outgrowth and also promotes membrane phospholipid production in a
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Product Description

Uridine 5′-monophosphate acts as a precursor for all pyrimidine nucleotides.

Associated Targets(Human)

CRBN Tclin Protein cereblon (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RGS4 Tchem Regulator of G-protein signaling 4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AGO2 Tbio Protein argonaute-2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
UMPS Tclin Uridine 5'-monophosphate synthase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CMPK1 Tchem UMP-CMP kinase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
P2RY6 Tchem P2Y purinoceptor 6 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
P2RY6 Tchem Pyrimidinergic receptor P2Y6 (717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UMPS Tclin Uridine 5'-monophosphate synthase (20 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CMPK1 Tchem UMP-CMP kinase (152 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CRBN Tclin Protein cereblon (139 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

ompdc Orotidine phosphate decarboxylase (9 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
pyrF Orotidine 5'-phosphate decarboxylase (39 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488179989
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488179989
IUPAC Name [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
INCHI InChI=1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChi Key DJJCXFVJDGTHFX-XVFCMESISA-N
Canonical SMILES C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)O)O)O
Isomeric SMILES C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O
PubChem CID 6030
Molecular Weight 324.18

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

13 results found

Lot NumberCertificate TypeDateItem
A2218134Certificate of AnalysisNov 04, 2024 U171107
E23231082Certificate of AnalysisFeb 15, 2023 U171107
E23231086Certificate of AnalysisFeb 15, 2023 U171107
E23231090Certificate of AnalysisFeb 15, 2023 U171107
E23231091Certificate of AnalysisFeb 15, 2023 U171107
E23231094Certificate of AnalysisFeb 15, 2023 U171107
E23231202Certificate of AnalysisFeb 15, 2023 U171107
E23231204Certificate of AnalysisFeb 15, 2023 U171107
E23231223Certificate of AnalysisFeb 15, 2023 U171107
K2422021Certificate of AnalysisFeb 15, 2023 U171107
A2218133Certificate of AnalysisDec 24, 2021 U171107
A2218148Certificate of AnalysisDec 24, 2021 U171107
A2219119Certificate of AnalysisDec 24, 2021 U171107

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Chemical and Physical Properties

SolubilityH2O: soluble 50 mg/mL, clear, colorless

Related Documents

Citations of This Product

1. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin.  (2023)  A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation.  ANALYTICAL SCIENCES,    (1-7).  [PMID:37843729] [10.1007/s44211-023-00430-5]
2. Xu Shichao, Wu Haifeng, Liu Siyuan, Du Peidong, Wang Hui, Yang Haijun, Xu Wenjie, Chen Shuangming, Song Li, Li Jikun, Shi Xinghua, Wang Zhen-Gang.  (2023)  A supramolecular metalloenzyme possessing robust oxidase-mimetic catalytic function.  Nature Communications,  14  (1): (1-14).  [PMID:37419896] [10.1038/s41467-023-39779-6]
3. Peidong Du, Yanzhe Shen, Baoli Zhang, Shan Li, Minzheng Gao, Ting Wang, Xiaokang Ding, Bingran Yu, Zhen-Gang Wang, Fu-Jian Xu.  (2023)  A H2O2-Supplied Supramolecular Material for Post-irradiated Infected Wound Treatment.  Advanced Science,  10  (9): (2206851).  [PMID:36709479] [10.1002/advs.202206851]
4. Yuqin Wang, Pingping Fan, Shanyu Zhang, Liying Wang, Xinyue Li, Wendong Jia, Yao Liu, Kefan Wang, Xiaoyu Du, Panke Zhang, Shuo Huang.  (2022)  Discrimination of Ribonucleoside Mono-, Di-, and Triphosphates Using an Engineered Nanopore.  ACS Nano,  16  (12): (21356–21365).  [PMID:36475606] [10.1021/acsnano.2c09662]
5. Cheng Jingliang, Fu Jiewen, Tan Qi, Liu Zhiying, Guo Kan, Zhang Lianmei, He Jiayue, Zhou Baixu, Liu Xiaoyan, Li Dabing, Fu Junjiang.  (2022)  The regulation of ISG20 expression on SARS-CoV-2 infection in cancer patients and healthy individuals.  Frontiers in Immunology,  13    [PMID:36177004] [10.3389/fimmu.2022.958898]
6. Yafei Hou, Xiaodan Pei, Yuancheng Wang, Luyuan Zhang, Xiaohui Wei, Hongyan Mao, Wuduo Zhao, Shusheng Zhang, Wenfen Zhang.  (2022)  Selective Detection of Nucleotides in Infant Formula Using an N-Rich Covalent Triazine Porous Polymer.  Nanomaterials,  12  (13): (2213).  [PMID:35808047] [10.3390/nano12132213]
7. Chen Pengfei, Wu Jing, Zhou Lei, Pu Qiaosheng.  (2021)  In situ controllable synthesis of Schiff base networks porous polymer coatings for open-tubular capillary electrochromatography.  MICROCHIMICA ACTA,  188  (3): (1-9).  [PMID:33586055] [10.1007/s00604-021-04740-1]
8. Guimei Wang, Xiaoxue Jiang, Nanyan Fu.  (2019)  Near-infrared squaraine fluorescent probe for imaging adenosine 5′-triphosphate in live cells.  DYES AND PIGMENTS,  171  (107698).  [PMID:] [10.1016/j.dyepig.2019.107698]
9. Qiqin Wang, Huihui Wu, Kun Peng, Hanying Jin, Huikai Shao, Yuqiang Wang, Jacques Crommen, Zhengjin Jiang.  (2018)  Hydrophilic polymeric monoliths containing choline phosphate for separation science applications.  ANALYTICA CHIMICA ACTA,  999  (184).  [PMID:29254571] [10.1016/j.aca.2017.11.032]
10. Chen Zhao, Yan Yang, Linfang Wei, Qinghua Guo, Hao Fang, Shaolin Chen, Qiang Hua.  (2017)  Simultaneous determination of intracellular nucleotides and coenzymes in Yarrowia lipolytica producing lipid and lycopene by capillary zone electrophoresis.  JOURNAL OF CHROMATOGRAPHY A,  1514  (120).  [PMID:28760603] [10.1016/j.chroma.2017.07.074]
11. Chusheng Liu, Haibin Li, Qiqin Wang, Jacques Crommen, Haibo Zhou, Zhengjin Jiang.  (2017)  Preparation and evaluation of 400 μm I.D. polymer-based hydrophilic interaction chromatography monolithic columns with high column efficiency.  JOURNAL OF CHROMATOGRAPHY A,  1509  (83).  [PMID:28629939] [10.1016/j.chroma.2017.06.034]

References

1. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin.  (2023)  A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation.  ANALYTICAL SCIENCES,    (1-7).  [PMID:37843729] [10.1007/s44211-023-00430-5]
2. Xu Shichao, Wu Haifeng, Liu Siyuan, Du Peidong, Wang Hui, Yang Haijun, Xu Wenjie, Chen Shuangming, Song Li, Li Jikun, Shi Xinghua, Wang Zhen-Gang.  (2023)  A supramolecular metalloenzyme possessing robust oxidase-mimetic catalytic function.  Nature Communications,  14  (1): (1-14).  [PMID:37419896] [10.1038/s41467-023-39779-6]
3. Peidong Du, Yanzhe Shen, Baoli Zhang, Shan Li, Minzheng Gao, Ting Wang, Xiaokang Ding, Bingran Yu, Zhen-Gang Wang, Fu-Jian Xu.  (2023)  A H2O2-Supplied Supramolecular Material for Post-irradiated Infected Wound Treatment.  Advanced Science,  10  (9): (2206851).  [PMID:36709479] [10.1002/advs.202206851]
4. Yuqin Wang, Pingping Fan, Shanyu Zhang, Liying Wang, Xinyue Li, Wendong Jia, Yao Liu, Kefan Wang, Xiaoyu Du, Panke Zhang, Shuo Huang.  (2022)  Discrimination of Ribonucleoside Mono-, Di-, and Triphosphates Using an Engineered Nanopore.  ACS Nano,  16  (12): (21356–21365).  [PMID:36475606] [10.1021/acsnano.2c09662]
5. Cheng Jingliang, Fu Jiewen, Tan Qi, Liu Zhiying, Guo Kan, Zhang Lianmei, He Jiayue, Zhou Baixu, Liu Xiaoyan, Li Dabing, Fu Junjiang.  (2022)  The regulation of ISG20 expression on SARS-CoV-2 infection in cancer patients and healthy individuals.  Frontiers in Immunology,  13    [PMID:36177004] [10.3389/fimmu.2022.958898]
6. Yafei Hou, Xiaodan Pei, Yuancheng Wang, Luyuan Zhang, Xiaohui Wei, Hongyan Mao, Wuduo Zhao, Shusheng Zhang, Wenfen Zhang.  (2022)  Selective Detection of Nucleotides in Infant Formula Using an N-Rich Covalent Triazine Porous Polymer.  Nanomaterials,  12  (13): (2213).  [PMID:35808047] [10.3390/nano12132213]
7. Chen Pengfei, Wu Jing, Zhou Lei, Pu Qiaosheng.  (2021)  In situ controllable synthesis of Schiff base networks porous polymer coatings for open-tubular capillary electrochromatography.  MICROCHIMICA ACTA,  188  (3): (1-9).  [PMID:33586055] [10.1007/s00604-021-04740-1]
8. Guimei Wang, Xiaoxue Jiang, Nanyan Fu.  (2019)  Near-infrared squaraine fluorescent probe for imaging adenosine 5′-triphosphate in live cells.  DYES AND PIGMENTS,  171  (107698).  [PMID:] [10.1016/j.dyepig.2019.107698]
9. Qiqin Wang, Huihui Wu, Kun Peng, Hanying Jin, Huikai Shao, Yuqiang Wang, Jacques Crommen, Zhengjin Jiang.  (2018)  Hydrophilic polymeric monoliths containing choline phosphate for separation science applications.  ANALYTICA CHIMICA ACTA,  999  (184).  [PMID:29254571] [10.1016/j.aca.2017.11.032]
10. Chen Zhao, Yan Yang, Linfang Wei, Qinghua Guo, Hao Fang, Shaolin Chen, Qiang Hua.  (2017)  Simultaneous determination of intracellular nucleotides and coenzymes in Yarrowia lipolytica producing lipid and lycopene by capillary zone electrophoresis.  JOURNAL OF CHROMATOGRAPHY A,  1514  (120).  [PMID:28760603] [10.1016/j.chroma.2017.07.074]
11. Chusheng Liu, Haibin Li, Qiqin Wang, Jacques Crommen, Haibo Zhou, Zhengjin Jiang.  (2017)  Preparation and evaluation of 400 μm I.D. polymer-based hydrophilic interaction chromatography monolithic columns with high column efficiency.  JOURNAL OF CHROMATOGRAPHY A,  1509  (83).  [PMID:28629939] [10.1016/j.chroma.2017.06.034]

Solution Calculators